• Resources
    • Learning Center
    • Blog
Add a Listing Advertise
  • Property Lists
  • Listings
    • Commercial Real Estate
  • Comparables
  • Owners
  • Maps
  1. Office Space
  2. PA
  3. Harrisburg
  • Details
  • Spaces Available
  • Contacts
  • Location
  • POI
For Lease

450 Powers Ave

450 Powers Ave, Harrisburg, PA 17109

25,599

SF Available
Just off I-83, along heavily traveled Union Deposit RoadMultiple suites coming available at 450 Powers Ave, a well-located professional/medical building just off I-83, along heavily traveled Union Deposit Road. Suites feature flexible layouts—including traditional medical suites, open-concept therapy space, and smaller medical/office configurations. The building also features a rare amenity: a full-sized indoor pool that could be utilized by a tenant, creating unique opportunities for wellness, rehabilitation, training, or specialty use.

Key features

  • Easy access to I-83, I-81, and PA Turnpike.
  • Excellent opportunity for quasi-medical uses, including urgent care center with unbelievable visibility to 30,000 VPD + signage potential.
  • Flexible zoning allows for various uses.
  • High population density in immediate submarket.
  • Located within 1/4 mile of new $100 million Pinnacle Health System's Regional Community General hospital campus.

Rental Details

  • Number of spaces 4
  • Total square feet available 25,599 SF
  • For Lease Contact for pricing
  • Space Types Medical Office, Creative Office
  • Lease Type NNN
  • Date Updated Mar 26, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 4 Spaces Available

Area 1 (Main Level)

  • Space Type Medical Office
  • Lease Rate $9.95/SF/YR
  • Total Space Available 10,425 SF
  • Photos
  • Floor Upper level
  • Divisible Space 10,425 - 25,935 SF
  • Available Date Immediate
  • Lease Type NNN
  • Renewal Option Yes
  • Sublease No
broker
William Gladstone

NAI Global

Area 2 (Lower Level)

  • Space Type Medical Office
  • Lease Rate $9.95/SF/YR
  • Total Space Available 6,067 SF
  • Photos
  • Floor Lower level (with separate exterior entrance)
  • Divisible Space 6,067 - 25,935 SF
  • Available Date Immediate
  • Lease Type NNN
  • Renewal Option Yes
  • Sublease No
broker
William Gladstone

NAI Global

Area 3 (Lower Level)

  • Space Type Medical Office
  • Lease Rate $9.95/SF/YR
  • Total Space Available 8,307 SF
  • Photos
  • Floor Lower level
  • Divisible Space 8,307 - 25,935 SF
  • Available Date Immediate
  • Lease Type NNN
  • Renewal Option Yes
  • Sublease No
broker
William Gladstone

NAI Global

Area 4 (Main Level)

  • Space Type Creative Office
  • Lease Rate Contact for pricing
  • Total Space Available 800 SF
  • Photos
  • Divisible Space 800 - 800 SF
  • Available Date Immediate
  • Lease Type NNN
  • Renewal Option Yes
  • Sublease No

This suite is one room (20' x 40'), on the gym side of the building. Could be a good use for a chiropractor, beauty salon, or another complimentary use.

broker
William Gladstone

NAI Global

Contacts

broker
William Gladstone

NAI Global

Building Details

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Property Size 64,169 SF
  • Lot Size 3.8 Acre
  • Parking Spaces Avail. 225
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1984
  • Date Updated Mar 26, 2026

Attachments

  • Property Brochure 1 ()opens in new window

Getting Around

  • Walk Score ®

    Somewhat Walkable (59)
  • Bike Score ®

    Somewhat Bikeable (45)
Powered by Walk Score ®

Location

  • City Harrisburg, PA
  • Zip Code 17109
  • Market Harrisburg
  • Map
  • Street

Points of Interest

Middletown

7.26 miles

M&H Railroad

7.83 miles

Gulf

0.32 miles

United

0.49 miles

Giant

0.66 miles

Sunoco

0.75 miles

Giant Food Gas

0.90 miles

Mobil Station

0.96 miles

Turkey Hill

1.60 miles

Liberty Gas Station

2.01 miles

Kwick Gas

2.04 miles

Shoppes at Susquehanna

2.05 miles

Sheetz Parking Lot

2.50 miles

Elmerton Avenue Lot

2.60 miles

UPMC Southgate Professional Building Parking Lot (Visitors & Staff Only)

2.87 miles

7th Street Garage

2.87 miles

5th St. Garage

2.91 miles

Shiny Shell Car Wash

1.94 miles

Sheetz

2.47 miles

Enterprise

3.77 miles

Cloud10 Carwashs

4.50 miles

Kwik Shine

6.91 miles

Team Blue

9.28 miles

Joe K's Brewhouse

0.10 miles

Chipotle

0.11 miles

Wendy's

0.16 miles

P.J. Whelihan's Pub + Restaurant

0.16 miles

Price Rite

0.17 miles

Chuck E. Cheese

0.18 miles

Jimmy John's

0.18 miles

Waffle House

0.19 miles

Subway

0.20 miles

Big Lots

0.23 miles

Giant

0.55 miles

Harrisburg Mall

1.70 miles

Colonial Park Mall

1.82 miles

Laliguras International Grocery

2.06 miles

ALDI

2.09 miles

Target

2.36 miles

JCPenney

2.42 miles

High Pointe Commons

2.48 miles

Community General Osteopathic Hospital

0.73 miles

Progress Fire Company Station 32

0.86 miles

Penbrook Police Department

0.99 miles

Paxtang Fire Company, Station 40

1.28 miles

CVS Pharmacy

1.82 miles

Lower Paxton Twp. Police

1.86 miles

Aspire Urgent Care

2.00 miles

Station 2

2.21 miles

Allison Hill Substation

2.25 miles

450 Powers Ave Listing Summary

  • Office Space Available at 450 Powers Ave

    Office space currently available at 450 Powers Ave adds up to a total of 25,599 square feet across 4 listing(s). The largest individual space listed offers 10,425 square feet. Property use types available for lease at this property include: medical office and creative office.

  • Learn More about 450 Powers Ave

    450 Powers Ave is located in the Harrisburg market and pertains to the 17109 zip code. The property incorporates a total of 25,599 square feet of space. 450 Powers Ave was built in 1984.

    Interested in researching more about this property? Access in-depth research on 450 Powers Ave, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

Contact Listing Broker
broker
William Gladstone

NAI Global

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Nearby Listings

939 E Park Dr

939 E Park Dr

939 E Park Dr, Harrisburg, PA
$18.50/SF/YR
Property
  • Office
  • 16,328 SF
Availability
  • 1 Space
  • 3,430 SF
750 East Park Drive

750 East Park Drive

750 East Park Drive, Harrisburg, PA
$17.95/SF/YR
Property
  • Office
  • 39,831 SF
Availability
  • 6 Spaces
  • 41,724 SF
651 East Park Drive

651 East Park Drive

651 East Park Drive, Harrisburg, PA
$18.50/SF/YR
Property
  • Office
  • 46,241 SF
Availability
  • 4 Spaces
  • 34,362 SF
Progress Plaza

Progress Plaza

99 North Progress Avenue, Harrisburg, PA
Contact for pricing
Property
  • Retail
  • 53,600 SF
Availability
  • 4 Spaces
  • 2,720 SF
4700 Union Deposit Rd, 4 Suites

4700 Union Deposit Rd, 4 Suites

4700 Union Deposit Rd, 4 Suites, Harrisburg, PA
$5.95 - $7.95/SF/YR
Property
  • Office
  • 30,000 SF
Availability
  • 4 Spaces
  • 17,217 SF

Popular Searches

  • Philadelphia Office Space for Rent
  • Rockville Office Space for Rent
  • Lancaster Office Space for Rent
  • Harrisburg Office Space for Rent
  • Annapolis Office Space for Rent
  • Mechanicsburg Office Space for Rent
  • Camp Hill Office Space for Rent
  • Lemoyne Office Space for Rent
  • Lebanon Office Space for Rent
  • Hershey Office Space for Rent
  • Philadelphia Commercial Real Estate
  • Harrisburg Commercial Real Estate
  • Lancaster Commercial Real Estate
  • Annapolis Commercial Real Estate
  • Gettysburg Commercial Real Estate
  • Rockville Commercial Real Estate
  • Camp Hill Commercial Real Estate
  • Lebanon Commercial Real Estate
  • Mechanicsburg Commercial Real Estate
  • Dillsburg Commercial Real Estate
Copyright 2003-2026, PropertyShark.com
Contact Us  |  About  |  Privacy Policy  |  Terms Of Service  |  Sitemaps