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East Cambridge, Cambridge, MA Office Spaces for Rent - 38 Spaces

  • American Twine Office Park - Cambridge
    222 3rd Street, East Cambridge, Cambridge, MA
    For Lease
    • $93/Sqft/Year
    Property
    • Office
    • 114,364 Sqft
    Availability
    • 8 Spaces
    • 28,280 Sqft
    Year Built
    • 1918
    View Details
  • Alexandria Center at Kendall Square - 50 Binney Street - Cambridge
    50 Binney Street, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 278,448 Sqft
    Availability
    • 1 Space
    • 267,278 Sqft
    Year Built
    • 2017
    View Details
  • One Charles Park - Cambridge
    1 Charles Park, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 109,989 Sqft
    Availability
    • 1 Space
    • 9,593 Sqft
    Year Built
    • 1994
    View Details
  • One Broadway - Cambridge
    1 Broadway, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 312,704 Sqft
    Availability
    • 3 Spaces
    • 37,657 Sqft
    Year Built
    • 1969
    View Details
  • 55 Cambridge Pkwy - Cambridge
    55 Cambridge Pkwy, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 275,968 Sqft
    Availability
    • 1 Space
    • 21,389 Sqft
    Year Built
    • 1985
    View Details
  • 245 First Street - Cambridge
    245 First Street, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 164,704 Sqft
    Availability
    • 3 Spaces
    • 40,419 Sqft
    Year Built
    • 1985
    View Details
  • Alexandria Center at Kendall Square - Cambridge
    100 Binney Street, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 417,000 Sqft
    Availability
    • 4 Spaces
    • 166,000 Sqft
    Year Built
    • 2018
    View Details
  • 263-277 Cambridge St - Cambridge
    263-277 Cambridge St, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 21,552 Sqft
    Availability
    • 4 Spaces
    • 16,771 Sqft
    Year Built
    • 1965
    View Details
  • 15-17 Winter Street - Cambridge
    15-17 Winter Street, East Cambridge, Cambridge, MA
    For Lease
    • $29/Sqft/Year
    Property
    • Office
    • 3,234 Sqft
    Availability
    • 2 Spaces
    • 3,234 Sqft
    View Details
  • Two Canal Park - Cambridge
    Two Canal Park, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 199,000 Sqft
    Availability
    • 1 Space
    • 41,200 Sqft
    Year Built
    • 1999
    View Details
  • 15-17 Winter Street - Cambridge
    15-17 Winter Street, East Cambridge, Cambridge, MA
    For Sale
    • Contact for pricing
    Property
    • Office
    • 3,234 Sqft
    Availability Contact for availability
    Year Built
    • 1944
    View Details
  • CambridgeSide - 100 Cambridgeside Place Office - Cambridge
    100 Cambridgeside Place, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 162,000 Sqft
    Availability
    • 1 Space
    • 162,000 Sqft
    Year Built
    • 2021
    View Details
  • 303 Third Street - Cambridge
    303 Third Street, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 2,834 Sqft
    View Details
  • 1 Charles Park - Cambridge
    1 Charles Park, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 109,427 Sqft
    Availability
    • 1 Space
    • 15,975 Sqft
    Year Built
    • 1989
    View Details
  • 189 Cambridge Street - Cambridge
    189 Cambridge Street, East Cambridge, Cambridge, MA
    For Lease
    • $40 - $42/Sqft/Year
    Property
    • Office
    • 10,295 Sqft
    Availability
    • 1 Space
    • 912 Sqft
    View Details
  • Cambridge Crossing - JK Site - Cambridge
    222 Jacobs Street, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 460,000 Sqft
    Availability
    • 1 Space
    • 25,263 Sqft
    Year Built
    • 2020
    View Details

Office Space Listings Overview

There’s a total of 19 office listings available for rent in East Cambridge, Cambridge, MA. Across 38 unique spaces, there is a grand total of 965,446 square feet. The variety of spaces range from 912 square feet to 267,278 square feet. You can also filter your search by location, price, available space, asking price and more, making it easy to select what works best for you or your business.

East Cambridge, Cambridge, MA Commercial Inventory Breakdown

Office Spaces

Total: 13,287,507 SF

Data provided by Yardi Matrix, properties over 50k SF, includes office with retail

By square footage range:

  • 50k to 100k SF: 288,595 SF / 2.17% of total office
  • 100k to 500k SF: 10,847,912 SF / 81.64% of total office
  • 500k to 1M SF: 2,151,000 SF / 16.19% of total office

By class:

  • Class A: 9,361,373 SF / 70.45% of total office
  • Class B: 1,153,346 SF / 8.68% of total office
  • Class C: 99,513 SF / 0.75% of total office

Top 10 Largest Office Buildings

in East Cambridge

Office building Address Sqft Year built
Cambridge Crossing - Parcel G 350 Water Street, 02141 501,000 2021
Cambridge Crossing - JK Site 222 Jacobs Street, 02141 460,000 2020
Akamai Global Headquarters 145 Broadway, 02142 453,768 2019
Alexandria Center at Kendall Square 100 Binney Street, 02142 417,000 2018
Cambridge Crossing - Parcel H 450 Water Street, 02141 405,000 2021
Alexandria Center at Kendall Square - 215 First Street 215 1st Street, 02142 366,723 2010
The Genzyme Center 500 Kendall Street, 02142 349,325 2002
One Broadway 1 Broadway, 02142 312,704 1969
Alexandria Center at Kendall Square - 225 Binney Street 225 Binney Street, 02142 305,212 2013
245 First Street 245 1st Street, 02142 304,889 1900

Largest Office Properties Recently Completed

in East Cambridge

Office building Address Sqft Year built
Cambridge Crossing - Parcel G 350 Water Street, 02141 501,000 2021
Cambridge Crossing - Parcel H 450 Water Street, 02141 405,000 2021
CambridgeSide - 100 Cambridgeside Place Office 100 Cambridgeside Place, 02141 162,000 2021
Cambridge Crossing - JK Site 222 Jacobs Street, 02141 460,000 2020
Akamai Global Headquarters 145 Broadway, 02142 453,768 2019
121 First Street 121 1st Street, 02141 58,200 2019
Alexandria Center at Kendall Square - 50 Binney Street 50 Binney Street, 02142 278,448 2017
Alexandria Center at Kendall Square - 60 Binney Street 60 Binney Street, 02142 262,552 2017
450 Kendall Street 450 Kendall Street, 02142 63,520 2015
Alexandria Center at Kendall Street - 75 Binney Street 75 Binney Street, 02142 144,668 2014