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Middlesex County, MA Office Spaces for Rent - 1,363 Spaces

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  • 481 Main St - Waltham

    481 Main St

    481 Main St, Central Weltham, Waltham, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 1,100 Sqft
    Availability
    • 1 Space
    • 1,100 Sqft
    Year Built
    • 1960
    View Details
  • 490 Broadway - Somerville

    490 Broadway

    490 Broadway, Suite 5, Somerville, MA, Magoun Square, Somerville, MA
    For Lease
    • $900/Sqft/Month
    Property
    • Office
    • 340 Sqft
    Availability
    • 1 Space
    • 340 Sqft
    View Details
  • Cambridge Discovery Park - Buildings 400 & 500 - Cambridge

    Cambridge Discovery Park - Buildings 400 & 500

    100 Acorn Park Drive, North Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 286,000 Sqft
    Availability
    • 1 Space
    • 33,525 Sqft
    Year Built
    • 2020
    View Details
  • Newton Corporate Center - Newton Upper Falls

    Newton Corporate Center

    320 Needham Street, Upper Falls, Newton Upper Falls, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 41,083 Sqft
    Availability
    • 1 Space
    • 20,000 Sqft
    Year Built
    • 1965
    View Details
  • 11 Apex Drive - Marlborough

    11 Apex Drive

    11 Apex Drive, Marlborough, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 111,218 Sqft
    Availability
    • 1 Space
    • 10,000 Sqft
    View Details
  • Greystone Executive Center - Westford

    Greystone Executive Center

    515 Groton Road, Westford, MA
    For Lease
    • $12/Sqft/Year
    Property
    • Office
    • 25,600 Sqft
    Availability
    • 4 Spaces
    • 19,900 Sqft
    Year Built
    • 2000
    View Details
  • 1 JEWEL DRIVE - WILMINGTON

    1 JEWEL DRIVE

    1 JEWEL DRIVE, Wilmington, WILMINGTON, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 175,868 Sqft
    Availability
    • 2 Spaces
    • 27,874 Sqft
    Year Built
    • 1976
    View Details
  • 6 Huron Drive - Natick

    6 Huron Drive

    6 Huron Drive, Natick, MA
    For Lease
    • $17.5/Sqft/Year
    Property
    • Office
    • 28,818 Sqft
    Availability
    • 2 Spaces
    • 2,450 Sqft
    View Details
  • 189 Cambridge Street - Cambridge

    189 Cambridge Street

    189 CAMBRIDGE STREET, East Cambridge, Cambridge, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 8,000 Sqft
    Availability
    • 1 Space
    • 1,000 Sqft
    View Details
  • Lake Williams Corporate Center - V - Marlborough

    Lake Williams Corporate Center - V

    26 Forest Street, Marlborough, MA
    For Lease
    • $20/Sqft/Year
    Property
    • Office
    • 126,000 Sqft
    Availability
    • 1 Space
    • 8,321 Sqft
    Year Built
    • 2001
    View Details
  • 11 Huron Drive - Natick

    11 Huron Drive

    11 Huron Drive, Natick, MA
    For Lease
    • $21/Sqft/Year
    Property
    • Office
    • 30,596 Sqft
    Availability
    • 1 Space
    • 9,909 Sqft
    Year Built
    • 1986
    View Details
  • 77 Main Street - Hopkinton

    77 Main Street

    77 Main Street, Hopkinton, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 55,000 Sqft
    Availability
    • 1 Space
    • 1,096 Sqft
    View Details
  • 74 Main Street - Marlborough

    74 Main Street

    74 Main Street, Marlborough, MA
    For Lease
    • $500/Month
    Property
    • Office
    • 3,048 Sqft
    Availability
    • 1 Space
    • 300 Sqft
    Year Built
    • 1851
    View Details
  • Lincoln Medical Center #203 - Framingham

    Lincoln Medical Center #203

    61 Lincoln Street, Framingham, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 900 Sqft
    Availability
    • 1 Space
    • 900 Sqft
    Year Built
    • 1986
    View Details
  • 25 South Street - Hopkinton

    25 South Street

    25 South Street, Hopkinton, MA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 66,024 Sqft
    Availability
    • 1 Space
    • 3,819 Sqft
    Year Built
    • 1984
    View Details
  • 81 Bridge Street - Lowell

    81 Bridge Street

    81 Bridge Street, Downtown Lowell, Lowell, MA
    For Lease
    • $13/Sqft/Year
    Property
    • Office
    • 33,000 Sqft
    Availability
    • 1 Space
    • 15,500 Sqft
    Year Built
    • 1916
    View Details

Middlesex County, MA Office Inventory Breakdown

Office Spaces

Total: 132,646,044 SF

Data provided by Yardi Matrix, properties over 50k SF, includes office with retail
By square footage range:
50k to 100k SqFt 20,150,377 SqFt 15.19% of total office
100k to 500k SqFt 93,576,282 SqFt 70.55% of total office
500k to 1M SqFt 16,635,385 SqFt 12.54% of total office
> 1M SqFt 2,284,000 SqFt 1.72% of total office
By class:
Class A 51,391,403 SqFt 38.74% of total office
Class B 64,851,376 SqFt 48.89% of total office
Class C 3,755,611 SqFt 2.83% of total office

Top 10 Largest Office Buildings

in Middlesex County

Office building Address Sqft Year built
Mill & Main 146 Main Street, 01754 1,084,000 1998
Partners HealthCare Headquarters 395 Revolution Drive, 02144 850,000 2016
TJX Corporate Headquarters - East Campus - 770 Cochituate Road 770 Cochituate Road, 01701 750,930 1979
Marlborough Hills 200 Forest Street, 01752 741,961 1970
The Center at Innovation Drive 836 North Street, 01876 703,000 1965
One Kendall Square 1 Kendall Square, 02139 669,689 1887
Raytheon Integrated Defense Systems 50 Apple Hill Drive, 01876 652,032 1984
EMC Corporation World Headquarters 176 South Street, 01748 650,000 2001
9/90 Corporate Center - 500 Staples Drive 500 Staples Drive, 01702 650,000 1998
Crosby Corporate Center 32 Crosby Drive, 01730 589,783 1961

Largest Office Properties Recently Completed

in Middlesex County

Office building Address Sqft Year built
Cambridge Crossing - Parcel G 350 Water Street, 02141 501,000 2021
Kendall Square at MIT - 314 Main Street 314 Main Street, 02142 417,000 2021
LabCentral 238 238 Main Street, 02142 414,000 2021
Cambridge Crossing - Parcel H 450 Water Street, 02141 405,000 2021
Assembly Row - 455 Grand Union Blvd 455 Grand Union Blvd, 02145 303,289 2021
Hayden Research Campus - Building IV 75 Hayden Avenue, 02421 214,440 2021
CambridgeSide - 100 Cambridgeside Place Office 100 Cambridgeside Place, 02141 162,000 2021
EMD Serono Research Center - Expansion 45 Middlesex Turnpike, 01821 149,000 2021
Cambridge Crossing - JK Site 222 Jacobs Street, 02141 460,000 2020
Cambridge Discovery Park - Buildings 400 & 500 100 Acorn Park Drive, 02140 286,000 2020