Pacifica Medical Plaza
114 Pacifica, Irvine, CA 92618
27,963
SF Available
Located in the prestigious Irvine Spectrum submarket, Pacifica Medical Plaza offers healthcare providers an exceptional opportunity to establish or expand their practice in one of Orange County’s most sought-after medical office destinations. This distinguished four-story, 114,209-square-foot building delivers a high-image environment designed to meet the expectations of today’s discerning medical tenants and their patients alike.
Benefiting from Irvine Spectrum’s affluent and growing demographics, the property draws a strong and diverse patient base from across the broader Orange County region. Patients consistently seek out this location for access to high-quality medical care, making Pacifica Medical Plaza an ideal setting for providers looking to build a thriving, long-term practice in a premier Southern California healthcare market.
PROMINENT LOCATION & ACCESSIBILITY
The site’s prominent location has high visibility from SR-133 and Irvine Center Drive to create a strong brand image in a proven successful medical market with high growth. Excellent accessibility from 3 major thoroughfares:
• Laguna Freeway (SR-133)
• Santa Ana Freeway (I-5)
• San Diego Freeway (I-405)
MARKET & HOSPITAL PROXIMITY
• The location is able to conveniently serve over 890,000 patients and is growing (within a 15 minute drive time) due to the quality of the roads, major thoroughfares and accessibility of the site
• The service area is expected to grow at a rate of 4% per year
BUILDING HIGHLIGHTS
• Efficient, large open floor plates able to accommodate many specialized medical uses
• Potential to deliver HCAI compliant ground floor
• Full floor opportunity available
• Ground floor availability
HOSPITAL PROXIMITY
• Tenants will find value in the proximity to Hoag Hospital Irvine and Kaiser Permanente Orange County-Irvine Medical Center, located less than 2 miles away. City of Hope’s $1-billion cancer hospital and research center in Irvine is also less than 3 miles away and scheduled for completion in 2025
RECENT RENOVATIONS
• Major capital improvements have been completed including common areas, landscaping, and a new parking structure. New energy efficient systems to keep operating expenses low
• Ownership is committed to enhancing the standard patient and provider experience to create a unique, tranquil building. More upgrades to come!
AMPLE PARKING
• 5.6/1000 parking ratio with both surface and covered parking in the new 3-level garage. Reserved physician parking
• Reserved physician parking
SIGNAGE OPPORTUNITIES
• Eyebrow and monument signages are available with certain suite requirements and restrictions
Rental Details
- Number of spaces 7
- Total square feet available 27,963 SF
- For Lease Contact for pricing
- Space Types Medical Office
- Date Updated Mar 29, 2026
Reach out to the broker for more info on lease terms and amenities
True
For Lease 7 Spaces Available
Suite |
Suite 120 (120/130 are contiguous to 12,631 RSF) • Space Available: 6,815 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 240 (Contiguous up to 5,986 RSF) • Space Available: 2,043 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 250 (Contiguous up to 5,986 RSF) • Space Available: 3,943 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 360 • Space Available: 4,213 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 400 (Contiguous up to 13,562 RSF) • Space Available: 5,944 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 490 (Contiguous up to 13,562 RSF) • Space Available: 7,627 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 330 Spec Plan • Space Available: 1,595 SF • Lease Rate: Call broker for details • Lease Type: Call broker for details • Suite Description: Shell space ready for tenant customization.
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Contacts
MedWest Realty
MedWest Realty
MedWest Realty
Building Details
- For Lease Contact for pricing
- Property Type Office - Medical Office
- Property Size 107,199 SF
- Lot Size 5.11 Acre
- # of Floors 4
- Property Tenancy Multi-Tenant
- Building Class A
- Year Built 1999
- Year Renovated 2021
- Date Updated Mar 29, 2026
Attachments
Getting Around
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Walk Score ®
Car-Dependent (22) -
Transit Score ®
Some Transit (29) -
Bike Score ®
Bikeable (69)
Location
- City Irvine, CA
- Neighborhood Irvine Health And Science Complex
- Zip Code 92618
- Market Orange County
Points of Interest
Tustin Metrolink Station
4.37 miles
Tustin
4.39 miles
Laguna Niguel/Mission Viejo
8.81 miles
Sand Canyon Service Station
1.10 miles
BTCPower
1.30 miles
Arco
1.52 miles
Mobil
1.93 miles
Tesla Supercharger
2.15 miles
Chevron
2.15 miles
Shell
2.77 miles
Circle K
2.96 miles
SemmaConnect
3.42 miles
400 Parking
0.66 miles
200 Parking
0.74 miles
Lot A
0.77 miles
Irvine RV Storage
0.79 miles
P7
0.81 miles
P6
0.83 miles
Lot B
0.86 miles
100 Parking
0.91 miles
Lot C
0.92 miles
Enterprise
2.94 miles
Avis
3.00 miles
The Car Spa
3.60 miles
Culver Auto Spa
4.21 miles
Fast5Xpress Car Wash Irvine
4.73 miles
Manny’s Family Hand Wash
5.06 miles
Harv's Express Car Wash
5.06 miles
Mission Viejo Car Wash
5.10 miles
Cafe Auto Spa
6.04 miles
Wendy's
0.72 miles
Del Taco
0.77 miles
Hi House
0.78 miles
P.F. Chang's
0.78 miles
SAJJ Mediterranean
0.78 miles
Everyday Eatery
0.78 miles
The Flame Broiler
0.79 miles
Grater Grill
0.79 miles
Paul Martin's American Grill
0.80 miles
Nordstrom
1.08 miles
Whole Foods Market
1.18 miles
Target
1.21 miles
Albertsons
1.44 miles
Gelson's
1.97 miles
Ralphs
2.17 miles
99 Ranch Market
2.20 miles
Kohl's
2.50 miles
Trader Joe's
2.65 miles
MedLife Pharmacy & Compounding
0.76 miles
Hoag Hospital Irvine
1.04 miles
OCFA Station 20
1.07 miles
Kaiser Permanente Orange County-Irvine Medical Center
1.15 miles
CVS Pharmacy
1.20 miles
Campus Police
1.43 miles
OCFA Station 51
1.69 miles
OCFA Station 47
1.69 miles
Walgreens
1.89 miles
114 Pacifica Listing Summary
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Office Space Available at 114 Pacifica
Office space currently available at 114 Pacifica adds up to a total of 27,963 square feet across 7 listing(s). The largest individual space listed offers 7,627 square feet. Property use types available for lease at this property include: medical office.
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Learn More about 114 Pacifica
114 Pacifica is located in the Orange County market and pertains to the 92618 zip code. The property incorporates a total of 27,963 square feet of space. 114 Pacifica was built in 1999. The most recent renovation work at this property was completed in 2021.
Interested in researching more about this property? Access in-depth research on 114 Pacifica, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.
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Get to Know the Neighborhood
In the Irvine Health And Science Complex neighborhood, where 114 Pacifica is located, you can currently find 143 office space(s) for rent. In total, this amounts to 1,351,420 square feet of available office space for lease opportunities.