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  1. Office Space
  2. CA
  3. Irvine
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For Lease

Pacifica Medical Plaza

114 Pacifica, Irvine, CA 92618

27,963

SF Available

 

Located in the prestigious Irvine Spectrum submarket, Pacifica Medical Plaza offers healthcare providers an exceptional opportunity to establish or expand their practice in one of Orange County’s most sought-after medical office destinations. This distinguished four-story, 114,209-square-foot building delivers a high-image environment designed to meet the expectations of today’s discerning medical tenants and their patients alike.

 

Benefiting from Irvine Spectrum’s affluent and growing demographics, the property draws a strong and diverse patient base from across the broader Orange County region. Patients consistently seek out this location for access to high-quality medical care, making Pacifica Medical Plaza an ideal setting for providers looking to build a thriving, long-term practice in a premier Southern California healthcare market.

 

 

PROMINENT LOCATION & ACCESSIBILITY

The site’s prominent location has high visibility from SR-133 and Irvine Center Drive to create a strong brand image in a proven successful medical market with high growth. Excellent accessibility from 3 major thoroughfares:

• Laguna Freeway (SR-133)

• Santa Ana Freeway (I-5)

• San Diego Freeway (I-405)

 

MARKET & HOSPITAL PROXIMITY

• The location is able to conveniently serve over 890,000 patients and is growing (within a 15 minute drive time) due to the quality of the roads, major thoroughfares and accessibility of the site

• The service area is expected to grow at a rate of 4% per year

 

BUILDING HIGHLIGHTS

• Efficient, large open floor plates able to accommodate many specialized medical uses

• Potential to deliver HCAI compliant ground floor

• Full floor opportunity available

• Ground floor availability

 

HOSPITAL PROXIMITY

• Tenants will find value in the proximity to Hoag Hospital Irvine and Kaiser Permanente Orange County-Irvine Medical Center, located less than 2 miles away. City of Hope’s $1-billion cancer hospital and research center in Irvine is also less than 3 miles away and scheduled for completion in 2025

 

RECENT RENOVATIONS

• Major capital improvements have been completed including common areas, landscaping, and a new parking structure. New energy efficient systems to keep operating expenses low

• Ownership is committed to enhancing the standard patient and provider experience to create a unique, tranquil building. More upgrades to come!

 

AMPLE PARKING

• 5.6/1000 parking ratio with both surface and covered parking in the new 3-level garage. Reserved physician parking

• Reserved physician parking

 

SIGNAGE OPPORTUNITIES

• Eyebrow and monument signages are available with certain suite requirements and restrictions

 

MORE DETAILS 

 

DOWNLOAD BROCHURE 

 

Rental Details

  • Number of spaces 7
  • Total square feet available 27,963 SF
  • For Lease Contact for pricing
  • Space Types Medical Office
  • Date Updated Mar 29, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

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For Lease 7 Spaces Available

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 2,598 SF
  • Floor 1
  • Available Date Immediate
  • Sublease No
  • Space Number 120

Suite 120 (120/130 are contiguous to 12,631 RSF)

• Space Available: 6,815 SF

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 2,043 SF
  • Floor 2
  • Max Contiguous 5,986 SF
  • Available Date Immediate
  • Sublease No
  • Space Number 240

Suite 240 (Contiguous up to 5,986 RSF)

• Space Available: 2,043 SF 

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 3,943 SF
  • Floor 2
  • Max Contiguous 5,986 SF
  • Available Date Immediate
  • Sublease No
  • Space Number 250

Suite 250 (Contiguous up to 5,986 RSF)

• Space Available: 3,943 SF 

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 4,213 SF
  • Floor 3
  • Available Date Immediate
  • Sublease No
  • Space Number 360

Suite 360

• Space Available: 4,213 SF

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 5,944 SF
  • Floor 4
  • Max Contiguous 13,562 SF
  • Available Date Immediate
  • Sublease No
  • Space Number 400

Suite 400 (Contiguous up to 13,562 RSF)

• Space Available: 5,944 SF

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 7,627 SF
  • Floor 4
  • Max Contiguous 13,562 SF
  • Available Date Immediate
  • Sublease No
  • Space Number 490

Suite 490 (Contiguous up to 13,562 RSF)

• Space Available: 7,627 SF

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Suite

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 1,595 SF
  • Floor 3
  • Available Date Immediate
  • Sublease No
  • Space Number 330

Suite 330 Spec Plan

• Space Available: 1,595 SF

• Lease Rate: Call broker for details

• Lease Type: Call broker for details

• Suite Description: Shell space ready for tenant customization.

 

Contacts

broker
Casey Immel

MedWest Realty

broker
Kellie Hill

MedWest Realty

broker
Stacey Hall

MedWest Realty

Building Details

  • For Lease Contact for pricing
  • Property Type Office - Medical Office
  • Property Size 107,199 SF
  • Lot Size 5.11 Acre
  • # of Floors 4
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 1999
  • Year Renovated 2021
  • Date Updated Mar 29, 2026

Attachments

  • Floor Plans (PDF) opens in new window
  • Lease Brochure (PDF) opens in new window

Getting Around

  • Walk Score ®

    Car-Dependent (22)
  • Transit Score ®

    Some Transit (29)
  • Bike Score ®

    Bikeable (69)
Powered by Walk Score ®

Location

  • City Irvine, CA
  • Neighborhood Irvine Health And Science Complex
  • Zip Code 92618
  • Market Orange County
  • Map
  • Street

Points of Interest

Tustin Metrolink Station

4.37 miles

Tustin

4.39 miles

Laguna Niguel/Mission Viejo

8.81 miles

Sand Canyon Service Station

1.10 miles

BTCPower

1.30 miles

Arco

1.52 miles

Mobil

1.93 miles

Tesla Supercharger

2.15 miles

Chevron

2.15 miles

Shell

2.77 miles

Circle K

2.96 miles

SemmaConnect

3.42 miles

400 Parking

0.66 miles

200 Parking

0.74 miles

Lot A

0.77 miles

Irvine RV Storage

0.79 miles

P7

0.81 miles

P6

0.83 miles

Lot B

0.86 miles

100 Parking

0.91 miles

Lot C

0.92 miles

Enterprise

2.94 miles

Avis

3.00 miles

The Car Spa

3.60 miles

Culver Auto Spa

4.21 miles

Fast5Xpress Car Wash Irvine

4.73 miles

Manny’s Family Hand Wash

5.06 miles

Harv's Express Car Wash

5.06 miles

Mission Viejo Car Wash

5.10 miles

Cafe Auto Spa

6.04 miles

Wendy's

0.72 miles

Del Taco

0.77 miles

Hi House

0.78 miles

P.F. Chang's

0.78 miles

SAJJ Mediterranean

0.78 miles

Everyday Eatery

0.78 miles

The Flame Broiler

0.79 miles

Grater Grill

0.79 miles

Paul Martin's American Grill

0.80 miles

Nordstrom

1.08 miles

Whole Foods Market

1.18 miles

Target

1.21 miles

Albertsons

1.44 miles

Gelson's

1.97 miles

Ralphs

2.17 miles

99 Ranch Market

2.20 miles

Kohl's

2.50 miles

Trader Joe's

2.65 miles

MedLife Pharmacy & Compounding

0.76 miles

Hoag Hospital Irvine

1.04 miles

OCFA Station 20

1.07 miles

Kaiser Permanente Orange County-Irvine Medical Center

1.15 miles

CVS Pharmacy

1.20 miles

Campus Police

1.43 miles

OCFA Station 51

1.69 miles

OCFA Station 47

1.69 miles

Walgreens

1.89 miles

114 Pacifica Listing Summary

  • Office Space Available at 114 Pacifica

    Office space currently available at 114 Pacifica adds up to a total of 27,963 square feet across 7 listing(s). The largest individual space listed offers 7,627 square feet. Property use types available for lease at this property include: medical office.

  • Learn More about 114 Pacifica

    114 Pacifica is located in the Orange County market and pertains to the 92618 zip code. The property incorporates a total of 27,963 square feet of space. 114 Pacifica was built in 1999. The most recent renovation work at this property was completed in 2021.

    Interested in researching more about this property? Access in-depth research on 114 Pacifica, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Irvine Health And Science Complex neighborhood, where 114 Pacifica is located, you can currently find 143 office space(s) for rent. In total, this amounts to 1,351,420 square feet of available office space for lease opportunities.

Contact Pacifica Medical Plaza
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