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  1. Office Space
  2. CA
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For Lease

20/6 - Six

450 B St., San Diego, CA 92101

66,569

SF Available

Rental Details

  • Number of spaces 7
  • Total square feet available 66,569 SF
  • For Lease Contact for pricing
  • Space Types General Office
  • Lease Type Full Service
  • Date Updated May 22, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 7 Spaces Available

Suite 200

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 4,842 SF
  • Floor 2
  • Divisible Space 4,842 - 4,842 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 200
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 225

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,877 SF
  • Floor 2
  • Divisible Space 2,877 - 2,877 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 225
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 250

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 6,200 SF
  • Floor 2
  • Divisible Space 6,200 - 6,200 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 250
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 325/350

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 6,765 SF
  • Floor 3
  • Divisible Space 1,180 - 6,765 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 325/350
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 400

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 15,272 SF
  • Floor 4
  • Divisible Space 15,272 - 15,272 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 400
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 500

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 15,289 SF
  • Floor 5
  • Divisible Space 15,289 - 15,289 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 500
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 600

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 15,324 SF
  • Floor 6
  • Divisible Space 15,324 - 15,324 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 600
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Contacts

broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Building Details

  • For Lease Contact for pricing
  • Property Type Office
  • Property Size 91,546 SF
  • # of Floors 6
  • Parking Ratio 1.10 / 1,000 SF
  • Building Class A
  • Year Built 2021
  • Date Updated May 22, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (100)
  • Transit Score ®

    Excellent Transit (81)
  • Bike Score ®

    Very Bikeable (80)
Powered by Walk Score ®

Location

  • City San Diego, CA
  • Neighborhood Core - Columbia
  • Zip Code 92101
  • Market San Diego
  • Map
  • Street

Points of Interest

Courthouse

0.32 miles

City College

0.39 miles

Santa Fe Depot

0.54 miles

County Center/Little Italy

0.59 miles

Seaport Village

0.63 miles

Park & Market

0.63 miles

Gaslamp Quarter

0.78 miles

25th/Commercial

1.48 miles

Barrio Logan

1.60 miles

San Diego - A Street Supercharger

0.10 miles

Shell

0.32 miles

Chevron

0.38 miles

ChargePoint Charging Station

0.58 miles

Petromerica

0.69 miles

Arco

0.78 miles

Mobil

0.79 miles

Top tier Gasoline

0.80 miles

Valero

1.08 miles

U.S. Grant Hotel Parking

0.13 miles

Ace Parking Lot

0.14 miles

Toussaint Academy San Diego Parking Lot

0.15 miles

Evan V. Jones Parkade

0.16 miles

Stock Exchange Sq

0.17 miles

free public parking

0.22 miles

Laz Parking Garage

0.28 miles

Ace Parking

0.33 miles

Best Western Plus Bayside Inn Parking

0.44 miles

Avis

0.60 miles

Car Rental desk

0.70 miles

West Coast Rent-a-Car

0.75 miles

AVR Van Rental

0.79 miles

Fox Rent a Car

1.20 miles

Alamo San Diego Intl Arpt/Shuttle

1.34 miles

Thrifty

1.71 miles

SIXT Rent a Car San Diego Int Airport

1.72 miles

Green Go Wash Professional Auto Detailing and Car Wash

3.58 miles

BB's Deli

0.09 miles

City Pizzeria

0.09 miles

Valentine's

0.10 miles

Al Teatro Panini Grill

0.10 miles

Thotsakan

0.10 miles

Med Cafe

0.10 miles

Swami's Cafe

0.10 miles

Pho Express

0.10 miles

Donut Bar

0.11 miles

Ralphs

0.45 miles

The Market By Buon Appetito

0.52 miles

Grocery Outlet

0.54 miles

Smart & Final

0.67 miles

Albertsons

0.69 miles

Little Brazil Market

0.72 miles

Assenti's Pasta

0.75 miles

Mona Lisa

0.75 miles

Walmart Neighborhood Market

1.27 miles

CVS Pharmacy

0.09 miles

San Diego Fire-Rescue Department Station No. 1

0.23 miles

Rite Aid

0.51 miles

San Diego Police Department Headquarters

0.60 miles

San Diego Fire Station Number 4

0.61 miles

Fire Station 3

0.93 miles

Naval Medical Center San Diego

1.01 miles

San Diego American Indian Health Center

1.05 miles

San Diego City Fire Station #11

1.21 miles

450 B St. Listing Summary

  • Office Space Available at 450 B St.

    Office space currently available at 450 B St. adds up to a total of 66,569 square feet across 7 listing(s). The largest individual space listed offers 15,324 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 450 B St.

    450 B St. is located in the San Diego market and pertains to the 92101 zip code. The property incorporates a total of 66,569 square feet of space. 450 B St. features a parking ratio of 1.10 / 1,000 SF, offering a total of 101 parking spaces. 450 B St. was built in 2021.

    Interested in researching more about this property? Access in-depth research on 450 B St., including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Core - Columbia neighborhood, where 450 B St. is located, you can currently find 290 office space(s) for rent. In total, this amounts to 2,020,212 square feet of available office space for lease opportunities.

Contact 20/6 - Six
  1. 1Main information
  2. 2Extra information
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