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For Lease

20/6 - Twenty

451 A St., San Diego, CA 92101

67,770

SF Available

Key features

  • Banking
  • Conferencing Facility
  • Controlled Access
  • Property Manager on Site
  • Security System
  • Signage

Rental Details

  • Number of spaces 11
  • Total square feet available 67,770 SF
  • For Lease Contact for pricing
  • Space Types General Office
  • Lease Type Full Service
  • Date Updated May 20, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 11 Spaces Available

Suite 1500

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 14,429 SF
  • Floor 15
  • Divisible Space 14,429 - 14,429 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 1500
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 1900

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 14,025 SF
  • Floor 19
  • Divisible Space 14,025 - 14,025 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 1900
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 2000

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 15,315 SF
  • Floor 20
  • Divisible Space 15,315 - 15,315 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 2000
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 600

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,869 SF
  • Floor 6
  • Divisible Space 2,869 - 2,869 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 600
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 610

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,412 SF
  • Floor 6
  • Divisible Space 2,412 - 2,412 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 610
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 620

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 1,921 SF
  • Floor 6
  • Divisible Space 1,921 - 1,921 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 620
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 650

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 5,962 SF
  • Floor 6
  • Divisible Space 5,962 - 5,962 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 650
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 720

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,445 SF
  • Floor 7
  • Divisible Space 2,445 - 2,445 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 720
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 740

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 3,205 SF
  • Floor 7
  • Divisible Space 3,205 - 3,205 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 740
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 750

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,791 SF
  • Floor 7
  • Divisible Space 2,791 - 2,791 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 750
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Suite 780

  • Space Type General Office
  • Lease Rate Negotiable
  • Total Space Available 2,396 SF
  • Floor 7
  • Divisible Space 2,396 - 2,396 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
  • Space Number 780
broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Contacts

broker
Derek Hulse

Cushman & Wakefield

broker
Connor Wieck

Cushman & Wakefield

Building Details

  • For Lease Contact for pricing
  • Property Type Office
  • Property Size 309,947 SF
  • # of Floors 19
  • Parking Ratio 1.10 / 1,000 SF
  • Building Class B
  • Year Built 1982
  • Date Updated May 20, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (100)
  • Transit Score ®

    Excellent Transit (81)
  • Bike Score ®

    Very Bikeable (80)
Powered by Walk Score ®

Location

  • City San Diego, CA
  • Neighborhood Core - Columbia
  • Zip Code 92101
  • Market San Diego
  • Map
  • Street

Points of Interest

Courthouse

0.32 miles

City College

0.41 miles

Santa Fe Depot

0.54 miles

County Center/Little Italy

0.57 miles

Seaport Village

0.64 miles

Park & Market

0.65 miles

Gaslamp Quarter

0.79 miles

25th/Commercial

1.50 miles

Barrio Logan

1.62 miles

San Diego - A Street Supercharger

0.09 miles

Shell

0.33 miles

Chevron

0.36 miles

ChargePoint Charging Station

0.56 miles

Petromerica

0.71 miles

Mobil

0.78 miles

Arco

0.79 miles

Top tier Gasoline

0.82 miles

Valero

1.06 miles

Ace Parking Lot

0.12 miles

Toussaint Academy San Diego Parking Lot

0.13 miles

U.S. Grant Hotel Parking

0.14 miles

Stock Exchange Sq

0.15 miles

Evan V. Jones Parkade

0.15 miles

free public parking

0.23 miles

Laz Parking Garage

0.26 miles

Ace Parking

0.34 miles

Best Western Plus Bayside Inn Parking

0.43 miles

Avis

0.58 miles

Car Rental desk

0.71 miles

West Coast Rent-a-Car

0.73 miles

AVR Van Rental

0.77 miles

Fox Rent a Car

1.18 miles

Alamo San Diego Intl Arpt/Shuttle

1.32 miles

Thrifty

1.69 miles

SIXT Rent a Car San Diego Int Airport

1.70 miles

Green Go Wash Professional Auto Detailing and Car Wash

3.56 miles

Al Teatro Panini Grill

0.08 miles

Med Cafe

0.09 miles

Cafe De L'Opera

0.09 miles

McCozy

0.10 miles

City Pizzeria

0.11 miles

Valentine's

0.11 miles

Thotsakan

0.11 miles

Swami's Cafe

0.12 miles

Pho Express

0.12 miles

Ralphs

0.46 miles

The Market By Buon Appetito

0.50 miles

Grocery Outlet

0.56 miles

Smart & Final

0.68 miles

Little Brazil Market

0.71 miles

Albertsons

0.71 miles

Assenti's Pasta

0.73 miles

Mona Lisa

0.73 miles

Walmart Neighborhood Market

1.29 miles

CVS Pharmacy

0.11 miles

San Diego Fire-Rescue Department Station No. 1

0.22 miles

Rite Aid

0.49 miles

San Diego Police Department Headquarters

0.61 miles

San Diego Fire Station Number 4

0.63 miles

Fire Station 3

0.91 miles

Naval Medical Center San Diego

1.01 miles

San Diego American Indian Health Center

1.03 miles

San Diego City Fire Station #11

1.23 miles

451 A St. Listing Summary

  • Office Space Available at 451 A St.

    Office space currently available at 451 A St. adds up to a total of 67,770 square feet across 11 listing(s). The largest individual space listed offers 15,315 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 451 A St.

    451 A St. is located in the San Diego market and pertains to the 92101 zip code. The property incorporates a total of 67,770 square feet of space. 451 A St. features a parking ratio of 1.10 / 1,000 SF, offering a total of 341 parking spaces. 451 A St. was built in 1982.

    Interested in researching more about this property? Access in-depth research on 451 A St., including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Core - Columbia neighborhood, where 451 A St. is located, you can currently find 290 office space(s) for rent. In total, this amounts to 2,020,212 square feet of available office space for lease opportunities.

Contact 20/6 - Twenty
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