221 Main
221 Main Street, San Francisco, CA 94105
Rental Details
- Number of spaces 2
- Total square feet available 16,114 SF
- For Lease Price on request
- Space Type General Office, Creative Office
- Latest Update Aug 25, 2026
Reach out to the broker for more info on lease terms and amenities
True
2 Spaces Available
| Space Name | Space Type | Lease Rate | Total Space | Floor | Lease Type | |
|---|---|---|---|---|---|---|
| #1650 | General Office | Price on request | 12,012 SF | 16 | - | |
| #400 | Creative Office | Price on request | 4,102 SF | 4 | - |
#1650
- Space Type
- General Office
- Lease Rate
- Price on request
- Total Space
- 12,012 SF
- Floor
- 16
#400
- Space Type
- Creative Office
- Lease Rate
- Price on request
- Total Space
- 4,102 SF
- Floor
- 4
Contacts
Jones Lang LaSalle
Jones Lang LaSalle
Jones Lang LaSalle
Jones Lang LaSalle
Jones Lang LaSalle
Building Details
- For Lease Price on request
- Property Type Office - General Office
- Property Size 387,943 SF
- Lot Size 1.08 Acre
- Additional Rent Price on request
- Parking Spaces Avail. 108
- Parking Ratio 0.28 / 1,000 SF
- Property Tenancy Multi-Tenant
- LEED Certified Platinum
- Building Class A
- Year Built 1973
- Date Updated Aug 25, 2026
Location
- City San Francisco, CA
- Neighborhood South Beach
- Zip Code 94105
- Market San Francisco
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Walk score 97/100 Walker's Paradise -
Transit score 100/100 Rider's Paradise -
Bike score 80/100 Very Bikeable
Points of Interest
Taxi Stand at Hotel Vitale
0.23 miles
Taxi Stand at Farmers Market near Ferry Building
0.23 miles
Taxi Stand at Salesforce Transit Center
0.27 miles
Market Street & Drumm Street
0.31 miles
Market Street & Main Street
0.31 miles
California Street & Drumm Street
0.33 miles
Taxi Stand at 101 California St Building (along Davis St)
0.35 miles
Taxi Stand at Hyatt Regency (along Drumm St)
0.36 miles
California Street & Davis Street
0.38 miles
Market Street & Battery Street
0.38 miles
Shell
0.69 miles
Chevron
1.14 miles
EVgo
1.50 miles
Volta HQ Charging Station
1.62 miles
76
1.64 miles
Standard
1.67 miles
Tesla Destination Charger
2.04 miles
Arco
2.16 miles
Electrify America
2.19 miles
Rivian Waypoints
2.27 miles
201 Spear Upper Lot
0.07 miles
ace parking
0.50 miles
Palace Garage
0.51 miles
Embarcadero Center 1 Parking
0.53 miles
SFMOMA Garage
0.53 miles
Golden Gateway Garage
0.54 miles
Moscone Center Garage
0.56 miles
550 California Street Parking Garage
0.66 miles
Jessie Square Garage
0.68 miles
The White House Garage
0.68 miles
Alamo/Enterprise/National
0.56 miles
Zipcar
0.80 miles
Getaround
0.80 miles
City Car Share
0.80 miles
Avis
0.80 miles
Budget
0.80 miles
Alamo
0.96 miles
Hertz
1.01 miles
National & Alamo
1.03 miles
Thrifty
1.05 miles
Sweetgreen
0.06 miles
Prospect
0.07 miles
Proper Food
0.08 miles
Mau
0.09 miles
SOMA Eats
0.10 miles
Nick The Greek
0.11 miles
Tokyo Express
0.12 miles
Epic Steak
0.15 miles
Ozumo
0.16 miles
Waterbar
0.16 miles
Woodlands Market
0.10 miles
Safeway
0.57 miles
Chaat Corner Indian Grocery
0.60 miles
Crocker Galleria
0.60 miles
Metreon
0.74 miles
Target
0.75 miles
Whole Foods Market
0.77 miles
Neiman Marcus
0.77 miles
Ross
0.80 miles
Trader Joe's
0.82 miles
Security Office
0.08 miles
Spring Fertility
0.19 miles
San Francisco Fire Station 35
0.20 miles
Walgreens
0.30 miles
Concentra Urgent Care
0.36 miles
Care Essentials
0.39 miles
Focus Clinic
0.52 miles
San Francisco VA Medical Center - Downtown Clinic
0.61 miles
San Francisco Fire Station 13
0.62 miles
One Medical
0.66 miles
Listing Summary
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Office Space Available at 221 Main Street
Office space currently available at 221 Main Street adds up to a total of 16,114 square feet across 2 listing(s). The largest individual space listed offers 12,012 square feet. Property use types available for lease at this property include: general office and creative office.
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Learn More about 221 Main Street
221 Main Street is located in the San Francisco market and pertains to the 94105 zip code. The property incorporates a total of 16,114 square feet of space. 221 Main Street features a parking ratio of 0.28 / 1,000 SF, offering a total of 108 parking spaces. 221 Main Street was built in 1973.
Interested in researching more about this property? Access in-depth research on 221 Main Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.
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Get to Know the Neighborhood
In the South Beach neighborhood, where 221 Main Street is located, you can currently find 168 office space(s) for rent. In total, this amounts to 3,522,642 square feet of available office space for lease opportunities.
