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  1. Office Space
  2. CA
  3. San Francisco
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For Lease

501 Second Street

501 2nd Street, San Francisco, CA 94107

10,493

SF Available

Rental Details

  • Number of spaces 2
  • Total square feet available 10,493 SF
  • For Lease Contact for pricing
  • Space Types Creative Office
  • Date Updated Apr 7, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 2 Spaces Available

#415

  • Space Type Creative Office
  • Lease Rate Contact for pricing
  • Total Space Available 4,852 SF
  • Divisible Space 4,852 - 4,852 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

• 4,852 SF\n• 8 exam rooms, with exam tables\n• 2 conference rooms\n• Kitchen and staff room\n• 2 private offices\n• 2 private restrooms

broker
Michael McCarthy

Transwestern

broker
Brian McCarthy

Transwestern

broker
Madeline Meyersieck

Transwestern

#625

  • Space Type Creative Office
  • Lease Rate Contact for pricing
  • Total Space Available 5,641 SF
  • Divisible Space 5,641 - 5,641 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No
broker
Michael McCarthy

Transwestern

broker
Brian McCarthy

Transwestern

broker
Madeline Meyersieck

Transwestern

Contacts

broker
Michael McCarthy

Transwestern

broker
Brian McCarthy

Transwestern

broker
Madeline Meyersieck

Transwestern

Building Details

  • For Lease Contact for pricing
  • Property Type Office - Creative Office
  • Property Size 207,809 SF
  • Lot Size 0.95 Acre
  • Parking Spaces Avail. 81
  • Parking Ratio 0.39 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • LEED Certified Platinum
  • Building Class A
  • Year Built 1925
  • Date Updated Apr 7, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (94)
  • Transit Score ®

    Rider's Paradise (100)
  • Bike Score ®

    Very Bikeable (79)
Powered by Walk Score ®

Location

  • City San Francisco, CA
  • Neighborhood South Beach
  • Zip Code 94107
  • Market San Francisco
  • Map
  • Street

Points of Interest

Taxi Stand at Courtyard by Marriot SF Downtown

0.28 miles

Brannan

0.28 miles

2nd & King

0.31 miles

Fourth/Brannan

0.37 miles

Moscone Center

0.40 miles

Taxi Stand at W San Francisco (along Howard St)

0.40 miles

Taxi Stand at Salesforce Transit Center

0.43 miles

Taxi Stand at Caltrain Station at 4th and King St

0.44 miles

Yerba Buena/Moscone

0.46 miles

Chevron

0.74 miles

Volta HQ Charging Station

1.13 miles

EVgo

1.29 miles

76

1.50 miles

Standard

1.66 miles

Arco

1.79 miles

Dogpatch Biofuels

1.84 miles

Tesla Destination Charger

1.95 miles

Electrify America

2.08 miles

Fan Lot

0.39 miles

SFMOMA Garage

0.45 miles

Palace Garage

0.56 miles

201 Spear Upper Lot

0.58 miles

Jessie Square Garage

0.59 miles

Marriott Valet Parking Entrance

0.59 miles

Four Seasons Valet Parking Entrance

0.62 miles

Pier 48

0.63 miles

5th and Mission Garage

0.64 miles

Avis

0.54 miles

Budget

0.54 miles

Getaround

0.88 miles

City Car Share

0.88 miles

Zipcar

0.88 miles

Enterprise

0.93 miles

Hertz

0.94 miles

National & Alamo

0.95 miles

Thrifty

0.97 miles

Caffe Centro

0.11 miles

South Park Cafe

0.12 miles

Rooh

0.14 miles

SAJJ Mediterranean

0.15 miles

Curry & Kabab

0.18 miles

Soma Pizza

0.18 miles

Garaje

0.18 miles

Rooster & Rice

0.20 miles

Slice House

0.20 miles

Whole Foods Market

0.38 miles

Woodlands Market

0.42 miles

Safeway

0.44 miles

Metreon

0.53 miles

Target

0.58 miles

Gus's Community Market

0.62 miles

Bloomingdale's

0.68 miles

Ross

0.69 miles

Trader Joe's

0.69 miles

Seafarers’ Medical Center

0.29 miles

South of Market Mental Health Center

0.32 miles

Saint Francis Health Center

0.43 miles

Walgreens

0.43 miles

Care Essentials

0.43 miles

San Francisco Fire Station 8

0.44 miles

Security Office

0.48 miles

Spring Fertility

0.51 miles

San Francisco Fire Station 35

0.56 miles

501 2nd Street Listing Summary

  • Office Space Available at 501 2nd Street

    Office space currently available at 501 2nd Street adds up to a total of 10,493 square feet across 2 listing(s). The largest individual space listed offers 5,641 square feet. Property use types available for lease at this property include: creative office.

  • Learn More about 501 2nd Street

    501 2nd Street is located in the San Francisco market and pertains to the 94107 zip code. The property incorporates a total of 10,493 square feet of space. 501 2nd Street features a parking ratio of 0.39 / 1,000 SF, offering a total of 81 parking spaces. 501 2nd Street was built in 1925.

    Interested in researching more about this property? Access in-depth research on 501 2nd Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the South Beach neighborhood, where 501 2nd Street is located, you can currently find 173 office space(s) for rent. In total, this amounts to 3,242,211 square feet of available office space for lease opportunities.

Contact 501 Second Street
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