• Resources
    • Learning Center
    • Blog
Add a Listing Advertise
  • Property Lists
  • Listings
    • Commercial Real Estate
  • Foreclosures
    • New York City Pre-Foreclosures
    • New York City Foreclosures
    • New York City Auction Results
    • New York City Bank Owned (REO)
  • Comparables
  • Owners
  • Maps
  1. Commercial Spaces
  2. NY
  3. New York City
  4. Manhattan
  • Details
  • Spaces Available
  • Contacts
  • Location
  • POI
  • eBrochure
For Lease

208 E 75th St

208 E 75th St, New York, NY 10021

900

SF Available

Prime Upper East Side Maisonette Medical/Professional Suite 

 

Situated in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners, wellness professionals, and non-profit institutions. Occupying the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street level, offering an ideal balance of street-level accessibility and user privacy.

 

The entire ground floor has undergone a complete, high-end renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas that requires zero structural work for open-plan tenants, while remaining highly adaptable for clinical division.

 

Versatile Layout Potential: Immediate Turnkey Open Concept or Seamless Medical Build-Out

 

For practices requiring a traditional multi-room clinical environment, the generous footprint easily configures into a highly efficient, multi-operatory floor plan. The space can seamlessly accommodate:

- A spacious, welcoming patient reception and check-in lobby directly off the entryway foyer.

- A dedicated administrative and billing hub with an integrated communication window.

- Multiple private examination rooms or clinical operatories.

- A separate, expansive doctor’s executive consultation suite.

- A staff kitchen/break area and localized storage hubs.

 

The property's flexible layout and Group 3 zoning make it ideal for a wide variety of professional organizations, including:

 

Medical & Clinical Practices: Perfect for private medical practices, dental clinics, dermatology, and multi-provider medical groups.

Outpatient & Wellness Centers: Exceptionally well-suited for sports physical therapy, chiropractic care, acupuncture collectives, and holistic health centers that benefit from the open-concept layout.

Private Consultation & Mental Health Suites: Ideal for psychiatrists, psychologists, speech therapists, and counselors seeking a highly private, quiet, and discreet environment with a dedicated street entrance.

Creative & Cultural Non-Profit Foundations: The pristine open layout is a flawless match for 501(c)(3) non-commercial art galleries, foundations, literary societies, historical archives, or boutique reading rooms.

Educational & Philanthropic Institutions: Highly adaptable for boutique specialized schools, STEM learning labs, private tutoring networks, or administrative headquarters for philanthropic organizations.

 

Located in one of Manhattan’s most pedestrian-friendly and affluent residential enclaves, your space is surrounded by premium retail, fine dining, and neighborhood amenities. Transit options are exceptionally convenient for both staff and clients, with immediate access to Third and Lexington Avenue subway lines (Q and 6 trains) and cross-town bus routes.

Rental Details

  • Number of spaces 1
  • Total square feet available 900 SF
  • For Lease $6,250.00/MO
  • Space Types Medical Office
  • Lease Type Modified Gross
  • Date Updated Jun 9, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

Prime Garden Level Medical/Professional Suite

  • Space Type Medical Office
  • Lease Rate $6,250.00/MO
  • Total Space Available 900 SF
  • Attachments png opens in new window pdf opens in new window png opens in new window
  • Photos
  • Additional Space Types Creative, Office Condo, Institutional/Governmental
  • Floor ground floor
  • Divisible Space 900 - 900 SF
  • Available Date Immediate
  • Lease Type Modified Gross
  • Lease Term From 1 To 10 Years
  • Renewal Option Yes
  • Sublease No
  • Build Type Partial build out

Positioned in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners and wellness professionals. Situated on the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street scale, offering an ideal balance of street-level accessibility and patient privacy. 

The entire ground floor has undergone a complete renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas for standard professional offices, physical therapy practices, or holistic health centers. 

The space can seamlessly accommodate:

  • A spacious, welcoming patient reception and check-in lobby directly off the foyer.
  • A dedicated administrative and billing hub
  • Multiple private examination rooms or clinical operatories.
  • A separate, expansive doctor’s executive consultation suite.
  • A large staff kitchen area and localized storage hubs.

Amenities

  • Private street entrance steps off Third Avenue
  • 2026 Renovation
  • Brand new hard wood floors
  • Two working fireplaces
  • Brand new bathroom
  • Shared outdoor garden access

Contacts

broker
Alexandru Galiceanu

Lexington Real Estate Group

Principal Broker

Building Details

  • For Lease $6,250.00/MO
  • Property Type Multi-Family
  • Property Size 5,300 SF
  • Units 4
  • Lot Size 0.05 Acre
  • Zoning R8B
  • # of Floors 5
  • Average Floor Size 950 SF
  • Property Tenancy Single Tenant
  • Building Class B
  • Year Built 1910
  • Year Renovated 2026
  • Date Updated Jun 9, 2026

Attachments

  • Listing Brochure (PDF) opens in new window

Getting Around

  • Walk Score ®

    Walker's Paradise (99)
  • Transit Score ®

    Rider's Paradise (100)
  • Bike Score ®

    Very Bikeable (83)
Powered by Walk Score ®

Location

  • City New York, NY
  • Neighborhood Lenox Hill
  • Zip Code 10021
  • Market Manhattan
  • Map
  • Street

Points of Interest

East 77th Street & Lexington Avenue at Southeast Corner

0.17 miles

East 77th Street & Lexington Avenue at Northeast Corner

0.17 miles

77th Street

0.18 miles

East 77th Street & Lexington Avenue at Southwest Corner

0.18 miles

East 77th Street & Lexington Avenue at Northwest Corner

0.19 miles

72nd Street & 2nd Avenue at Southeast Corner

0.19 miles

East 68th Street & Lexington Avenue at Northeast Corner

0.36 miles

East 68th Street & Lexington Avenue at Northwest Corner

0.36 miles

68th Street–Hunter College

0.37 miles

plugNYC

0.82 miles

Shell

1.08 miles

BP

1.38 miles

Citgo

1.38 miles

Atlantic

1.43 miles

Mobil

1.48 miles

Sunoco

1.52 miles

Surrey Garage

0.36 miles

Metropolitan Museum

0.53 miles

Loeb Boathouse Parking Lot

0.58 miles

Quik Park

0.67 miles

Motorgate Public Parking Garage

0.78 miles

Knickerbocker Plaza Car Park

0.87 miles

Astor Terrace Parking Garage

0.96 miles

Central Parking

1.11 miles

Alpha Garage

1.12 miles

Thrifty

0.43 miles

Budget

0.63 miles

Enterprise CarShare

1.04 miles

Avis

1.26 miles

Queensboro Car Wash

1.38 miles

Cheap Car Lease NYC

1.61 miles

Mizuma International Inc.

1.81 miles

Zipcar

2.20 miles

Hand Car Wash Detailing

3.20 miles

Sashimi Express II

0.04 miles

Juice Press

0.06 miles

B. Cafe

0.06 miles

Tangs

0.07 miles

EJ's Luncheonette

0.08 miles

Seamore's

0.08 miles

Tabata Ramen & Yakitori Bar

0.09 miles

Dunkin'

0.09 miles

THEP

0.09 miles

Gristedes

0.11 miles

Morton Williams

0.13 miles

D'Agostino

0.15 miles

Daona Market Place

0.25 miles

Target

0.26 miles

A Matter of Health

0.26 miles

Whole Foods Market

0.32 miles

Agatha & Valentina

0.32 miles

Ouri's Market

0.36 miles

New Drug Loft

0.13 miles

Value Price Pharmacy

0.13 miles

Duane Reade

0.16 miles

CVS Pharmacy

0.17 miles

VRMED

0.17 miles

Lenox Hill Hospital

0.20 miles

ThrIVewell Infusion

0.24 miles

Walgreens

0.26 miles

CityMD

0.26 miles

208 E 75th St Listing Summary

  • What is the asking price at 208 E 75th St?

    The asking price for spaces at 208 E 75th St rests at $6,250.00/MO.

  • How many office spaces for rent are listed at 208 E 75th St?

    1 office space is listed at 208 E 75th St.

  • What is the total size of 208 E 75th St?

    208 E 75th St has a total of 5,300 square feet.

  • What is the year built for 208 E 75th St?

    The year built for 208 E 75th St is 1910.

Contact Listing Broker
broker
Alexandru Galiceanu

Lexington Real Estate Group

Principal Broker

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Nearby Listings

242 West 53rd Street

242 West 53rd Street

242 West 53rd Street, New York, NY
Contact for pricing
Property
  • Multi-Family
  • 542,276 SF
Availability
  • 1 Space
  • 3,870 SF
693 9th Ave

693 9th Ave

693 9th Ave, New York, NY
Contact for pricing
Property
  • Multi-Family
  • 9,744 SF
Availability
  • 1 Space
  • 925 SF
606 W 57th St

606 W 57th St

606 W 57th St, New York, NY
Contact for pricing
Property
  • Multi-Family
  • 952,938 SF
Availability
  • 1 Space
  • 11,486 SF
210 E 122nd St

210 E 122nd St

210 E 122nd St, New York, NY
$43.64/SF/YR
Property
  • Multi-Family
  • 5,378 SF
Availability
  • 1 Space
  • 2,200 SF
68 East 131st Street

68 East 131st Street

68 East 131st Street, New York, NY
$2,205.00 - $5,020.00/MO
Property
  • Multi-Family
  • 33,515 SF
Availability
  • 2 Spaces
  • 2,015 SF

Popular Searches

  • New York City Office Space for Rent
  • Manhattan Office Space for Rent
  • Brooklyn Office Space for Rent
  • Hudson Valley Office Space for Rent
  • Queens Office Space for Rent
  • Philadelphia Office Space for Rent
  • Bronx Office Space for Rent
  • Stamford Office Space for Rent
  • Princeton Office Space for Rent
  • Melville Office Space for Rent
  • New York City Commercial Real Estate
  • Brooklyn Commercial Real Estate
  • Queens Commercial Real Estate
  • Manhattan Commercial Real Estate
  • Hudson Valley Commercial Real Estate
  • Philadelphia Commercial Real Estate
  • Bronx Commercial Real Estate
  • Newark Commercial Real Estate
  • Yonkers Commercial Real Estate
  • Bridgeport Commercial Real Estate
Copyright 2003-2026, PropertyShark.com
Contact Us  |  About  |  Privacy Policy  |  Terms Of Service  |  Sitemaps