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208 E 75th St

For Lease 900 SF

208 E 75th St, New York, NY 10021

Prime Upper East Side Maisonette Medical/Professional Suite 

 

Situated in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners, wellness professionals, and non-profit institutions. Occupying the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street level, offering an ideal balance of street-level accessibility and user privacy.

 

The entire ground floor has undergone a complete, high-end renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas that requires zero structural work for open-plan tenants, while remaining highly adaptable for clinical division.

 

Versatile Layout Potential: Immediate Turnkey Open Concept or Seamless Medical Build-Out

 

For practices requiring a traditional multi-room clinical environment, the generous footprint easily configures into a highly efficient, multi-operatory floor plan. The space can seamlessly accommodate:

- A spacious, welcoming patient reception and check-in lobby directly off the entryway foyer.

- A dedicated administrative and billing hub with an integrated communication window.

- Multiple private examination rooms or clinical operatories.

- A separate, expansive doctor’s executive consultation suite.

- A staff kitchen/break area and localized storage hubs.

 

The property's flexible layout and Group 3 zoning make it ideal for a wide variety of professional organizations, including:

 

Medical & Clinical Practices: Perfect for private medical practices, dental clinics, dermatology, and multi-provider medical groups.

Outpatient & Wellness Centers: Exceptionally well-suited for sports physical therapy, chiropractic care, acupuncture collectives, and holistic health centers that benefit from the open-concept layout.

Private Consultation & Mental Health Suites: Ideal for psychiatrists, psychologists, speech therapists, and counselors seeking a highly private, quiet, and discreet environment with a dedicated street entrance.

Creative & Cultural Non-Profit Foundations: The pristine open layout is a flawless match for 501(c)(3) non-commercial art galleries, foundations, literary societies, historical archives, or boutique reading rooms.

Educational & Philanthropic Institutions: Highly adaptable for boutique specialized schools, STEM learning labs, private tutoring networks, or administrative headquarters for philanthropic organizations.

 

Located in one of Manhattan’s most pedestrian-friendly and affluent residential enclaves, your space is surrounded by premium retail, fine dining, and neighborhood amenities. Transit options are exceptionally convenient for both staff and clients, with immediate access to Third and Lexington Avenue subway lines (Q and 6 trains) and cross-town bus routes.

Rental Details

  • Number of spaces 1
  • Total square feet available 900 SF
  • For Lease $5,500.00/MO
  • Space Type Medical Office
  • Lease Type Modified Gross
  • Latest Update Jul 13, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
Prime Garden Level Medical/Professional Suite Medical Office $5,500.00/MO 900 SF ground floor Modified Gross

Prime Garden Level Medical/Professional Suite

Space Type

Medical Office

Lease Rate

$5,500.00/MO

Additional Rent

Price on request

Total Space Available

900 SF

Attachments

View Attachments

Additional Space Types

Creative, Office Condo, Institutional/Governmental

Floor

ground floor

Divisible Space

900 - 900 SF

Available Date

Immediate

Lease Type

Modified Gross

Lease Term

From 1 To 10 Years

Renewal Option

Yes

Sublease

No

Build Type

Partial build out

208 E 75th St
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208 E 75th St
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208 E 75th St

Positioned in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners and wellness professionals. Situated on the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street scale, offering an ideal balance of street-level accessibility and patient privacy. 

The entire ground floor has undergone a complete renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas for standard professional offices, physical therapy practices, or holistic health centers. 

The space can seamlessly accommodate:

  • A spacious, welcoming patient reception and check-in lobby directly off the foyer.
  • A dedicated administrative and billing hub
  • Multiple private examination rooms or clinical operatories.
  • A separate, expansive doctor’s executive consultation suite.
  • A large staff kitchen area and localized storage hubs.

Amenities
  • Private street entrance steps off Third Avenue
  • 2026 Renovation
  • Brand new hard wood floors
  • Two working fireplaces
  • Brand new bathroom
  • Shared outdoor garden access

Prime Garden Level Medical/Professional Suite

Space Type
Medical Office
Lease Rate
$5,500.00/MO
Total Space
900 SF
Floor
ground floor
Lease Type
Modified Gross
Space Type

Medical Office

Lease Rate

$5,500.00/MO

Additional Rent

Price on request

Total Space Available

900 SF

Attachments

View Attachments

Additional Space Types

Creative, Office Condo, Institutional/Governmental

Floor

ground floor

Divisible Space

900 - 900 SF

Available Date

Immediate

Lease Type

Modified Gross

Lease Term

From 1 To 10 Years

Renewal Option

Yes

Sublease

No

Build Type

Partial build out

208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
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208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St
208 E 75th St

Positioned in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners and wellness professionals. Situated on the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street scale, offering an ideal balance of street-level accessibility and patient privacy. 

The entire ground floor has undergone a complete renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas for standard professional offices, physical therapy practices, or holistic health centers. 

The space can seamlessly accommodate:

  • A spacious, welcoming patient reception and check-in lobby directly off the foyer.
  • A dedicated administrative and billing hub
  • Multiple private examination rooms or clinical operatories.
  • A separate, expansive doctor’s executive consultation suite.
  • A large staff kitchen area and localized storage hubs.

Amenities
  • Private street entrance steps off Third Avenue
  • 2026 Renovation
  • Brand new hard wood floors
  • Two working fireplaces
  • Brand new bathroom
  • Shared outdoor garden access

Contacts

broker
Alexandru Galiceanu

Lexington Real Estate Group

Principal Broker

Building Details

  • For Lease $5,500.00/MO
  • Property Type Multi-Family
  • Property Size 5,300 SF
  • Units 4
  • Lot Size 0.05 Acre
  • Zoning R8B
  • Additional Rent Price on request
  • # of Floors 5
  • Average Floor Size 950 SF
  • Property Tenancy Single Tenant
  • Building Class B
  • Year Built 1910
  • Year Renovated 2026
  • Date Updated Jul 13, 2026

Location

  • City New York, NY
  • Neighborhood Lenox Hill
  • Zip Code 10021
  • Market Manhattan
  • Map
  • Street
  • Walk score 99/100 Walker's Paradise
  • Transit score 100/100 Rider's Paradise
  • Bike score 83/100 Very Bikeable
Powered by Walk Score ®

Points of Interest

72nd Street & 2nd Avenue at Northwest Corner

0.16 miles

East 77th Street & Lexington Avenue at Southeast Corner

0.17 miles

East 77th Street & Lexington Avenue at Northeast Corner

0.17 miles

77th Street

0.18 miles

East 77th Street & Lexington Avenue at Southwest Corner

0.18 miles

East 77th Street & Lexington Avenue at Northwest Corner

0.19 miles

72nd Street & 2nd Avenue at Southeast Corner

0.19 miles

East 68th Street & Lexington Avenue at Northeast Corner

0.36 miles

East 68th Street & Lexington Avenue at Northwest Corner

0.36 miles

68th Street–Hunter College

0.37 miles

ChargePoint

0.27 miles

plugNYC

0.82 miles

Shell

1.08 miles

BP

1.38 miles

Citgo

1.38 miles

Atlantic

1.43 miles

Mobil

1.48 miles

Sunoco

1.52 miles

iClean

0.12 miles

Surrey Garage

0.36 miles

Metropolitan Museum

0.53 miles

Loeb Boathouse Parking Lot

0.58 miles

Quik Park

0.67 miles

Motorgate Public Parking Garage

0.78 miles

Knickerbocker Plaza Car Park

0.87 miles

Astor Terrace Parking Garage

0.96 miles

Central Parking

1.11 miles

Alpha Garage

1.12 miles

Hertz

0.16 miles

Thrifty

0.43 miles

Budget

0.63 miles

Enterprise CarShare

1.04 miles

Avis

1.26 miles

Queensboro Car Wash

1.38 miles

Cheap Car Lease NYC

1.61 miles

Mizuma International Inc.

1.81 miles

Zipcar

2.20 miles

Hand Car Wash Detailing

3.20 miles

Mezzaluna

0.03 miles

Sashimi Express II

0.04 miles

Juice Press

0.06 miles

B. Cafe

0.06 miles

Tangs

0.07 miles

EJ's Luncheonette

0.08 miles

Seamore's

0.08 miles

Tabata Ramen & Yakitori Bar

0.09 miles

Dunkin'

0.09 miles

THEP

0.09 miles

Nordstrom

0.08 miles

Gristedes

0.11 miles

Morton Williams

0.13 miles

D'Agostino

0.15 miles

Daona Market Place

0.25 miles

Target

0.26 miles

A Matter of Health

0.26 miles

Whole Foods Market

0.32 miles

Agatha & Valentina

0.32 miles

Ouri's Market

0.36 miles

FDNY Engine 44

0.04 miles

New Drug Loft

0.13 miles

Value Price Pharmacy

0.13 miles

Duane Reade

0.16 miles

CVS Pharmacy

0.17 miles

VRMED

0.17 miles

Lenox Hill Hospital

0.20 miles

ThrIVewell Infusion

0.24 miles

Walgreens

0.26 miles

CityMD

0.26 miles

Listing Summary

  • What is the asking price at 208 E 75th St?

    The asking price for spaces at 208 E 75th St rests at $5,500.00/MO.

  • How many office spaces for rent are listed at 208 E 75th St?

    1 office space is listed at 208 E 75th St.

  • What is the total size of 208 E 75th St?

    208 E 75th St has a total of 5,300 square feet.

  • What is the year built for 208 E 75th St?

    The year built for 208 E 75th St is 1910.

Contact Alexandru Galiceanu
broker
Alexandru Galiceanu

Lexington Real Estate Group

Principal Broker

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