Map of Property

For Lease

278 E Main St

278 E Main St, Smithtown, NY 11787

4,400

SF Available

Rental Details

  • Number of spaces 4
  • Total square feet available 4,400 SF
  • For Lease $30.00/SF/YR
  • Space Types Medical Office
  • Date Updated Mar 31, 2026
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Reach out to the broker for more info on lease terms and amenities

For Lease 4 Spaces Available

Contacts

Vincent Piazza

R&R Commercial Realty Group

Building Details

  • For Lease $30.00/SF/YR
  • Property Type Office - Medical Office
  • Property Size 12,000 SF
  • Lot Size 0.74 Acre
  • Building Class C
  • Date Updated Mar 31, 2026

Getting Around

  • Walk Score ®

    Somewhat Walkable (53)

  • Bike Score ®

    Bikeable (50)
Powered by Walk Score ®

Location

  • City Smithtown, NY
  • Neighborhood Village of the Branch
  • Zip Code 11787
  • Market Long Island

Points of Interest

Smithtown

1.04 miles

Platform B

1.05 miles

Platform A

1.05 miles

St. James

2.24 miles

Saint James

2.25 miles

Suffolk / Lowell

4.38 miles

LIRR Station Parking

4.40 miles

Central Islip

4.41 miles

Central lslip Station Entrance

4.42 miles

Speedway

1.86 miles

Mobil

1.94 miles

bp

2.41 miles

Cumberland Farms

2.85 miles

Conoco

3.10 miles

Tesla Supercharger

3.46 miles

QuickChek

3.77 miles

ChargePoint

4.72 miles

South Parking Lot

3.36 miles

David Weld Sanctuary Parking Lot

3.81 miles

Long Island Expressway Exit 56 Park & Ride

3.91 miles

South P Lot

4.00 miles

Parking Lot - Dirt & Gravel Surface

4.74 miles

H Lot

4.92 miles

Hospital Parking Garage

4.93 miles

Staff Parking Lot A

4.96 miles

SAC Lot

5.00 miles

BP

6.93 miles

Setauket Car Wash

6.95 miles

Holbrook Car Wash

7.66 miles

Personal Touch Car Wash of Elwood

7.96 miles

Enterprise

8.48 miles

Detail Center

9.88 miles

Hotoke Japanese Steak House

0.39 miles

Nick's Pizza and Clam Bar

0.57 miles

Smithtown Bagel

0.61 miles

Mannino's

0.69 miles

The Green Turtle

0.70 miles

Watermill Caterers

0.73 miles

Carrabba's Italian Grill

0.73 miles

Raan Thai

1.00 miles

Taco Bell

1.07 miles

Stop & Shop

1.42 miles

Giunta's Meat Farms

1.45 miles

Hauppauge Shopping Centre

2.22 miles

ShopRite

2.31 miles

St. James General Store

2.45 miles

Smith Haven Mall

2.51 miles

ALDI

2.54 miles

Bob's Discount Furniture

2.62 miles

Macy's

2.78 miles

Walgreens

0.65 miles

Personal Women's Care

0.77 miles

Smithtown Fire Department

0.83 miles

Smithtown Fire Department Station 2

1.32 miles

Nesconset Fire Department

1.40 miles

St James Fire Department Station 2

1.73 miles

Nesconset Fire Department Station 2

1.87 miles

CityMD

1.89 miles

CVS Pharmacy

2.19 miles

278 E Main St Listing Summary

  • Office Space Available at 278 E Main St

    Office space currently available at 278 E Main St adds up to a total of 4,400 square feet across 4 listing(s). The largest individual space listed offers 1,200 square feet. Property use types available for lease at this property include: medical office.

  • Learn More about 278 E Main St

    278 E Main St is located in the Long Island market and pertains to the 11787 zip code. The property incorporates a total of 4,400 square feet of space. Within the same building, there are 3,600 square feet of space.

    Interested in researching more about this property? Access in-depth research on 278 E Main St, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

Contact Listing Broker
Vincent Piazza

R&R Commercial Realty Group

  1. 1Main information
  2. 2Extra information
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