For Lease

West Toledo Multi-Use

4221 W Alexis Rd, Toledo, OH 43613

7,200

SF Available
Situated equidistant between Talmadge Rd/I-475 interchange and W Alexis Rd/US 23 interchange.Discover the West Toledo Multi-Use value add opportunity. Located at 4221 W Alexis Rd, Toledo, OH 43613—a 7,200 SF free-standing office building for lease or sale. This Class C property, renovated in 2019, offers a partially renovated shell space ready for your customization, split into two 3,600 SF floors. Prominently fronting 222 ft of Alexis Rd, a 4-lane thoroughfare, it features ample parking with access from Malden Ave and Comet Ave. Equidistant between Talmadge Rd/I-475 and W Alexis Rd/US 23, it’s zoned Regional Commercial for flexible use—offices, medical, or retail. Vacant on a 0.538-acre lot, it’s a value-add opportunity. Contact Patrick West, SVN, with 16+ years managing 1M+ SF, 734-344-2317, or for a tour!a 7,200 SF available for lease.​ This Class C property, refreshed in 2019, offers a blank canvas for your business dreams, split into two 3,600 SF condominiums.​ Boasting 222 ft of frontage on Alexis Rd, a bustling 4-lane thoroughfare, it provides excellent visibility and ample parking with access from Malden Ave and Comet Ave.​ Opportunities for fascia and monument signage elevate your brand.​ Zoned Regional Commercial, it supports retail, medical, or mixed-use ventures.​ Located equidistant between Talmadge Rd/I-475 and W Alexis Rd/US 23, this 0.538-acre lot is ready for immediate occupancy and customization.​

Key features

  • 222 ft frontage on Alexis Rd, a high-traffic 4-lane thoroughfare
  • 7,200 SF shell space, customizable for any tenant
  • Ample parking with 50+ spaces, accessed via Malden and Comet
  • Opportunities for fascia and monument signage to enhance branding
  • Prime West Toledo location between Talmadge/I-475 and US 23
  • Ready for immediate lease with value-add buildout potential
  • Regional Commercial zoning supports retail, medical, or mixed use

Rental Details

  • Number of spaces 2
  • Total square feet available 7,200 SF
  • For Lease $7.50/SF/YR
  • Space Types Medical Office, Showroom - Industrial
  • Lease Type NNN
  • Date Updated May 11, 2026
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Reach out to the broker for more info on lease terms and amenities

For Lease 2 Spaces Available

Contacts

Patrick West

SVN | Ascension Commercial Realty

Building Details

  • For Lease $7.50/SF/YR
  • Property Type Office - General Office
  • Property Size 7,200 SF
  • Units 2
  • Lot Size 0.54 Acre
  • Parking Spaces Avail. 27
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1972
  • Year Renovated 2019
  • Date Updated May 11, 2026

Attachments

Getting Around

  • Walk Score ®

    Car-Dependent (42)

  • Bike Score ®

    Somewhat Bikeable (35)
Powered by Walk Score ®

Location

  • City Toledo, OH
  • Neighborhood Franklin Park
  • Zip Code 43613
  • Market Toledo

Points of Interest

Marathon

1.96 miles

Shell

2.23 miles

Kroger

2.32 miles

BP

2.46 miles

Kroger Fuel Station

2.61 miles

Tesla Supercharger

9.85 miles

Dave White Chevrolet Car Lot

2.05 miles

Wildwood Parking Lot #8

2.91 miles

Wildwood Parking

2.92 miles

Wildwood Parking Lot #5

2.98 miles

Wildwood Parking Lot #4

3.00 miles

Wildwood Parking Lot #6

3.00 miles

Wildwood Parking Lot #3

3.02 miles

St. Joe's Park and Ride Lot

3.03 miles

Russ' Auto Car Wash Inc.

3.09 miles

Jackman Laskey Car Wash

3.24 miles

Expresso Car Wash

3.33 miles

Enterprise

3.55 miles

Avis;Toledo Phone Repair

3.99 miles

BK Car Wash

5.66 miles

Central Car Wash

6.74 miles

Super Wash

7.54 miles

Marathon Car Wash

7.57 miles

Sakura Japanese Steakhouse

1.29 miles

Dairy Queen

1.29 miles

Firehouse Subs

1.31 miles

A Mango Restaurant

1.31 miles

Grape Leaf Express

1.31 miles

Marco's Pizza

1.31 miles

Sori Sushi

1.31 miles

Outback Steakhouse

1.31 miles

CoreLife Eatery

1.36 miles

Monroe Street Plaza

1.32 miles

Marshalls

1.38 miles

ALDI

1.53 miles

Target

1.54 miles

Dillard's

1.67 miles

Macy's

1.74 miles

JCPenney

1.76 miles

Franklin Park Mall

1.79 miles

Kohl's

1.85 miles

Walgreens

1.01 miles

Passport Health Toledo Travel Clinic

1.04 miles

Regency Hospital

1.27 miles

ProMedica Health and Wellness Center

1.78 miles

ProMedica Health Center

2.10 miles

Mercy Health — St. Anne Hospital

2.12 miles

Woodley Medical

2.16 miles

Woodley Medical Arts

2.18 miles

Flower Hospital

2.52 miles

4221 W Alexis Rd Listing Summary

  • Office Space Available at 4221 W Alexis Rd

    Office space currently available at 4221 W Alexis Rd adds up to a total of 7,200 square feet across 2 listing(s). The largest individual space listed offers 3,600 square feet. Property use types available for lease at this property include: medical office and showroom - industrial.

  • Learn More about 4221 W Alexis Rd

    4221 W Alexis Rd is located in the Toledo market and pertains to the 43613 zip code. The property incorporates a total of 7,200 square feet of space. 4221 W Alexis Rd was built in 1972. The most recent renovation work at this property was completed in 2019.

    Interested in researching more about this property? Access in-depth research on 4221 W Alexis Rd, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Franklin Park neighborhood, where 4221 W Alexis Rd is located, you can currently find 8 office space(s) for rent. In total, this amounts to 26,850 square feet of available office space for lease opportunities.

Contact Listing Broker
Patrick West

SVN | Ascension Commercial Realty

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