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For Lease

McKinney Medical Building - Class A Medical Office Building Adjacent to Expanding Medical City McKinney Campus

4601 Medical Center Dr, McKinney, TX 75069

18,055

SF Available
McKinney Medical Building is a 33,592-square-foot Class A medical outpatient facility strategically positioned directly across from the 311-bed Medical City McKinney campus—one of Collin County’s largest and most advanced healthcare destinations. Originally built in 2006 and renovated in 2018, the property features a modern, healthcare-focused design with two linear accelerator vaults, controlled 24-hour access, a covered patient drop-off and pick-up area, and a strong 5.0-per-1,000 SF parking ratio. The fee-simple property offers excellent visibility and accessibility near the intersection of U.S. Highway 75 and Sam Rayburn Tollway, serving the rapidly growing Allen/McKinney medical submarket. Surrounded by significant hospital expansion—including a new women’s hospital, recently delivered and planned medical office buildings, and ongoing inpatient tower development—McKinney Medical Building is well positioned to serve physicians, outpatient providers, and healthcare investors seeking space within one of North Texas’ most sought-after healthcare corridors.

Key features

  • Campus-adjacent location directly across from Medical City McKinney, a 311-bed acute care hospital and leading North Texas healthcare campus
  • Class A Medical Office Building for Sale or Lease totaling 33,592 SF in McKinney, Texas
  • Dallas–Fort Worth MSA location, one of the largest and strongest metropolitan economies in the United States
  • Fee-simple ownership with no use restrictions, offering long-term flexibility for investors and owner-users
  • Healthcare-focused design featuring two linear accelerator (LINAC) vaults, controlled 24-hour access, and covered patient drop-off/pick-up
  • Ideal for healthcare investors, physician groups, or owner-users seeking proximity to a major hospital and long-term demand drivers
  • Located in the Allen/McKinney medical submarket, one of the fastest-growing healthcare corridors in North Texas
  • Modern building constructed in 2006 and renovated in 2018, minimizing near-term capital expenditures
  • Multiple suite sizes available, accommodating a range of medical specialties and outpatient users
  • Positioned within a rapidly expanding hospital ecosystem, including a new $50M five-story MOB (2025), $17M women’s hospital, and ongoing $142M inpatient tower expansion
  • Serves an affluent and rapidly growing population, with exceptional population and 65+ demographic growth supporting sustained medical demand
  • Strategic visibility and access near U.S. Highway 75 (157,000+ AADT) and Sam Rayburn Tollway (34,000+ AADT)
  • Strong parking ratio of approximately 5.0 per 1,000 SF, providing convenience for patients, staff, and providers

Rental Details

  • Number of spaces 1
  • Total square feet available 18,055 SF
  • For Lease Contact for pricing
  • Space Types Unassigned
  • Date Updated May 28, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

Space Available

  • Space Type Unassigned
  • Lease Rate Contact for pricing
  • Total Space Available 18,055 SF
  • Attachments pdf opens in new window
  • Divisible Space 1,683 - 18,055 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No
  • Build Type Full build out
broker
Tanya Hart
broker
Allison Frizzo
broker
Lauren Jahner

Contacts

broker
Tanya Hart
broker
Allison Frizzo
broker
Lauren Jahner

Building Details

  • For Lease Contact for pricing
  • Property Type Other
  • Year Built 2006
  • Year Renovated 2018
  • Date Updated May 28, 2026

Getting Around

  • Walk Score ®

    Car-Dependent (17)
  • Bike Score ®

    Somewhat Bikeable (31)
Powered by Walk Score ®

Location

  • City McKinney, TX
  • Neighborhood Villages of McKinney
  • Zip Code 75069

Points of Interest

Valero

0.86 miles

QuikTrip

1.62 miles

RaceTrac

1.70 miles

Shell

1.72 miles

Tom Thumb

1.80 miles

ChargePoint

2.36 miles

Tesla Supercharger

3.08 miles

Lot C - Visitor

1.39 miles

Lot R - Band, Drill Team and Cheer Parking

1.47 miles

Lot S - CEC/Staff Parking

1.52 miles

Lot E - Home

1.58 miles

Lot H - Home

1.59 miles

Lot P - Home

1.60 miles

South Garage

2.56 miles

LOT 4

2.76 miles

LOT F

2.81 miles

Super B Carwash

3.32 miles

Zips Car Wash

3.76 miles

QuikWash America

4.01 miles

The Car Wash Zone

4.02 miles

7-Eleven

4.72 miles

City Speed Car Wash

5.60 miles

Carnation Auto Spa

6.42 miles

Xtreme Car Wash

9.07 miles

White Water Express Car Wash

9.15 miles

Razzoo's Cajun Cafe

0.78 miles

Subway

0.78 miles

Texas Roadhouse

0.79 miles

Wendy's

0.85 miles

Panera Bread

0.91 miles

Chipotle

1.01 miles

Saltgrass Steak House

1.06 miles

Thai Noodle Wave

1.06 miles

Rockfish Seafood Grill

1.10 miles

Albertsons

0.79 miles

Trader Joe's

1.11 miles

Tom Thumb

1.74 miles

Macy's

2.17 miles

Dillard's

2.22 miles

ALDI

2.26 miles

Whole Foods Market

2.34 miles

Ross

2.70 miles

TJ Maxx

2.73 miles

Fairview Fire Station No. 1

1.51 miles

Tom Thumb Pharmacy

1.75 miles

Walgreens

1.86 miles

Legacy ER & Urgent Care

1.91 miles

CVS Pharmacy

2.16 miles

elevation chiropractic

2.18 miles

McKinney Fire Station 3

2.35 miles

McKinney Fire Station 4

2.58 miles

Walmart Pharmacy

2.75 miles

4601 Medical Center Dr Listing Summary

  • What is the year built for McKinney Medical Building - Class A Medical Office Building Adjacent to Expanding Medical City McKinney Campus?

    The year built for McKinney Medical Building - Class A Medical Office Building Adjacent to Expanding Medical City McKinney Campus is 2006.

Contact McKinney Medical Building - Class A Medical Office Building Adjacent to Expanding Medical City McKinney Campus
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