US Hwy 281 & Encino Rio
19818 US-281, San Antonio, TX 78258
44,859
SF Available±9.32 Acres (Divisible) | Hwy 281 & Encino Rio
- Highly visible location
- Development ready
- Impervious Cover - Category 2
- Excellent ingress & egress
- 5-mile trade area has experienced a strong annual growth over the last 5 years and is projected to continue growing.
Rental Details
- Number of spaces 1
- Total square feet available 44,859 SF
- For Lease $39.00/SF/YR
- Space Types Medical Office
- Lease Type NNN
- Date Updated May 14, 2026
Reach out to the broker for more info on lease terms and amenities
True
For Lease 1 Space Available
Space Available |
David Held
Endura Advisory Group |
Contacts
Endura Advisory Group
Building Details
- For Lease $39.00/SF/YR
- Property Type Office - Medical Office
- Property Size 44,859 SF
- Lot Size 9.32 Acre
- Date Updated May 14, 2026
Getting Around
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Walk Score ®
Car-Dependent (12) -
Transit Score ®
Minimal Transit (20) -
Bike Score ®
Somewhat Bikeable (27)
Location
- City San Antonio, TX
- Neighborhood Encino Park
- Zip Code 78258
- Market San Antonio
Points of Interest
Wonderland Express Train Station
7.29 miles
Spassburg Train Station
9.27 miles
Crackaxle Train Station
9.47 miles
Valero
2.37 miles
H-E-B Fuel
3.26 miles
Shell
3.88 miles
Ten-o-Five Market
4.26 miles
Tesla Supercharger
9.09 miles
Sky Plaza Parking
6.22 miles
Big Brother and Big Sister Parking
6.24 miles
Employee parking
6.63 miles
Short Term Parking & Car Rental
7.01 miles
Oversized Vehicle Parking
7.05 miles
Long Term Parking
7.07 miles
Orange Lot
7.27 miles
Green Lot
7.28 miles
Rideshare Waiting Lot
7.39 miles
Champions Car Wash
1.75 miles
Swiftwater Car Wash
2.25 miles
Circle K
2.35 miles
Avis
2.45 miles
Budget
2.45 miles
Pirates Cove Car Wash
2.87 miles
Enterprise
3.12 miles
H-E-B Car Wash
3.26 miles
Hertz
4.86 miles
McDonald's
0.63 miles
Whataburger
0.74 miles
Arby's
0.75 miles
Chick-fil-A
0.83 miles
Schlotzsky's
0.84 miles
Jack in the Box
0.89 miles
Taco Bell
1.00 miles
Popeyes
1.03 miles
Panda Express
1.07 miles
Walmart Supercenter
1.20 miles
Burlington
1.21 miles
H-E-B
1.44 miles
Marshalls
1.45 miles
Target
2.05 miles
Sprouts Farmers Market
2.33 miles
Big Lots
2.34 miles
Trader Joe's
2.68 miles
Buff City Soap
3.25 miles
HealthTexas - Stone Oak
0.84 miles
H-E-B Pharmacy
1.03 miles
Methodist Stone Oak Hospital
1.23 miles
San Antonio Fire Station 46
1.33 miles
Costco Pharmacy
1.40 miles
South Texas Spine and Surgical Hospital
1.43 miles
North Central Federal Clinic
1.60 miles
Walgreens
1.65 miles
CVS Pharmacy
1.75 miles
19818 US-281 Listing Summary
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Office Space Available at 19818 US-281
Office space currently available at 19818 US-281 adds up to a total of 44,859 square feet across 1 listing(s). The largest individual space listed offers 44,859 square feet. Property use types available for lease at this property include: medical office.
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Learn More about 19818 US-281
19818 US-281 is located in the San Antonio market and pertains to the 78258 zip code. The property incorporates a total of 44,859 square feet of space.
Interested in researching more about this property? Access in-depth research on 19818 US-281, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.
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Get to Know the Neighborhood
In the Encino Park neighborhood, where 19818 US-281 is located, you can currently find 27 office space(s) for rent. In total, this amounts to 127,602 square feet of available office space for lease opportunities.
Endura Advisory Group
