5406 US-280
5406 US-280, Birmingham, AL 35242
Join Andrews Sports Medicine, Skin Wellness Dermatology, ENT for Kids, and Birmingham Orthodontics, in this premier medical location on Highway 280.
The Crossroads at Greystone offers a convenient, neighborhood center setting for your next location. Building signage and ample parking in a drive-up setting provides an easy experience for patients and visitors.
Multiple suite sizes are available and build out packages can be customized to your exact layout needs.
85,500 vehicles per day on Highway 280
18,800 vehicles per day on Highway 119 (Cahaba Valley Road)
Excellent signage (building and monument)
Drive up parking for a convenient patient experience
Multiple ingress/egress points and traffic light access to Highway 280
Convenient to Birmingham’s major neighborhoods: Inverness, Meadowbrook, Greystone and continued growth down Highway 280
Rental Details
- Number of spaces 5
- Total square feet available 13,345 SF
- For Lease $24.00/SF/YR
- Space Type Retail
- Latest Update Oct 12, 2026
Reach out to the broker for more info on lease terms and amenities
True
5 Spaces Available
| Space Name | Space Type | Lease Rate | Total Space | Floor | Lease Type | |
|---|---|---|---|---|---|---|
| #B101 | Retail | $24.00/SF/YR | 3,600 SF | - | - | |
| #B105 | Retail | $24.00/SF/YR | 1,200 SF | - | - | |
| #D 101 | Retail | $24.00/SF/YR | 6,145 SF | - | - | |
| #D112 | Retail | $24.00/SF/YR | 1,200 SF | - | - | |
| #D113 | Retail | $24.00/SF/YR | 1,200 SF | - | - |
#B101
- Space Type
- Retail
- Lease Rate
- $24.00/SF/YR
- Total Space
- 3,600 SF
#B105
- Space Type
- Retail
- Lease Rate
- $24.00/SF/YR
- Total Space
- 1,200 SF
#D 101
- Space Type
- Retail
- Lease Rate
- $24.00/SF/YR
- Total Space
- 6,145 SF
#D112
- Space Type
- Retail
- Lease Rate
- $24.00/SF/YR
- Total Space
- 1,200 SF
#D113
- Space Type
- Retail
- Lease Rate
- $24.00/SF/YR
- Total Space
- 1,200 SF
Contacts
Lincoln Holdings
Building Details
- For Lease $24.00/SF/YR
- Property Type Retail
- Property Size 13,345 SF
- Additional Rent Price on request
- Date Updated Oct 12, 2026
Location
- City Birmingham, AL
- Neighborhood Greystone
- Zip Code 35242
- Market Birmingham
-
Walk score 54/100 Somewhat Walkable -
Bike score 39/100 Somewhat Bikeable
Points of Interest
Shell
0.08 miles
Cowboys
0.74 miles
BP
1.61 miles
Chevron
1.77 miles
1314- Dunnavant Valley Chevron
2.43 miles
Tesla Supercharger
2.48 miles
ChargePoint
7.39 miles
Mountain Brook, AL Supercharger
7.58 miles
Leeds, AL Supercharger
9.99 miles
Grandview Emergency Parking
2.83 miles
Grandview Parking Deck
2.94 miles
Parking Deck
3.23 miles
North Trailhead Parking
4.55 miles
School bus parking lot
7.03 miles
Pizitz Parking lot
7.13 miles
Track and Soccer Stadium Parking
7.68 miles
Publix
0.28 miles
Walmart Supercenter
0.41 miles
Sprouts Farmers Market
0.73 miles
TJ Maxx
1.26 miles
Winn-Dixie
1.35 miles
Kohl's
1.47 miles
The Fresh Market
1.69 miles
ALDI
1.93 miles
Piggly Wiggly
2.39 miles
Target
2.47 miles
Listing Summary
-
Retail Space Costs at 5406 US-280
The asking rent for retail space in this property starts at $24.00/SF/YR.
-
Retail Space Available The property exclusively contains Retail space totaling 13,345 square feet.
-
Space Sizes - The property houses 5 retail spaces in the 1,000 to 10,000 square feet range, which can serve small or medium-sized retail businesses with growth potential.
-
Area Characteristics 5406 US-280 is located in the Greystone neighborhood of Birmingham. The Greystone retail market offers 14 retail listings, representing a total of 30,719 square feet of retail space for lease.
The most common retail type in the Greystone neighborhood is Five Points South, of which the market currently offers 22 spaces.
You can also find 14 Greystone spaces. Additionally, leasing opportunities here include 13 Roebuck spaces.
Lincoln Holdings
