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For Lease

Britannia Oyster Point II - Building B

331 Oyster Point Blvd, South San Francisco, CA 94080

93,333

SF Available

Rental Details

  • Number of spaces 3
  • Total square feet available 93,333 SF
  • For Lease Contact for pricing
  • Space Types Life Sciences
  • Date Updated May 22, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

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For Lease 3 Spaces Available

331 Oyster Point Boulevard 1st Floor

  • Space Type Life Sciences
  • Lease Rate Contact for pricing
  • Total Space Available 30,000 SF
  • Floor 1
  • Max Contiguous 60,000 SF
  • Available Date Immediate
  • Renewal Option No
  • Sublease Yes
broker
Mary Hines

CBRE

broker
Jennifer Vergara

CBRE

331 Oyster Point Boulevard 2nd Floor

  • Space Type Life Sciences
  • Lease Rate Contact for pricing
  • Total Space Available 33,333 SF
  • Floor 2
  • Divisible Space 33,333 - 33,333 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No
  • Build Type Shell

Life science warm shell ready for tenant improvements 

broker
Richard Friday

CBRE

broker
Christopher R. Jacobs

CBRE

331 Oyster Point Boulevard 3rd Floor

  • Space Type Life Sciences
  • Lease Rate Contact for pricing
  • Total Space Available 30,000 SF
  • Floor 2
  • Max Contiguous 60,000 SF
  • Available Date Immediate
  • Renewal Option No
  • Sublease Yes

2 7 Private Offices 1 1 Conference Rooms 9 0 Cubes 

broker
Mary Hines

CBRE

broker
Jennifer Vergara

CBRE

Contacts

broker
Jennifer Vergara

CBRE

broker
Mary Hines

CBRE

broker
Richard Friday

CBRE

broker
Christopher R. Jacobs

CBRE

Building Details

  • For Lease Contact for pricing
  • Property Type Office - Life Sciences
  • Property Size 128,751 SF
  • Lot Size 8.84 Acre
  • Parking Spaces Avail. 360
  • Parking Ratio 2.80 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 2008
  • Date Updated May 22, 2026

Getting Around

  • Walk Score ®

    Car-Dependent (39)
  • Bike Score ®

    Bikeable (64)
Powered by Walk Score ®

Location

  • City South San Francisco, CA
  • Neighborhood Oyster Point
  • Zip Code 94080
  • Market San Francisco
  • Map
  • Street

Points of Interest

San Bruno

2.29 miles

West Field Road

2.93 miles

South San Francisco

2.96 miles

Taxi Stand at SFO, Domestic Terminal 3 (Arrivals Level in front of Door 5, 6, 7, 8, 9, 10)

3.15 miles

Terminal 3

3.18 miles

Taxi Stand at SFO, Domestic Terminal 2 (Arrivals Level in front of Door 1, 2, 3, 4)

3.23 miles

San Francisco International Airport (SFO)

3.24 miles

San Francisco International Airport

3.26 miles

Sunnydale

3.28 miles

Fathom Marine

0.64 miles

Shell

0.82 miles

Golden Gate Gasoline

0.88 miles

Speedway

1.03 miles

76

1.18 miles

Chico's

1.20 miles

True Zero

1.38 miles

Valero

1.48 miles

EV Range

1.54 miles

United Airlines East Parking Lot

1.80 miles

SFO Long-Term Parking Garage #1

1.94 miles

SFO Long-Term Parking Garage #2

2.03 miles

Cell Phone Waiting Lot

2.09 miles

SFO TNC Staging Lot 3

2.14 miles

SFO Long-Term Parking

2.15 miles

Charter Bus Staging Lot

2.15 miles

Worksite Labs Testing Site at SFO

2.17 miles

Taxi Staging Lot

2.19 miles

Advantage Rent A Car

1.57 miles

Fox Rent a Car

1.61 miles

Hertz

2.46 miles

Enterprise

2.46 miles

Alamo

2.47 miles

Dollar

2.48 miles

Budget

2.48 miles

SIXT Rent a Car San Francisco Int Airport

2.49 miles

Avis

2.50 miles

Wendy's

1.01 miles

El Palenque Taqueria

1.02 miles

Amoura

1.07 miles

Taqueria Celaya

1.10 miles

Pronto's

1.18 miles

Dumpling Empire

1.19 miles

Cafe Bunn Mi

1.20 miles

Flavas Jamaican Grill

1.21 miles

Sky Cafe

1.21 miles

Safeway

2.29 miles

Target

2.36 miles

Lucky

2.37 miles

Marshalls

2.38 miles

The Shops at Tanforan

2.43 miles

JCPenney

2.45 miles

Smart & Final

2.47 miles

Pacific Supermarket

2.56 miles

Besan’s International Market

2.97 miles

Brisbane Fire Department

1.77 miles

Brisbane Police Department

1.77 miles

San Bruno Police Department

2.30 miles

SFO Marine Emergency Response Facility

2.30 miles

SFO Police Training Facility

2.38 miles

Walgreens

2.43 miles

South San Francisco Police Department

2.44 miles

Fire Station 63

2.63 miles

Sunshine Pharmacy

2.68 miles

331 Oyster Point Blvd Listing Summary

  • Office Space Available at 331 Oyster Point Blvd

    Office space currently available at 331 Oyster Point Blvd adds up to a total of 93,333 square feet across 3 listing(s). The largest individual space listed offers 33,333 square feet. Property use types available for lease at this property include: life sciences. Sublease opportunities at 331 Oyster Point Blvd include 2 space(s).

  • Learn More about 331 Oyster Point Blvd

    331 Oyster Point Blvd is located in the San Francisco market and pertains to the 94080 zip code. The property incorporates a total of 93,333 square feet of space. 331 Oyster Point Blvd features a parking ratio of 2.80 / 1,000 SF, offering a total of 360 parking spaces. 331 Oyster Point Blvd was built in 2008.

    Interested in researching more about this property? Access in-depth research on 331 Oyster Point Blvd, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Oyster Point neighborhood, where 331 Oyster Point Blvd is located, you can currently find 38 office space(s) for rent. In total, this amounts to 1,376,070 square feet of available office space for lease opportunities.

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