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For Lease

Southglenn Professional Center

6650 South Vine Street, Centennial, CO 80121

7,476

SF Available

Rental Details

  • Number of spaces 5
  • Total square feet available 7,476 SF
  • For Lease $1,634.00 - $4,422.55/MO
  • Space Types Medical Office, General Office
  • Lease Type Full Service
  • Date Updated Apr 24, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 5 Spaces Available

#200

  • Space Type Medical Office
  • Lease Rate $4,422.55/MO
  • Total Space Available 2,057 SF
  • Divisible Space 2,057 - 2,057 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Fully functional, recently remodeled dental / endodontic office complete with over $300,000 of in-place dental equipment including chairs, plumbing, x-ray equipment, and more. The space features a gracious reception, 3 dental chairs, x-ray room, in-suite bathroom, kitchen and office. Perfect for a new practice! 

The monthly price includes rent, all utilities, access to conference room, and cleaning 5 nights per week.

 

broker
Parker Schroeder

Good Signature Management

#230

  • Space Type General Office
  • Lease Rate $1,634.00/MO
  • Total Space Available 760 SF
  • Divisible Space 760 - 760 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Small office suite with one executive office, a kitchen, a reception, and two smaller rooms. Perfect for a solo practitioner or small startup.

The monthly price includes rent, all utilities, access to conference room, and cleaning 5 nights per week.

broker
Parker Schroeder

Good Signature Management

#250

  • Space Type General Office
  • Lease Rate $2,072.60/MO
  • Total Space Available 964 SF
  • Divisible Space 964 - 964 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

This suite comes with a private restroom, three offices, storage, and a reception. Pictures coming soon.

The monthly price includes rent, all utilities, access to conference room, and cleaning 5 nights per week.

broker
Parker Schroeder

Good Signature Management

#L50

  • Space Type General Office
  • Lease Rate $2,085.60/MO
  • Total Space Available 1,264 SF
  • Divisible Space 1,264 - 1,264 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Discounted to $19.80/RSF/Yr! Lower Level suite with three offices, a large open room / reception, and private patio. Great natural light and private outdoor patio.

The monthly price includes rent, all utilities, access to conference room, and cleaning 5 nights per week.

broker
Parker Schroeder

Good Signature Management

#L80

  • Space Type General Office
  • Lease Rate $4,011.15/MO
  • Total Space Available 2,431 SF
  • Divisible Space 2,431 - 2,431 SF
  • Available Date 30 Days
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Discounted to $19.80/RSF/Yr! This suite features three private rooms, a patio, storage, washer and dryer connections, a reception, and an open area. Multiple sinks and plumbing fixtures make this a perfect space for an esthetician or light medical suite! Available within 30 days!

The monthly price includes rent, all utilities, access to conference room, and cleaning 5 nights per week.

broker
Parker Schroeder

Good Signature Management

Contacts

broker
Parker Schroeder

Good Signature Management

Building Details

  • For Lease $1,634.00 - $4,422.55/MO
  • Property Type Office - General Office
  • Property Size 28,167 SF
  • Lot Size 1.22 Acre
  • Parking Spaces Avail. 95
  • Parking Ratio 3.40 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1975
  • Date Updated Apr 24, 2026

Getting Around

  • Walk Score ®

    Very Walkable (73)
  • Transit Score ®

    Some Transit (26)
  • Bike Score ®

    Bikeable (59)
Powered by Walk Score ®

Location

  • City Centennial, CO
  • Neighborhood Broadway Estates
  • Zip Code 80121
  • Market Denver
  • Map
  • Street

Points of Interest

10th & Osage

9.64 miles

Exxon

1.32 miles

Conoco

1.35 miles

Mobil

1.36 miles

Imart

1.59 miles

Sinclair

1.72 miles

King Soopers

1.76 miles

Circle K

1.91 miles

ChargePoint

3.30 miles

Blink

3.57 miles

C-470 & South University Blvd Park n Ride

2.41 miles

Skate Park & Hockey

2.63 miles

Gravel Parking Lot

2.69 miles

County Line Road Trailhead

2.84 miles

Littleton Downtown Station Park-n-Ride

2.99 miles

S Dahlia St Trailhead

3.16 miles

Toepfer Park

3.41 miles

Littleton - Mineral Park & Ride

3.49 miles

Windermere Car Wash

3.05 miles

Jazz Car Wash

3.17 miles

Metro Express

3.94 miles

Car Wash Express Highlands Ranch

3.96 miles

Car Wash

4.00 miles

Waterway Carwash

4.07 miles

Hertz

4.16 miles

conoco car wash

4.24 miles

Waterway Car Wash

4.31 miles

MICI

0.15 miles

Noodles & Company

0.17 miles

Qdoba

0.18 miles

Bad Daddy Burgers

0.24 miles

Snooze

0.24 miles

Roro Juice

0.28 miles

Pho 95

0.30 miles

Bombay Bites

0.31 miles

Diego Zhang's Burger Cafe

0.32 miles

Ross

0.20 miles

Whole Foods Market

0.30 miles

Natural Grocers

0.30 miles

TJ Maxx

0.87 miles

Trader Joe's

0.96 miles

Dry Creek Center

1.17 miles

King Soopers

1.23 miles

Target

2.14 miles

Sprouts Farmers Market

2.35 miles

Rite Aid

0.31 miles

Cherry Hills Assisted Living & Memory Care

0.42 miles

AFC Urgent Care

0.79 miles

Pharmaca

0.96 miles

South Metro Fire Rescue - Station 15

1.15 miles

South Metro Fire Station 14

1.20 miles

South Metro Fire Rescue Station 37

1.29 miles

South Metro Fire Station 12

1.37 miles

AdventHealth Littleton Hospital

1.84 miles

6650 South Vine Street Listing Summary

  • Office Space Available at 6650 South Vine Street

    Office space currently available at 6650 South Vine Street adds up to a total of 7,476 square feet across 5 listing(s). The largest individual space listed offers 2,431 square feet. Property use types available for lease at this property include: medical office and general office.

  • Learn More about 6650 South Vine Street

    6650 South Vine Street is located in the Denver market and pertains to the 80121 zip code. The property incorporates a total of 7,476 square feet of space. 6650 South Vine Street features a parking ratio of 3.40 / 1,000 SF, offering a total of 95 parking spaces. 6650 South Vine Street was built in 1975.

    Interested in researching more about this property? Access in-depth research on 6650 South Vine Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Broadway Estates neighborhood, where 6650 South Vine Street is located, you can currently find 16 office space(s) for rent. In total, this amounts to 212,199 square feet of available office space for lease opportunities.

Contact Listing Broker
broker
Parker Schroeder

Good Signature Management

  1. 1Main information
  2. 2Extra information
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