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  1. Commercial Properties
  2. FL
  3. Central Pasco
  4. San Antonio

52 & Main

For Sale

12021 Main St, San Antonio, FL 33576

The property is on Main Street in the historic town of San Antonio in east Pasco County, one of the oldest incorporated communities in the county and known for its small town charm and walkable downtown core. Founded in 1882, the town still centers on its Main Street and hosts the well known San Antonio Rattlesnake Festival that draws visitors from across the region each year. It sits just off State Road 52 with direct access to Interstate 75 at Exit 285, tying the town to the greater Tampa Bay region and to the U.S. 301 corridor through neighboring Dade City. Saint Leo University and the Lake Jovita golf community are next door, and East Pasco has become one of the fastest growing parts of one of the fastest growing counties in Florida with new housing pushing east along the SR 52 corridor toward San Antonio. The result is a rare mix of established historic character and real growth momentum in the path of the region's expansion.The property is 1.56 acres in downtown San Antonio zoned C2, the county's general commercial district. It carries roughly 275 feet of frontage on State Road 52 with additional access off both Main Street and Hill Avenue. The C2 zoning supports a broad range of retail office and commercial uses. Given its size frontage and setting in the heart of town the site also lends itself to a community gathering concept such as a weekly farmers and artisan market that could anchor downtown San Antonio and draw steady foot traffic. The highway frontage, dual access and flexible zoning make it a strong infill commercial site with room for a creative vision.

Building Details

  • For Sale Subject To Offer
  • Property Type VacantLand
  • Property Size 1,284 SF
  • Units 1
  • Lot Size 1.56 Acre
  • Additional Rent Price on request
  • Year Built 1940
  • Date Updated Sep 22, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

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Contacts

broker
Josh Streitmatter

Eshenbaugh Land Company

Location

  • City San Antonio, FL
  • Neighborhood San Antonio
  • Zip Code 33576
  • Market Tampa St Petersburg Clearwater
  • Map
  • Street
  • Walk score 46/100 Car-Dependent
  • Bike score 30/100 Somewhat Bikeable
Powered by Walk Score ®

Points of Interest

Shell

0.09 miles

Marathon

0.10 miles

Flying J

3.03 miles

RaceTrac

3.64 miles

Citgo

5.18 miles

Sunoco

6.32 miles

7-Eleven

6.85 miles

Visitor Parking

7.93 miles

Faculty Parking

8.00 miles

Student Parking

8.08 miles

Blue Beacon

2.93 miles

Top Edge Car Wash Wesley Chapel

8.06 miles

Enterprise

8.14 miles

The Palms Car Wash

8.72 miles

Denny's

3.04 miles

Burger King

5.25 miles

McDonald's

5.30 miles

Taco Bell

5.32 miles

Beef 'O' Brady's

5.57 miles

Steph's Southern Soul Restaurant

5.79 miles

Chili's

6.75 miles

Chick-fil-A

6.93 miles

Arby's

6.95 miles

Golden Corral

7.33 miles

Publix

1.41 miles

Winn-Dixie

5.14 miles

Walmart

5.36 miles

Walmart Supercenter

6.63 miles

TJ Maxx

7.71 miles

Ross

7.91 miles

Pasco County Fire Rescue - Station 27

0.23 miles

San Antonio Fire Department Station 27

0.27 miles

Pasco Sheriff's Office - East Operations Center

3.80 miles

Pasco Country Fire Rescue - Station 38

4.54 miles

AdventHealth Dade City

4.60 miles

Florida Medical Clinic

4.68 miles

Pasco County Sheriff's Office Records

4.94 miles

Walgreens

5.22 miles

CVS Pharmacy

5.32 miles

Dade City Police Department

5.70 miles

Listing Summary

  • What is the asking price at 52 & Main?

    The asking price for 52 & Main is currently available on demand. Contact the listing broker for details.

  • What is the total size of 52 & Main?

    52 & Main has a total of 1,284 square feet.

  • What is the year built for 52 & Main?

    The year built for 52 & Main is 1940.

Contact Josh Streitmatter
broker
Josh Streitmatter

Eshenbaugh Land Company

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