Des Moines, IA Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

188 Listings

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$22.00/SF/YR
Gateway East Building
601 East Locust Street, Historic East Village, Des Moines, IA
Space Type
Office
1 space

2,844 SF
1 of 1
$12.00/SF/YR
The Teachout Building
500 E Locust St, Historic East Village, Des Moines, IA
Space Type
Office
3 spaces

1,920 SF
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3 of 3
$11.00/SF/YR
420 Watson Powell Jr. Way
420 Watson Powell Jr. Way, Downtown Des Moines, Des Moines, IA
Space Type
Office
1 space

2,576 SF
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2 of 3

3 of 3
Price on request
Iowa State Education Association Headquarters
777 3rd Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
1 space

30,210 SF
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$6.25/SF/YR
2301 Fleur Drive
2301 Fleur Drive, Grays Lake, Des Moines, IA
Space Type
Industrial
1 space

70,180 SF
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$460,000
303 University Avenue
303 University Avenue, River Bend, Des Moines, IA
Property Type
Office
Built in 1981

3,623 SF
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2 of 2
$431,000
SE 14th Walmart Outlot For Sale
4807 SE 14th Street, Easter Lake Area, Des Moines, IA
Property Type
VacantLand
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2 of 2
$699,000
1401 Ohio St
1401 Ohio St, Capitol Park, Des Moines, IA
Property Type
Industrial
Built in 1960

7,900 SF
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$7.00 - $14.00/SF/YR
1536 E Army Post Rd
1536 E Army Post Rd, Easter Lake Area, Des Moines, IA
Space Type
Office
1 space

14,198 SF
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$1,550,000
520 SW 5th Street
520 SW 5th Street, Downtown Des Moines, Des Moines, IA
Property Type
VacantLand
Built in 1959

10,550 SF
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2 of 2
$1,800,000
Highland Park Historic Retail Investment
3523 6th Ave, Highland Park, Des Moines, IA
Property Type
Retail
7,080 SF
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$675,000
4224 E University Ave
4224 E University Ave, Grays Woods, Des Moines, IA
Property Type
VacantLand
Built in 1965

2,000 SF
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Price on request
Krause Gateway Center
1459 Grand Avenue, Downtown Des Moines, Des Moines, IA
Space Type
Office
2 spaces

25,365 - 36,955 SF
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$7.00/SF/YR
520 SW 5th Street
520 SW 5th Street, Downtown Des Moines, Des Moines, IA
Space Type
Land
1 space

10,550 SF
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3 of 3
$17.00/SF/YR
MercyOne Hosptial - Mercy Medical Plaza
411 Laurel Street, Cheatom Park, Des Moines, IA
Space Type
Office
2 spaces

2,296 - 2,693 SF
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2 of 2
$13.00/SF/YR
Highland Park Historic Retail Investment
3523 6th Ave, Highland Park, Des Moines, IA
Space Type
Retail
1 space

1,405 SF
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$12.50/SF/YR
East Grand Office Park - 200 East Grand Avenue
200 East Grand Avenue, Historic East Village, Des Moines, IA
Space Type
Office
3 spaces

14,280 - 19,109 SF
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$1,950,000
1536 E Army Post Rd
1536 E Army Post Rd, Easter Lake Area, Des Moines, IA
Property Type
Office
Built in 1973

17,781 SF
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2 of 2
$13.95/SF/YR
Capitol Center III
400 East Court Avenue, Historic East Village, Des Moines, IA
Space Type
Office
1 space

885 SF
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$17.00 - $18.00/SF/YR
Locust Plaza
1420 Locust Street, Downtown Des Moines, Des Moines, IA
Space Type
Office, Retail
4 spaces

2,230 - 7,689 SF
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$10.50 - $20.50/SF/YR
100 Court Office Building
100 Court Avenue, Downtown Des Moines, Des Moines, IA
Space Type
Office
7 spaces

1,247 - 5,412 SF
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$181,138,815,000
5402 SE 14th Street
5402 SE 14th Street, South Park, Des Moines, IA
Property Type
VacantLand
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$12.00 - $22.00/SF/YR
Chamberlain Building
1312 Locust Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
2 spaces

1,095 - 6,934 SF
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$11.75/SF/YR
300 East Locust Street
300 East Locust Street, Historic East Village, Des Moines, IA
Space Type
Office
5 spaces

1,000 - 7,139 SF
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$250.00 - $1,400.00/MO
Market Building
118 SE 4th Street, Historic East Village, Des Moines, IA
Space Type
Office
2 spaces

16,896 SF
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$1,510,000
2805 Beaver Ave
2805 Beaver Ave, Beaverdale, Des Moines, IA
Property Type
Retail
Built in 1966

5,054 SF
1 of 1
$11.00/SF/YR
Oakmoor North Office Building
4725 Merle Hay Road, Meredith, Des Moines, IA
Space Type
Office
2 spaces

1,013 - 1,733 SF
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From $29/day

Gravitate Coworking
Gravitate Coworking - Gravitate Downtown
500 Locust Street, Des Moines, IA
Space Type
Desks
Space for 1 person
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$1,350,000
310 Court Ave
310 Court Ave, Downtown Des Moines, Des Moines, IA
Property Type
Retail
Built in 1954

7,999 SF
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Price on request
909 Locust Street
909 Locust Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
3 spaces

3,886 - 22,000 SF
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$11.50/SF/YR
611 5th Avenue
611 5th Avenue, Downtown Des Moines, Des Moines, IA
Space Type
Office
1 space

20,280 SF
1 of 1
$9.75/SF/YR
1537 Vermont St
1537 Vermont St, Capitol Park, Des Moines, IA
Space Type
Industrial
1 space

4,200 SF
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2 of 3

3 of 3
$9.00 - $12.00/SF/YR
Capital Square
400 Locust Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
24 spaces

1,338 - 49,279 SF
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$1,600,000
Merle Hay Tower
3850 Merle Hay Road, Merle Hay, Des Moines, IA
Property Type
Office
Built in 1966

67,325 SF
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$16.00 - $22.00/SF/YR
Insurance Exchange Building
429 Grand Avenue, Downtown Des Moines, Des Moines, IA
Space Type
Office, Retail
10 spaces

1,042 - 12,165 SF
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Price on request
Gray's Lake Office Park - Building 1
220 SW 9th Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
1 space

6,228 SF
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$8,900,000
2500 Dixon Street
2500 Dixon Street, Fairmont Park, Des Moines, IA
Property Type
Industrial
Built in 1975

135,197 SF
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Price on request
800 Walnut Street
800 Walnut Street, Downtown Des Moines, Des Moines, IA
Space Type
Retail, Office
9 spaces

8,087 - 37,201 SF
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$16.50/SF/YR
Market One
130 East 3rd Street, Historic East Village, Des Moines, IA
Space Type
Office
3 spaces

3,000 - 5,500 SF
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$16.50/SF/YR
108 3rd Street
108 3rd Street, Downtown Des Moines, Des Moines, IA
Space Type
Office
3 spaces

10,611 SF

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Des Moines, IA Commercial Real Estate Market Overview: Key Trends & Insights

Des Moines has 15.7 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 200 properties.

This overview provides a snapshot of the Des Moines commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Des Moines, IA

Based on the latest estimates, Des Moines, IA offers almost 200 commercial listings for lease, totaling about 15.7 million square feet.

Current leasing options comprise 64 office listings, which represent approximately 53.33% out of the total leasing inventory. There are also 21 industrial and warehouse listings, making up 17.50% of the total. Additionally, 35 retail listings make up 29.17% of the local leasing market. These types are supplemented by 3 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 64 6,542,411 $12.84

Retail 35 1,329,007 $16.46

Industrial 21 3,276,197 $6.47

Other 3 13,143,455 N/A

Commercial Real Estate for Sale in Des Moines, IA

As of 2026, Des Moines, IA has a total of 80 commercial real estate properties for sale.

This inventory includes 17 office assets, 11 industrial facilities and 11 retail properties available for purchase.

The largest share is held by Office, with 21.25% out of local properties for sale belonging to this asset type. Retail has the next largest share at 13.75%, while Industrial makes up 13.75% of commercial properties for sale in Des Moines.

Property type No. of Listings Total Sq. Ft.

Office 17 6,542,411

Retail 11 1,329,007

Industrial 11 3,276,197

Other 41 45,049,172

Leading Commercial Real Estate Submarkets by Property Type in Des Moines, IA

The leading commercial real estate submarkets for different property types in Des Moines are:

Office: Downtown Des Moines with 99 office listings, totaling 1,121,152 square feet.
Industrial: Fairmont Park with 6 industrial listings, totaling 107,993 square feet.
Retail: Downtown Des Moines with 18 retail listings, totaling 54,443 square feet.