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For Lease

Peabody Place

112 S Duke St, Durham, NC 27701

27,153

SF Available

Rental Details

  • Number of spaces 5
  • Total square feet available 27,153 SF
  • For Lease Contact for pricing
  • Space Types Office, Flex - Office
  • Date Updated Apr 30, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 5 Spaces Available

#F110

  • Space Type Office
  • Lease Rate Contact for pricing
  • Total Space Available 8,130 SF
  • Floor 1
  • Divisible Space 1,349 - 15,785 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

CAN BE COMBINED WITH SUITE F-120 FOR 15,785 SF.

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

#F120

  • Space Type Office
  • Lease Rate Contact for pricing
  • Total Space Available 7,655 SF
  • Floor 1
  • Divisible Space 7,655 - 15,785 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No
  • Turnkey Yes

• Space: 7,655 RSF • 6 Private offices • 4 Conference rooms • Mezzanine level with full first floor • Flexible open collaboration areas • Turn-key and fully furnished • Open tenant kitchen and lounge area on first floor.

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

#F200

  • Space Type Office
  • Lease Rate Contact for pricing
  • Total Space Available 2,000 SF
  • Floor 2
  • Divisible Space 2,000 - 4,079 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

CAN BE COMBINED WITH SUITE F-210 FOR 4,079 SF.

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

#F210

  • Space Type Office
  • Lease Rate Contact for pricing
  • Total Space Available 2,079 SF
  • Floor 2
  • Divisible Space 2,079 - 4,079 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

CAN BE COMBINED WITH SUITE F-200 FOR 4,079 SF.

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

#FB00

  • Space Type Flex - Office
  • Lease Rate Contact for pricing
  • Total Space Available 7,289 SF
  • Additional Space Types R&D - Office, Life Sciences
  • Divisible Space 7,289 - 7,289 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

State-of-the-Art Life Sciences Laboratory

Purpose-built facility featuring

specialized biology and chemistry labs

totaling over 4,000 SF of dedicated

research space.

Flexible Research Infrastructure

Equipped with 300+ linear feet of

benchwork across multiple lab areas,

providing ample workspace for diverse

research activities and equipment

placement

Advanced Environmental Controls

Features dedicated mechanical systems

including a 4°C cold room, growth

chambers, and specialized HVAC with

exhaust ductwork to roof for optimal

research conditions

Complete Support Amenities

Includes essential laboratory support

functions such as autoclave facilities,

glass wash area, equipment storage, and

separate men’s and women’s restrooms

within the space.

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

Contacts

broker
John MacDonell

Jones Lang LaSalle

broker
Taylor McCuiston

Jones Lang LaSalle

Building Details

  • For Lease Contact for pricing
  • Property Type Office
  • Property Size 27,153 SF
  • Lot Size 0.59 Acre
  • Year Built 1910
  • Date Updated Apr 30, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (94)
  • Transit Score ®

    Good Transit (65)
  • Bike Score ®

    Very Bikeable (82)
Powered by Walk Score ®

Location

  • City Durham, NC
  • Neighborhood Downtown Durham
  • Zip Code 27701
  • Market Raleigh Durham

Points of Interest

Shell

0.20 miles

Gazelle

0.46 miles

Trinty Food Mart #4

0.59 miles

BP

0.80 miles

West Durham BP #450

0.90 miles

Forest Hills Tire Service Center

1.04 miles

In & Out Food Mart

1.16 miles

EVgo

6.02 miles

Chargepoint

8.52 miles

AmTrak Overnight Parking

0.21 miles

Durham Centre Garage

0.32 miles

North Parking Deck

0.33 miles

Corcoran Street Garage and Lot

0.33 miles

Smith Warehouse Parking Lot South

0.40 miles

Smith Warehouse Parking Lot North

0.40 miles

South Parking Deck

0.49 miles

Chapel Hill Street Garage

0.53 miles

Hertz Rental Car

1.74 miles

Sheetz Car Wash

3.08 miles

Lightning McClean Car Wash

3.57 miles

Autobell Car Wash

7.34 miles

Avis

8.05 miles

Budget

8.05 miles

AutoBell Car Wash

8.45 miles

Enterprise

8.58 miles

Autobath

9.14 miles

El Rodeo

0.07 miles

Maverick's Smokehouse and Taproom

0.09 miles

It’s a Southern Thing

0.10 miles

Rose's Meat Market and Sweet Shop

0.11 miles

Mount Fuji

0.12 miles

The Little Dipper

0.12 miles

Goorsha

0.13 miles

Skewers Bar and Grill

0.19 miles

Gonza Tacos y Tequila

0.19 miles

Durham Co-op Market

0.47 miles

Whole Foods Market

0.86 miles

Compare Foods

0.97 miles

Harris Teeter

1.13 miles

Food Lion

1.30 miles

Los Primos Supermarket

1.40 miles

Northgate Shopping Mall

1.41 miles

Red White Grocery

1.81 miles

Ross

1.96 miles

Durham Fire Station Number 1

0.65 miles

Duke University Police

0.99 miles

Durham Fire Station Number 2

1.29 miles

Lincoln Community Health Center

1.42 miles

Pickens Building

1.50 miles

Duke Clinic

1.57 miles

Duke Psychiatry

1.60 miles

Duke Cancer Center

1.63 miles

Duke Medicine Pavillion

1.64 miles

112 S Duke St Listing Summary

  • Office Space Available at 112 S Duke St

    Office space currently available at 112 S Duke St adds up to a total of 27,153 square feet across 5 listing(s). The largest individual space listed offers 8,130 square feet. Property use types available for lease at this property include: office and flex - office.

  • Learn More about 112 S Duke St

    112 S Duke St is located in the Raleigh Durham market and pertains to the 27701 zip code. The property incorporates a total of 27,153 square feet of space. 112 S Duke St was built in 1910.

    Interested in researching more about this property? Access in-depth research on 112 S Duke St, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Downtown Durham neighborhood, where 112 S Duke St is located, you can currently find 56 office space(s) for rent. In total, this amounts to 560,669 square feet of available office space for lease opportunities.

Contact Peabody Place
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