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For Lease

Atrium Two

221 East 4th Street, Cincinnati, OH 45202

88,710

SF Available

Rental Details

  • Number of spaces 8
  • Total square feet available 88,710 SF
  • For Lease $12.50 - $19.00/SF/YR
  • Space Types General Office
  • Lease Type Net
  • Date Updated Feb 23, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 8 Spaces Available

#1900

  • Space Type General Office
  • Lease Rate $13.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 11,288 SF
  • Floor 19
  • Divisible Space 11,288 - 13,508 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#1930

  • Space Type General Office
  • Lease Rate $13.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 2,220 SF
  • Floor 19
  • Divisible Space 2,220 - 13,508 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#2000

  • Space Type General Office
  • Lease Rate $13.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 7,401 SF
  • Floor 20
  • Divisible Space 7,401 - 7,401 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#2150

  • Space Type General Office
  • Lease Rate $15.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 9,098 SF
  • Floor 21
  • Divisible Space 9,098 - 9,098 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#2400

  • Space Type General Office
  • Lease Rate $15.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 7,152 SF
  • Floor 24
  • Divisible Space 7,152 - 7,152 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#2750

  • Space Type General Office
  • Lease Rate $19.00/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 4,012 SF
  • Floor 27
  • Divisible Space 4,012 - 4,012 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
  • Turnkey Yes
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#300

  • Space Type General Office
  • Lease Rate $12.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 7,415 SF
  • Floor 3
  • Divisible Space 7,415 - 7,415 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

#700

  • Space Type General Office
  • Lease Rate $12.50/SF/YR
  • Additional Rent $10.50/SF/YR
  • Total Space Available 40,124 SF
  • Floor 7
  • Divisible Space 40,124 - 40,124 SF
  • Available Date Immediate
  • Lease Type Net
  • Renewal Option Yes
  • Sublease No
broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

Contacts

broker
John J. Cranley

Keating Muething & Klekamp

broker
Hannah Staubach

CBRE

broker
Scott Yards

CBRE

broker
Travis Likes

CBRE

Building Details

  • For Lease $12.50 - $19.00/SF/YR
  • Property Type Office - General Office
  • Property Size 655,863 SF
  • Lot Size 1.22 Acre
  • Parking Spaces Avail. 157
  • Parking Ratio 0.24 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • LEED Certified Gold
  • Building Class A
  • Year Built 1984
  • Date Updated Feb 23, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (94)
  • Transit Score ®

    Excellent Transit (80)
  • Bike Score ®

    Bikeable (62)
Powered by Walk Score ®

Location

  • City Cincinnati, OH
  • Neighborhood Downtown Cincinnati
  • Zip Code 45202
  • Market Cincinnati
  • Map
  • Street

Points of Interest

Fountain Square

0.15 miles

The Banks

0.15 miles

6th & Main

0.22 miles

Aronoff Center

0.32 miles

8th & Main

0.36 miles

Public Library

0.40 miles

Court & Main

0.49 miles

Central Parkway

0.56 miles

Hanke Exchange

0.58 miles

FLO

1.20 miles

Daniels Street Fast Charger

2.18 miles

Top Up Mart Fuel

2.28 miles

Clifton Court Garage Charging Station

2.40 miles

BP

2.80 miles

Speedway

3.10 miles

Kroger Gas

3.41 miles

UDF Fuel

3.82 miles

Tesla Supercharger

6.16 miles

Columbia Plaza

0.13 miles

Olympic Auto Park

0.16 miles

Western and Southern Building

0.17 miles

Broadway Lot

0.20 miles

Fountain Square Parking

0.21 miles

Central Riverfront Garage

0.23 miles

Seven at Broadway

0.28 miles

The Mabley Place Garage

0.28 miles

East Garage

0.31 miles

Zipcar

0.48 miles

Mister Bubbles Complete Care Detailing

0.74 miles

Enterprise

4.27 miles

Mike's Carwash

6.04 miles

United Dairy Farmers

6.34 miles

Whitewater Express Car Wash

6.41 miles

Self Service Car Wash

6.50 miles

Soft Cloth Car Wash

6.53 miles

Rainbow Car Wash

6.97 miles

Corner Bistro

0.06 miles

Wild Eggs

0.08 miles

Burrito Joe’s

0.13 miles

Currito

0.14 miles

Subway

0.14 miles

Galla Park

0.15 miles

LaRosa's Pizzeria

0.18 miles

Dunkin'

0.19 miles

Ingredients

0.19 miles

Kroger on the Rhine

0.49 miles

SolarPanelsCincinnati.com

0.53 miles

Kroger

1.95 miles

Target

1.97 miles

Clifton Market

3.03 miles

Whole Foods Market

4.55 miles

Save-A-Lot

4.74 miles

Walmart Supercenter

5.15 miles

Kohl's

5.51 miles

Cincinnati Police Welcome Center

0.21 miles

CVS Pharmacy

0.32 miles

Fire Station 3

0.41 miles

Hamilton County Sheriff’s Office

0.43 miles

Number 14 Engine House

0.55 miles

Over-the-Rhine MediCenter

0.58 miles

District 1 Police Station

0.91 miles

Crossroad Health Center

0.93 miles

Pharmacy Over-the-Rhine

0.93 miles

221 East 4th Street Listing Summary

  • Office Space Available at 221 East 4th Street

    Office space currently available at 221 East 4th Street adds up to a total of 88,710 square feet across 8 listing(s). The largest individual space listed offers 40,124 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 221 East 4th Street

    221 East 4th Street is located in the Cincinnati market and pertains to the 45202 zip code. The property incorporates a total of 88,710 square feet of space. Within the same building, there are 88,710 square feet of space. 221 East 4th Street features a parking ratio of 0.24 / 1,000 SF, offering a total of 157 parking spaces. 221 East 4th Street was built in 1984.

    Interested in researching more about this property? Access in-depth research on 221 East 4th Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Downtown Cincinnati neighborhood, where 221 East 4th Street is located, you can currently find 210 office space(s) for rent. In total, this amounts to 2,400,897 square feet of available office space for lease opportunities.

Contact Atrium Two
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