Stand Alone Medical & Office Building
4101 Main St, Suites E & F , Hilton Head Island, SC 29926
7,200
SF AvailableKey features
- Recently vacated, the building is ready for immediate tenant improvements or occupancy, offering an ideal setting for medical or wellness users seeking a convenient and professional island location.
- Suite E consists of reception/waiting area, 3-4 offices, conference room, storage and restroom.
- Suite F consists of waiting room, nursing/business area, +/- 7 exams rooms, break room and restroom.
- The property provides easy access to Hilton Head Hospital, the surrounding professional area, and nearby Bluffton.
- Very attractive stand-alone medical office building located on Main Street on the north end of Hilton Head Island, just off Highway 278.
Rental Details
- Number of spaces 3
- Total square feet available 7,200 SF
- For Lease $17.00 - $19.00/SF/YR
- Space Types General Office, Office, Medical Office
- Lease Type NNN
- Date Updated Apr 28, 2026
Reach out to the broker for more info on lease terms and amenities
True
For Lease 3 Spaces Available
E |
Baker Wilkins
NAI Carolina Charter |
E & F |
Baker Wilkins
NAI Carolina Charter |
F |
Baker Wilkins
NAI Carolina Charter |
Contacts
NAI Carolina Charter
Building Details
- For Lease $17.00 - $19.00/SF/YR
- Property Type Office - Medical Office
- Property Size 3,600 SF
- Lot Size 2.25 Acre
- Building Class A
- Year Built 2001
- Date Updated Apr 28, 2026
Attachments
Getting Around
-
Walk Score ®
Car-Dependent (46) -
Bike Score ®
Bikeable (65)
Location
- City Hilton Head Island, SC
- Zip Code 29926
Points of Interest
Speedway
1.49 miles
Kroger
2.31 miles
Shell
4.46 miles
Enmark
4.51 miles
ChargePoint
4.72 miles
Harris Teeter Fuel
4.77 miles
National
2.04 miles
Parris Island Car Wash
9.63 miles
Frankie Bones
0.47 miles
WiseGuys HHI
0.48 miles
The Crazy Crab Jarvis Creek
1.64 miles
Skull Creek Boathouse
1.74 miles
Skull Creek Dockside
1.75 miles
Reilley's North End Pub
1.76 miles
Hudson’s Seafood House on the Docks
1.80 miles
Poseidon
2.12 miles
Giuseppi's Pizza and Pasta
2.14 miles
Publix
0.48 miles
Harris Teeter
0.53 miles
Whole Foods Market
2.10 miles
TJ Maxx
2.13 miles
Kroger
2.14 miles
Belk
2.16 miles
The Fresh Market
3.15 miles
Piggly Wiggly
5.06 miles
Saks Fifth Avenue
6.29 miles
Hilton Head Island Fire / Rescue Station 4
0.99 miles
Hilton Head Hospital
1.15 miles
Hilton Head Island Fire / Rescue Station 3
2.05 miles
Hilton Head Island Airport Fire Station
2.18 miles
Hilton Head Island Fire / Rescue Station 7
2.58 miles
Hilton Head Island Fire / Rescue Station 6
2.76 miles
Station 6
2.76 miles
Walgreens
4.46 miles
CVS Pharmacy
4.66 miles
4101 Main St, Suites E & F Listing Summary
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Office Space Available at 4101 Main St, Suites E & F
Office space currently available at 4101 Main St, Suites E & F adds up to a total of 7,200 square feet across 3 listing(s). The largest individual space listed offers 3,600 square feet. Property use types available for lease at this property include: general office, office and medical office.
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Learn More about 4101 Main St, Suites E & F
The property incorporates a total of 7,200 square feet of space. 4101 Main St, Suites E & F was built in 2001.
Interested in researching more about this property? Access in-depth research on 4101 Main St, Suites E & F , including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.
NAI Carolina Charter
