Mount Pleasant, SC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

95 Listings

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From $949/month

Serendipity Labs
Serendipity Labs - Charleston Mount Pleasant
75 Port City Landing, Suite 110 and 200, Mount Pleasant, SC
Space Type
Private Offices
Space for 1 person
1 of 2

2 of 2
$180,000.00/SF/YR
N Highway 17
N Highway 17, Mount Pleasant, SC
Space Type
Land
1 space

200,376 SF
1 of 6

2 of 6

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6 of 6
Price on request
±6,000 - 85,000 SF Industrial Space Next to Wando Terminal
476 Long Point Rd, Mount Pleasant, SC
Space Type
Industrial
1 space

85,000 SF
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Price on request
Mount Pleasant Towne Centre
1218 Belk Drive, Mount Pleasant, Mt. Pleasant, SC
Space Type
Retail, Mixed Use
11 spaces

1,044 - 34,660 SF
1 of 4

2 of 4

3 of 4

4 of 4
$199,000
Blanche Darby Florist
581 Belle Station Boulevard, Mount Pleasant, SC
Property Type
Retail
1,200 SF
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Price on request
1125 Bowman Road
1125 Bowman Road, Mount Pleasant, SC
Space Type
Office
1 of 10

2 of 10

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$1,065,000
Portside Center
421 Wando Park Boulevard, Suite 100, Mount Pleasant, SC
Property Type
Office
4,730 SF
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2 of 5

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5 of 5
$3,000,000
Commercial Lease/Sale
1161 SC-41, Mount Pleasant, SC
Property Type
Office
8,748 SF
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$21.50 - $22.50/SF/YR
Riverside Center
496 La Mesa Street, Mount Pleasant, SC
Space Type
Industrial
6 spaces

1,003 - 5,009 SF
1 of 2

2 of 2
Price on request
Multiple Suites Available for Lease | Medical Office Building
1300 Hospital Dr, Mount Pleasant, SC
Space Type
Office
1 space

3,425 SF
1 of 4

2 of 4

3 of 4

4 of 4
$32.00/SF/YR
Belle Hall II
1671 Belle Isle Avenue, Mount Pleasant, SC
Space Type
Office
3 spaces

2,227 - 8,582 SF
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2 of 6

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$35.73/SF/YR
The Tides Medical Arts Center
180 Wingo Way, Mount Pleasant, SC
Space Type
Office
1 space

1,376 SF
1 of 2

2 of 2
Price on request
Indigo Square
US 17 and Indigo Market Drive , Mount Pleasant, Mt Pleasant, SC
Space Type
Retail
1 space

830 SF
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Price on request
Mount Pleasant Medical Office Longpoint
570 Long Point Road, Mount Pleasant, SC
Space Type
Office
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$38.00/SF/YR
Adjacent to Grocery Anchor
615 Johnnie Dodds Blvd, Mount Pleasant, SC
Space Type
Retail
1 space

4,261 SF
1 of 4

2 of 4

3 of 4

4 of 4
$42.00/SF/YR
Gateway Mount Pleasant
235 Magrath Darby Blvd, Mount Pleasant, SC
Space Type
Office
1 space

5,707 SF
1 of 2

2 of 2
Price on request
Queensborough Shopping Center
1000 Johnnie Dodds Blvd, Mount Pleasant, SC
Space Type
Retail
2 spaces

1,500 - 3,993 SF
1 of 3

2 of 3

3 of 3
From $1,300/month

Office Evolution
Mount Pleasant Office Evolution
1501 Belle Isle Avenue Suite 110, Mount Pleasant, SC
Space Type
Private Offices
Space for up to 3 people
1 of 2

2 of 2
$725,000
High Visibility 1 Acre Site in Mount Pleasant
245 Crystal Dr, Mount Pleasant, SC
Property Type
VacantLand
1 of 3

2 of 3

3 of 3
Price on request
627 Hwy 17 N
627 Hwy 17 N, Mount Pleasant, SC
Space Type
Mixed Use
1 space

392,475.6 SF
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2 of 6

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6 of 6
Price on request
450 Wando Park Blvd
450 Wando Park Blvd, Mount Pleasant, SC
Space Type
Industrial
1 space

154,840 SF
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Price on request
±17,349 SF Full-Floor Office Condo For Sale and Lease
421 Wando Park Blvd, Mount Pleasant, SC
Space Type
Office
1 space

17,349 SF
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$20.50/SF/YR
890 Johnnie Dodds Blvd
890 Johnnie Dodds Blvd, Mount Pleasant, SC
Space Type
Office
1 space

1,700 SF
1 of 10

2 of 10

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$1,500.00/MO
1455 Wakendaw Road
1455 Wakendaw Road, Mount Pleasant, SC
Space Type
Mixed Use
3 spaces

220 - 403 SF
1 of 5

2 of 5

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5 of 5
Price on request
±2,611 SF for Sublease at the foot of the Ravenel Bridge in Mt. Pleasant
75 Port City Lndg, Mount Pleasant, SC
Space Type
Office
1 space

3,200 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
$795.00 - $825.00/MO
845 Lowcountry Blvd
845 Lowcountry Blvd, Mount Pleasant, SC
Space Type
Office
3 spaces

172 - 215 SF
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$1,740,500
260 W Coleman Blvd
260 W Coleman Blvd, Mount Pleasant, SC
Property Type
Office
4,365 SF
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2 of 8

3 of 8

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$6,470,000
±17,349 SF Full-Floor Office Condo For Sale and Lease
421 Wando Park Blvd, Mount Pleasant, SC
Property Type
Office
Built in 2006

30,000 SF
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2 of 3

3 of 3
$41.00/SF/YR
735 Johnnie Dodds
735 Johnnie Dodds Blvd, Mount Pleasant, SC
Space Type
Office
1 space

588 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
$1,510,500
±1.59-Acre Outparcel in Lowe’s-Anchored Shopping Center | Mount Pleasant, SC
2100 Hwy 41, Mount Pleasant, SC
Property Type
Other
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$21.00 - $24.00/SF/YR
Wando Commons
498 Wando Park Blvd, Mount Pleasant, SC
Space Type
Office
3 spaces

1,485 - 2,263 SF
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$3,250.00/MO
732 S Shelmore
732 South Shelmore Boulevard #100, Mount Pleasant, SC
Space Type
Retail
1 space

900 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
From $600/month

I3 Real Estate
Tide & Table, LLC
1007 Johnnie Dodds Boulevard, Mount Pleasant, SC
Space Type
Private Offices
Space for up to 2 people
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From $649/month

Regus
Gregorie Ferry Landing
1240 Winnowing Way Suite 100, Mount Pleasant, SC
Space Type
Private Offices
Space for 1 to 50 people
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2 of 2
Price on request

CEO
1156 Bowman Road
1156 Bowman Road #200, Mount Pleasant, SC
Space Type
Private Offices
1 of 2

2 of 2
From $800/month

InnoLabs
InnoLabs - 1007 Johnnie Dodds Boulevard
1007 Johnnie Dodds Boulevard #122, Mount Pleasant, SC
Space Type
Private Offices
$2,600,000
1124 Park West Boulevard
1124 Park West Boulevard, Mount Pleasant, SC
Property Type
Office
6,984 SF
From $650/month

Charleston Office Rentals
Building 5
3015 Dunes West Boulevard #502, Mount Pleasant, SC
Space Type
Private Offices
Price on request
550 Long Point Rd
550 Long Point Rd, Mount Pleasant, SC
Space Type
Office
2 spaces

4,740 - 5,540 SF
$36.00/SF/YR
Six Mile Marketplace
2195 Tea Planter Lane, Mount Pleasant, SC
Space Type
Retail
2 spaces

1,486 - 1,489 SF

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Mount Pleasant, SC Commercial Real Estate Market Overview: Key Trends & Insights

Mount Pleasant has 1.2 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 100 properties.

This overview provides a snapshot of the Mount Pleasant commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Mount Pleasant, SC

Based on the latest estimates, Mount Pleasant, SC offers almost 100 commercial listings for lease, totaling about 1.2 million square feet.

Current leasing options comprise 34 office listings, which represent approximately 60.71% out of the total leasing inventory. There are also 3 industrial and warehouse listings, making up 5.36% of the total. Additionally, 19 retail listings make up 33.93% of the local leasing market. These types are supplemented by 6 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 34 567,178 N/A

Retail 19 616,740 $38.36

Industrial 3 466,461 N/A

Other 6 732,295 N/A

Commercial Real Estate for Sale in Mount Pleasant, SC

As of 2026, Mount Pleasant, SC has a total of 26 commercial real estate properties for sale.

This inventory includes 14 office assets, 3 industrial facilities and 2 retail properties available for purchase.

The largest share is held by Office, with 53.85% out of local properties for sale belonging to this asset type. Industrial has the next largest share at 11.54%, while Retail makes up 7.69% of commercial properties for sale in Mount Pleasant.

Property type No. of Listings Total Sq. Ft.

Office 14 567,178

Retail 2 616,740

Industrial 3 466,461

Other 7 612,460