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For Lease

425 Eccles Ave

425 Eccles Ave, South San Francisco, CA 94080

20,935

SF Available

Rental Details

  • Number of spaces 1
  • Total square feet available 20,935 SF
  • For Lease $4.00/SF/MO
  • Space Types Life Sciences
  • Lease Type Full Service
  • Date Updated May 5, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

Full Building

  • Space Type Life Sciences
  • Lease Rate $4.00/SF/MO
  • Total Space Available 20,935 SF
  • Divisible Space 20,935 - 20,935 SF
  • # Of Parking Spaces 49
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
  • Turnkey Yes

±42,253 SF lot with ±49 parking spaces

Glass line around entire building with large open lab areas, dedicated back up power, floor drains

Casework & 6 ft. chemical fume hoods in each of the labs

Office & Lab Furniture available/ Plug & Play

Multiple Conference rooms and large Amenity Eating Lounge

Partial Lab Equipment could be made available for Tenants use

Ample Private Storage/Haz Mat Rooms and Shipping & Receiving areas

Back up Generator with Ample power

Lease Rate: Inquire with Broker

Walkable to CalTrain station

broker
Joseph Cammarata

Kidder Mathews

broker
Eric DeBrine

Kidder Mathews

Contacts

broker
Joseph Cammarata

Kidder Mathews

broker
Eric DeBrine

Kidder Mathews

Building Details

  • For Lease $4.00/SF/MO
  • Property Type Office - Life Sciences
  • Property Size 20,935 SF
  • Lot Size 0.97 Acre
  • Parking Spaces Avail. 49
  • Parking Ratio 2.34 / 1,000 SF
  • Building Class C
  • Year Built 1975
  • Date Updated May 5, 2026

Getting Around

  • Walk Score ®

    Car-Dependent (41)
  • Bike Score ®

    Somewhat Bikeable (48)
Powered by Walk Score ®

Location

  • City South San Francisco, CA
  • Neighborhood The East Side
  • Zip Code 94080
  • Market San Francisco

Points of Interest

San Bruno

1.79 miles

West Field Road

2.50 miles

South San Francisco

2.69 miles

Taxi Stand at SFO, Domestic Terminal 3 (Arrivals Level in front of Door 5, 6, 7, 8, 9, 10)

2.80 miles

Terminal 3

2.82 miles

San Francisco International Airport (SFO)

2.87 miles

San Francisco International Airport

2.88 miles

Taxi Stand at SFO, Domestic Terminal 2 (Arrivals Level in front of Door 1, 2, 3, 4)

2.89 miles

Taxi Stand at International Arrivals SFO

2.91 miles

Blink

0.39 miles

Speedway

0.53 miles

Shell

0.54 miles

76

0.73 miles

Chico's

0.79 miles

True Zero

0.88 miles

Valero

0.98 miles

EV Range

1.05 miles

Fathom Marine

1.05 miles

United Airlines East Parking Lot

1.41 miles

SFO Long-Term Parking Garage #1

1.49 miles

SFO Long-Term Parking Garage #2

1.57 miles

Cell Phone Waiting Lot

1.65 miles

SFO TNC Staging Lot 3

1.69 miles

SFO Long-Term Parking

1.69 miles

Charter Bus Staging Lot

1.70 miles

Worksite Labs Testing Site at SFO

1.73 miles

Taxi Staging Lot

1.74 miles

Advantage Rent A Car

1.10 miles

Fox Rent a Car

1.13 miles

Hertz

2.02 miles

Enterprise

2.02 miles

Alamo

2.02 miles

Dollar

2.04 miles

Budget

2.04 miles

SIXT Rent a Car San Francisco Int Airport

2.04 miles

Avis

2.06 miles

HL Peninsula Restaurant

0.53 miles

Taqueria Celaya

0.73 miles

Amoura

0.73 miles

Pronto's

0.74 miles

Dumpling Empire

0.74 miles

Cafe Bunn Mi

0.77 miles

KFC

0.77 miles

Taco Bell

0.77 miles

Sky Cafe

0.77 miles

Safeway

1.80 miles

Target

1.86 miles

Lucky

1.88 miles

Marshalls

1.89 miles

The Shops at Tanforan

1.93 miles

JCPenney

1.95 miles

Smart & Final

1.99 miles

Pacific Supermarket

2.19 miles

Besan’s International Market

2.49 miles

San Bruno Police Department

1.80 miles

SFO Marine Emergency Response Facility

1.95 miles

Walgreens

1.97 miles

Brisbane Police Department

2.06 miles

South San Francisco Police Department

2.08 miles

Brisbane Fire Department

2.09 miles

SFO Police Training Facility

2.12 miles

Fire Station 63

2.27 miles

SFO Fire Station 1

2.33 miles

425 Eccles Ave Listing Summary

  • Office Space Available at 425 Eccles Ave

    Office space currently available at 425 Eccles Ave adds up to a total of 20,935 square feet across 1 listing(s). The largest individual space listed offers 20,935 square feet. Property use types available for lease at this property include: life sciences.

  • Learn More about 425 Eccles Ave

    425 Eccles Ave is located in the San Francisco market and pertains to the 94080 zip code. The property incorporates a total of 20,935 square feet of space. 425 Eccles Ave features a parking ratio of 2.34 / 1,000 SF, offering a total of 49 parking spaces. 425 Eccles Ave was built in 1975.

    Interested in researching more about this property? Access in-depth research on 425 Eccles Ave, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the The East Side neighborhood, where 425 Eccles Ave is located, you can currently find 62 office space(s) for rent. In total, this amounts to 1,463,967 square feet of available office space for lease opportunities.

Contact 425 Eccles Ave
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