• Resources
    • Learning Center
    • Blog
Add a Listing Advertise
  • Property Lists
  • Listings
    • Commercial Real Estate
  • Comparables
  • Owners
  • Maps
  1. Industrial Space
  2. MO
  3. Cape Girardeau
  • Map
  • Street

Map of Property

  • Details
  • Spaces Available
  • Contacts
  • Location
  • POI
For Lease

500 William St

500 William St, Cape Girardeau, MO 63703

21,984

SF Available
Situated in the heart of Cape Girardeau's industrial corridor, 500 William Street offers convenient access to major transportation routes, suppliers, and workforce populations throughout Southeast Missouri, Southern Illinois, and Western Kentucky. The property's central location provides efficient connectivity to Interstate 55, US Highway 61, and regional logistics networks, making it an ideal location for manufacturing, assembly, distribution, and industrial service operations.Flexible industrial space available for lease at 500 William Street in Cape Girardeau, Missouri. The property offers approximately 11,000 SF of total industrial space that can be leased in its entirety or demised into four individual suites ranging from approximately 2,000 SF to 3,300 SF. (make sure to check out the "Spaces" tab above to see each space) Designed for manufacturing and industrial users, the facility features commercial-grade power infrastructure, heavy-duty concrete floors capable of supporting machinery and equipment, and access to a shared loading dock with dedicated loading capabilities for each tenant. The flexible configuration allows tenants to lease only the space they need today while maintaining the opportunity to expand as operations grow. This property is ideally suited for manufacturing, fabrication, assembly, warehousing, distribution, contractor operations, and other industrial users seeking functional space in a strategic Cape Girardeau location.

Key features

  • Centrally located in Cape Girardeau
  • Commercial-grade electrical service
  • Dedicated dock door access for tenants
  • Excellent access to regional transportation corridors
  • Flexible expansion opportunities within the building
  • Four available industrial suites ranging from approximately 2,000 SF to 3,300 SF
  • Functional industrial layout
  • Heavy-duty concrete floors designed for industrial equipment and machinery
  • Ideal for manufacturing, fabrication, assembly, and distribution users
  • Lease individual suites or the entire facility
  • Manufacturing and industrial-zoned facility
  • Rare small-bay industrial leasing opportunity
  • Shared loading dock access
  • Suitable for owner-operated businesses, startups, and expanding manufacturers
  • Up to approximately 11,000 SF available

Rental Details

  • Number of spaces 5
  • Total square feet available 21,984 SF
  • For Lease $8.50/SF/YR
  • Space Types Warehouse/Distribution, Manufacturing, Flex - Industrial
  • Lease Type Full Service
  • Date Updated Jun 6, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 5 Spaces Available

500 William Suite A

  • Space Type Warehouse/Distribution
  • Lease Rate $8.50/SF/YR
  • Total Space Available 2,093 SF
  • Divisible Space 2,093 - 2,093 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Standard utility usage is included.

broker
Matt Huber

Lorimont Commercial Real Estate

500 William Suite B

  • Space Type Manufacturing
  • Lease Rate $8.50/SF/YR
  • Total Space Available 3,311 SF
  • Divisible Space 3,311 - 3,311 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Standard utility usage included.

broker
Matt Huber

Lorimont Commercial Real Estate

500 William Suite C

  • Space Type Flex - Industrial
  • Lease Rate $8.50/SF/YR
  • Total Space Available 2,483 SF
  • Divisible Space 2,483 - 2,483 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Standard utility usage included

broker
Matt Huber

Lorimont Commercial Real Estate

500 William Suite D

  • Space Type Flex - Industrial
  • Lease Rate $8.50/SF/YR
  • Total Space Available 3,105 SF
  • Divisible Space 3,105 - 3,105 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Standard utility usage included

broker
Matt Huber

Lorimont Commercial Real Estate

500 William Suites A-D

  • Space Type Flex - Industrial
  • Lease Rate $8.50/SF/YR
  • Total Space Available 10,992 SF
  • Divisible Space 10,992 - 10,992 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No

Standard utility usage included

broker
Matt Huber

Lorimont Commercial Real Estate

Contacts

broker
Matt Huber

Lorimont Commercial Real Estate

Building Details

  • For Lease $8.50/SF/YR
  • Property Type Industrial - Warehouse/Distribution
  • Property Size 29,752 SF
  • Lot Size 1.5 Acre
  • Date Updated Jun 6, 2026
  • HVAC None

Attachments

  • Property Brochure 1 ()opens in new window
  • Property Brochure 2 ()opens in new window

Getting Around

  • Walk Score ®

    Somewhat Walkable (64)
  • Bike Score ®

    Bikeable (55)
Powered by Walk Score ®

Location

  • City Cape Girardeau, MO
  • Zip Code 63703

Points of Interest

Jackson

9.41 miles

Iron Moountain Junction

9.62 miles

Rhodes

2.69 miles

Mobil

3.19 miles

Rhodes Travel Center

4.66 miles

Church overflow parking

5.59 miles

Southeast Hospital

1.13 miles

Walgreens

1.55 miles

Southeast Behavioral Hospital

2.44 miles

Saint Francis Medical Center

2.53 miles

MediCenter Pharmacy

2.68 miles

Cape Girardeau Station 4

3.39 miles

Autism Support Now

3.41 miles

Scott City Police Department

5.67 miles

Scott City Fire Department Station 1

5.67 miles

Port Cape Girardeau Restaurant and Lounge

0.47 miles

Hardee's

1.34 miles

McDonald's

1.39 miles

Arby's

1.48 miles

Fazoli's

1.54 miles

Wendy's

1.54 miles

Watami Sushi & Hibachi Steakhouse

1.55 miles

Long John Silver's

1.55 miles

Captain D's

1.56 miles

500 William St Listing Summary

  • The Price for Industrial Space at 500 William St

    As is true of most real estate, the asking price for industrial space can vary based on factors such as the property location, proximity to transportation and shipping hubs, the property age, quality rating, and onsite facilities and features. At 500 William St, the asking rate is $8.50/SF/YR.

  • Industrial Space Options at 500 William St

    The facility offers a total of 29,752 square feet of rentable industrial space. Leasing opportunities here include Warehouse/Distribution space, Manufacturing space, Flex - Industrial space.

  • Key Amenities and Features at 500 William St

    The property at 500 William St features climate-control technology, and more.

Contact Listing Broker
broker
Matt Huber

Lorimont Commercial Real Estate

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Nearby Listings

Warehouse For Lease

Warehouse For Lease

211 N. Spring Ave., Unit C, Cape Girardeau, MO
$6.00/SF/YR
Property
  • Industrial
  • 13,875 SF
Availability
  • 1 Space
  • 13,875 SF
45 N Broadview St - Middle

45 N Broadview St - Middle

45 N Broadview St - Middle, Cape Girardeau, MO
$3,000.00/MO
Property
  • Industrial
  • 5,100 SF
Availability
  • 1 Space
  • 5,100 SF
2285 Sacajawea Lane

2285 Sacajawea Lane

2285 Sacajawea Lane, Cape Girardeau, MO
$3,250.00/MO
Property
  • Industrial
  • 4,576 SF
Availability
  • 1 Space
  • 4,576 SF
15,200 SF Shop Building Off I-55

15,200 SF Shop Building Off I-55

3141 E. Outer Road, Scott City, MO
$15,833.00/MO
Property
  • Industrial
  • 15,200 SF
Availability
  • 1 Space
  • 15,200 SF
3,310 SF Warehouse/Shop Building

3,310 SF Warehouse/Shop Building

5841 County Road 205, Cape Girardeau, MO
Contact for pricing
Property
  • Industrial
  • 3,310 SF
Availability
  • 1 Space
  • 3,310 SF

Popular Searches

  • Saint Louis Industrial Space for Lease
  • Cape Girardeau Industrial Space for Lease
  • Saint Louis Commercial Real Estate
  • Cape Girardeau Commercial Real Estate
  • Jackson Commercial Real Estate
  • Scott City Commercial Real Estate
  • Saint Louis Office Space for Rent
  • Cape Girardeau Office Space for Rent
Copyright 2003-2026, PropertyShark.com
Contact Us  |  About  |  Privacy Policy  |  Terms Of Service  |  Sitemaps