Saint Louis, MO Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

384 Listings

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$10.00/SF/YR
Farmer's Merchant
3550-3552 Gravois Ave, Gravois Park, Saint Louis, MO
Space Type
Retail
2 spaces

870 - 1,135 SF
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$2,242,000
5739 Natural Bridge Avenue
5739 Natural Bridge Avenue, Mark Twain - I-70 Industrial, St. Louis, MO
Property Type
Industrial
118,000 SF
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$1,595,000
Iconic Restaurant Opportunity
4652 Shaw Avenue St. Louis, Southwest Garden, St. Louis, MO
Property Type
Retail
Built in 1905

5,687 SF
1 of 1
$245,000
Prime Development Site At Kingshighway & Gravois
6601 South Kingshighway Boulevard St. Louis, Princeton Heights, St. Louis, MO
Property Type
Land
0.38 Acre
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Premium commercial
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$16.00/SF/YR
South Grand Creative Office
3030 South Grand Boulevard, Tower Grove East, St. Louis, MO
Space Type
Office
1 space

4,000 SF
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$15.00/SF/YR
S. Kingshighway 2nd Floor Office Space
1151 S Kingshighway Blvd, Kings Oak, Saint Louis, MO
Space Type
Office
1 space

2,500 SF
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From $299/month

Regus
Regus - St Louis - Lami
1031 Lami Street, St. Louis, MO
Space Type
Private Offices
Space for 1 to 15 people
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2 of 2
Price on request
Security Building
319 N 4th Street, Downtown Saint Louis, St Louis, MO
Space Type
Office
2 spaces

2,830 - 4,610 SF
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Price on request
840 East Taylor Avenue
840 East Taylor Avenue, North Riverfront, St. Louis, MO
Property Type
Industrial
Built in 1920

96,039 SF
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$5.85/SF/YR
St. Louis Business Center
8000 Hall Street, North Riverfront, St. Louis, MO
Space Type
Industrial
2 spaces

12,480 - 47,874 SF
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Price on request
Metropolitan Flats Retail
4561 Forest Park Avenue, Central West End Saint Louis, St. Louis, MO
Space Type
Retail
1 space

5,477 SF
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2 of 2
$1.25/SF/MO
4410 Hunt Avenue
4410 Hunt Avenue, Forest Park South East, St. Louis, MO
Space Type
Industrial
1 space

25,000 SF
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From $329/month

HQ
MO, St Louis - Union Boulevard
303 Union Boulevard 2nd Floor, St. Louis, MO
Space Type
Private Offices
Space for 1 to 15 people
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$11.95 - $13.95/SF/YR
1430 Olive Street
1430 Olive Street, Downtown West Saint Louis, St. Louis, MO
Space Type
Office
1 space

42,300 SF
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$28.00/SF/YR
The Nicholas
1500-1506 s. grand St. Louis, The Gate District, St. Louis, MO
Space Type
Retail
1 space

1,245 SF
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From $20/day

TechArtista
TechArtista - Downtown
401 Pine Street , St. Louis, MO
Space Type
Desks
Space for up to 10 people
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$300,000
1907 Locust Street
1907 Locust Street, Downtown West Saint Louis, St. Louis, MO
Property Type
Retail
Built in 1925

5,040 SF
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$1,900,000
22,000 S.F. Midtown Building
1900 Locust Street St. Louis, Downtown West Saint Louis, St. Louis, MO
Property Type
Retail
Built in 1890

21,390 SF
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$12.50/SF/YR
Security Building
319 N 4th St, Downtown Saint Louis, St. Louis, MO
Space Type
Office
21 spaces

170 - 11,119 SF
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2 of 2
Subject To Offer
1130 & 1144 Hampton Avenue
1130 & 1144 Hampton Avenue, Cheltenham, St. Louis, MO
Property Type
Office
63,369 SF
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Price on request
Marquette Building
300-314 N Broadway, Downtown Saint Louis, Saint Louis, MO
Space Type
Retail, Office
5 spaces

3,167 - 13,376 SF
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$12.00/SF/YR
Delmar Blvd Office/Retail for Lease
5606-5610 Delmar Blvd. St. Louis, DeBaliviere Place, St. Louis, MO
Space Type
Retail
1 space

1,420 SF
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$12.00/SF/YR
Loughborough Plaza Shopping Center
4344 Loughborough Avenue St. Louis, Boulevard Heights, St. Louis, MO
Space Type
Retail
2 spaces

1,950 - 2,200 SF
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$12.00/SF/YR
Hampton Avenue Retail
3511-3525 Hampton Avenue, Lindenwood Park, St. Louis, MO
Space Type
Retail
1 space

3,000 SF
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Call Broker for Details
900 Block of S 4th St.
900-916 S 4th Street, Downtown Saint Louis, Saint Louis, MO
Property Type
Office
Built in 1899

22,000 SF
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$17.50/SF/YR
Peabody Plaza
701 Market Street, Downtown Saint Louis, St. Louis, MO
Space Type
Office
11 spaces

2,076 - 30,191 SF
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$3.50/SF/YR
900 Hodiamont Avenue
900 Hodiamont Ave, West End Saint Louis, Saint Louis, MO
Space Type
Industrial
1 space

24,000 SF
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$10.00 - $18.00/SF/YR
Premiere Mixed-Use Property On The Hill
4916 Shaw Ave, The Hill, St. Louis, MO
Space Type
Office, Industrial
2 spaces

1,200 - 3,000 SF
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Price on request
Southside Tower
3611 S Grand Blvd, Tower Grove South, City Of Saint Louis, MO
Space Type
Retail
1 space

1,534 SF
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$18.00 - $19.00/SF/YR
St. Louis Place
200 N. Broadway, Downtown Saint Louis, St. Louis, MO
Space Type
Office
13 spaces

1,403 - 26,648 SF
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$600,000
The Marquette Building Condos
300-314 N Broadway, Downtown Saint Louis, St. Louis, MO
Property Type
Mixed Use
Built in 1917

37,558 SF
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$18.00/SF/YR
Turnkey Café/Restaurant Opportunity – 3137 Olive
3137 Olive Street St. Louis, Midtown Saint Louis, St. Louis, MO
Space Type
Retail
1 space

1,350 SF
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Price on request
Gateway Tower
1 Memorial Dr., Downtown Saint Louis, St. Louis, MO
Space Type
Office
12 spaces

915 - 50,460 SF
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Price on request
Mercantile Trust Building
721 Locust St., Downtown Saint Louis, St. Louis, MO
Property Type
Office
Built in 1902

122,181 SF
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$1.50 - $2.75/SF/YR
5661 Natural Bridge Avenue
5661 Natural Bridge Avenue, Mark Twain - I-70 Industrial, St. Louis, MO
Space Type
Industrial
1 space

40,000 SF
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$28.50/SF/YR
Highlands Plaza One
1001 Highlands Plaza Drive West, Cheltenham, St. Louis, MO
Space Type
Office
4 spaces

3,367 - 29,681 SF
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Price on request
Lafayette Square First Floor Office Suite
1808 Chouteau Ave., Lafayette Square, St. Louis, MO
Space Type
Office
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5 of 5
Price on request
Farmers Merchant
3550 S Grand Blvd, Gravois Park, Saint Louis, MO
Space Type
Retail
3 spaces

870 - 3,166 SF
1 of 1
Price on request
City Plaza
3431 Union Blvd., Wells Goodfellow, St. Louis, MO
Space Type
Retail
1 space

4,067 SF
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$3,500.00/MO
415 DeBaliviere Ave.
415 DeBaliviere Ave., Skinker DeBaliviere, St. Louis, MO
Space Type
Retail
1 space

2,980 SF

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Saint Louis, MO Commercial Real Estate Market Overview: Key Trends & Insights

Saint Louis has 8.5 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Saint Louis commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Saint Louis, MO

Based on the latest estimates, Saint Louis, MO offers almost 300 commercial listings for lease, totaling about 8.5 million square feet.

Current leasing options comprise 86 office listings, which represent approximately 44.33% out of the total leasing inventory. There are also 30 industrial and warehouse listings, making up 15.46% of the total. Additionally, 78 retail listings make up 40.21% of the local leasing market. These types are supplemented by 29 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 86 8,826,023 N/A

Retail 78 2,575,330 $14.26

Industrial 30 4,516,157 $6.67

Other 29 3,060,885 N/A

Commercial Real Estate for Sale in Saint Louis, MO

As of 2026, Saint Louis, MO has a total of 152 commercial real estate properties for sale.

This inventory includes 27 office assets, 32 industrial facilities and 25 retail properties available for purchase.

The largest share is held by Industrial, with 21.05% out of local properties for sale belonging to this asset type. Office has the next largest share at 17.76%, while Retail makes up 16.45% of commercial properties for sale in Saint Louis.

Property type No. of Listings Total Sq. Ft.

Office 27 8,826,023

Retail 25 2,575,330

Industrial 32 4,516,157

Other 68 8,802,183

Leading Commercial Real Estate Submarkets by Property Type in Saint Louis, MO

The leading commercial real estate submarkets for different property types in Saint Louis are:

Office: Downtown Saint Louis with 222 office listings, totaling 2,888,845 square feet.
Industrial: North Riverfront with 7 industrial listings, totaling 212,393 square feet.
Retail: Downtown Saint Louis with 29 retail listings, totaling 44,481 square feet.