Clayton, St. Louis County, MO Office Space

Search office properties for lease and view the Market Overview section below for local stats and insight.

174 Listings

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From $379/month

Regus
Regus - Clayton - Sevens Building
7777 Bonhomme Ave Suite 1800, Clayton, MO
Space Type
Private Offices
Space for 1 to 15 people
1 of 4

2 of 4

3 of 4

4 of 4
$21.00/SF/YR
7710-7730 Carondelet Avenue
7730 Carondelet Avenue, Clayton, St. Louis, MO
Space Type
Office
9 spaces

532 - 9,434 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
From $550/month

ThriveCo LLC
ThriveCo LLC - ThriveCo Clayton
222 S. Meramec Ave, Suite 202, Clayton, MO
Space Type
Private Offices
Space for 1 to 2 people
1 of 10

2 of 10

3 of 10

4 of 10

5 of 10

6 of 10

7 of 10

8 of 10

9 of 10

10 of 10
$20.00/SF/YR
Prominent Clayton Commercial Building
444 S Brentwood Blvd, Clayton, MO
Space Type
Office
1 space

15,518 SF
Narrow down your search by listing type
1 of 4

2 of 4

3 of 4

4 of 4
$32.00/SF/YR
8000 Maryland
8000 Maryland Ave., Clayton, MO
Space Type
Office
21 spaces

840 - 15,000 SF
1 of 3

2 of 3

3 of 3
$35.00/SF/YR
Regions Centre
8182 Maryland Avenue, Clayton, St. Louis, MO
Space Type
Office
1 space

20,296 SF
1 of 3

2 of 3

3 of 3
$35.00/SF/YR
8235 Forsyth Blvd
8235 Forsyth Blvd, Clayton, St. Louis, MO
Space Type
Office
1 space

7,976 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
$23.00/SF/YR
10 North Hanley Road
10 North Hanley Road, Clayton, MO
Space Type
Office
2 spaces

8,219 - 18,181 SF
1 of 14

2 of 14

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From $60/hour
$486/day

Office Evolution
Clayton Office Evolution
231 South Bemiston Avenue Suite 800, St. Louis, MO
Space Type
Meeting Rooms
Space for 4 to 18 people
1 of 4

2 of 4

3 of 4

4 of 4
$30.00/SF/YR
The Bank of America Building
7800 Forsyth Blvd, Clayton, MO
Space Type
Office
2 spaces

1,227 - 4,882 SF
1 of 4

2 of 4

3 of 4

4 of 4
$31.00/SF/YR
PNC Center
120 South Central Avenue, Clayton, St. Louis, MO
Space Type
Office
10 spaces

2,687 - 14,515 SF
1 of 4

2 of 4

3 of 4

4 of 4
$29.00/SF/YR
Old Town - 168 North Meramec Avenue
168 North Meramec Avenue, Clayton, St. Louis, MO
Space Type
Office
2 spaces

2,272 - 10,007 SF
1 of 4

2 of 4

3 of 4

4 of 4
$20.00/SF/YR
7818 Bonhomme Avenue
7818 Bonhomme Avenue, Clayton, St. Louis, MO
Space Type
Office
2 spaces

3,448 - 12,375 SF
1 of 4

2 of 4

3 of 4

4 of 4
$34.00 - $36.00/SF/YR
The Moneta Building
100 South Brentwood Blvd, Clayton, St. Louis, MO
Space Type
Office
2 spaces

9,541 - 14,183 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
$25.00/SF/YR
8151 Clayton Road
8151 Clayton Road, Clayton, MO
Space Type
Office
4 spaces

1,520 - 4,262 SF
1 of 3

2 of 3

3 of 3
$26.50/SF/YR
7711 Bonhomme Avenue
7711 Bonhomme Avenue, Clayton, St. Louis, MO
Space Type
Office
11 spaces

564 - 9,142 SF
1 of 1
Price on request
7801 Clayton Rd
7801 Clayton Rd, Clayton, Saint Louis, MO
Space Type
Office
1 space

1,658 SF
1 of 3

2 of 3

3 of 3
$29.00/SF/YR
Old Town - 150 North Meramec Avenue
150 North Meramec Avenue, Clayton, St. Louis, MO
Space Type
Office
1 space

1,737 SF
1 of 3

2 of 3

3 of 3
$24.50 - $32.00/SF/YR
Sevens Building
7777 Bonhomme Ave., Clayton, MO
Space Type
Office
14 spaces

746 - 11,693 SF
1 of 3

2 of 3

3 of 3
$27.50/SF/YR
The 222 Building
222 South Central Avenue, Clayton, St. Louis, MO
Space Type
Office
8 spaces

1,100 - 6,095 SF
1 of 4

2 of 4

3 of 4

4 of 4
Price on request
The 130 Building
130 South Bemiston Avenue, Clayton, St. Louis, MO
Space Type
Office
9 spaces

939 - 5,175 SF
1 of 3

2 of 3

3 of 3
Price on request
Bemiston Tower
231 South Bemiston Avenue, Clayton, St. Louis, MO
Space Type
Office
7 spaces

1,624 - 10,468 SF
1 of 3

2 of 3

3 of 3
$45.00/SF/YR
Centene Plaza Building B
7700 Forsyth Blvd., Clayton, MO
Space Type
Office
2 spaces

1,641 - 3,312 SF
1 of 7

2 of 7

3 of 7

4 of 7

5 of 7

6 of 7

7 of 7
From $589/month

Serendipity Labs
Serendipity Labs - St Louis Clayton
8112 Maryland Avenue, Suite 400, Clayton, MO
Space Type
Private Offices
Space for 1 to 5 people
1 of 6

2 of 6

3 of 6

4 of 6

5 of 6

6 of 6
$21.50/SF/YR
Parkway Tower
225-235 S Meramec Ave, Clayton, MO
Space Type
Office
34 spaces

252 - 5,908 SF
1 of 5

2 of 5

3 of 5

4 of 5

5 of 5
$33.50/SF/YR
Hanley Corporate Tower
101 South Hanley Road, Clayton, St. Louis, MO
Space Type
Office
9 spaces

1,861 - 20,019 SF
1 of 3

2 of 3

3 of 3
$43.50/SF/YR
The Plaza in Clayton
190 Carondelet Plaza, Clayton, St. Louis, MO
Space Type
Office
9 spaces

6,403 - 27,277 SF
1 of 4

2 of 4

3 of 4

4 of 4
$39.50/SF/YR
Commerce Tower
8001 Forsyth Blvd., Clayton, MO
Space Type
Office
1 space

5,897 SF
1 of 14

2 of 14

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8 of 14

9 of 14

10 of 14

11 of 14

12 of 14

13 of 14

14 of 14
From $469/month

Regus
Regus - St Louis - Clayton Pierre Laclede
7733 Forsyth Boulevard 11th Floor, Clayton, MO
Space Type
Private Offices
Space for 1 to 15 people
1 of 3

2 of 3

3 of 3
$29.00/SF/YR
Old Town - 165 North Meramec Avenue
165 North Meramec Avenue, Clayton, St. Louis, MO
Space Type
Office
1 space

3,052 SF
1 of 3

2 of 3

3 of 3
$29.00/SF/YR
Pierre Laclede Center I
7701 Forsyth Blvd, Clayton, St. Louis, MO
Space Type
Office
1 space

7,637 SF
1 of 6

2 of 6

3 of 6

4 of 6

5 of 6

6 of 6
$45.00/SF/YR
Centene Plaza Building C
7676 Forsyth Blvd., Clayton, MO
Space Type
Office
1 space

20,000 SF
1 of 2

2 of 2
Price on request

Alchemy
168 North Meramec Avenue
168 North Meramec Avenue #150, Clayton, MO
Space Type
Private Offices
$35.00/SF/YR
8182 Maryland Ave
8182 Maryland Ave Clayton Missouri 63105, Clayton, MO
Space Type
Office
1 space

20,296 SF
$35.00/SF/YR
8250 Forsyth Blvd
8250 Forsyth Blvd, Clayton, St. Louis, MO
Space Type
Office
1 space

1,210 SF
$20.00/SF/YR
212 & 214 South Central Ave
212 & 214 South Central Ave, Clayton, St Louis, MO
Space Type
Office
2 spaces

3,448 - 12,375 SF

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Average Rent for Office Space in Clayton, MO

Rents for offices in Clayton range between $23 and $35 per square foot, with the market-wide average currently at $30.25 per square foot according to the latest listing data.

Learn More About Office Spaces for Rent in Clayton, MO

The Clayton, MO market currently features 174 distinct office spaces available for lease, totaling approximately 1.0 million square feet.

Local inventory includes subtypes such as General Office with 135 listings, as well as other property types such as Creative.

Available office spaces range from 252 square feet to 27,666 square feet, with an average size of 5,759 square feet, accommodating businesses across various growth stages and operational requirements.

Range Total Square Feet Share of Total Office

25k to 50k Sq. Ft. 296,940 3.84%

50k to 100k Sq. Ft. 1,030,927 13.34%

100k to 500k Sq. Ft. 5,781,089 74.81%

500k to 1M Sq. Ft. 618,331 8%

Of the office inventory in Clayton, 7 properties were constructed since 2000, typically offering up-to-date amenities. An additional 21 buildings were developed between 1975 and 2000, while the remaining 26 date prior to 1975.

Clayton, MO Office Property By Year Built

26

1950 - 1975

21

1975 - 2000

7

After 2000

Clayton, MO Office Market Breakdown

The office market in Clayton, MO comprises 31 buildings totaling 7.7 million square feet.

Class A and A+ properties make up 49.41% of the office market in Clayton, while Class B properties total 50.59% of the market.

Range Total Square Feet Share of Total Office

Class A 5,145,047 66.58%

Class B 2,475,164 32.03%

Class C 107,076 1.39%

The market offers substantial flexibility in space configuration, with spaces reaching up to 27,666 square feet and an average square footage of 5,759 across all spaces located here.