O'Fallon, MO Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

106 Listings

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$1,350,000
3446 Pheasant Meadow Dr
3446 Pheasant Meadow Dr, O Fallon, MO
Property Type
Restaurant
Built in 2003

4,688 SF
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$8.00/SF/YR
79 Hubble Drive
79 Hubble Drive, Dardenne Prairie, O'Fallon, MO
Space Type
Industrial
4 spaces

3,840 - 19,200 SF
1 of 1
Price on request
Reduced Price! ±14,000 SF Office Building on 2.42 AC
507 S Cool Springs Rd, O'Fallon, MO
Space Type
Mixed Use
1 space

14,000 SF
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$23.00/SF/YR
1 Progress Point Parkway
1 Progress Point Parkway, O'Fallon, MO
Space Type
Office
1 space

26,482 SF
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Price on request
Progress West Medical Campus - 856 Waterbury Falls Drive
856 Waterbury Falls Drive, O'Fallon, MO
Space Type
Office
2 spaces

2,218 - 3,107 SF
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$5.25/SF/YR
831 Lone Star Drive
831 Lone Star Drive, O'Fallon, MO
Space Type
Industrial
1 space

102,135 SF
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$33.00/SF/YR
Winghaven Medical Office Plaza
5551 Winghaven Boulevard, Winghaven Country Club, O'Fallon, MO
Space Type
Mixed Use
1 space

1,075 SF
1 of 1
Price on request
1.95-Acre Pad Site Available For Development
3019 Winghaven Blvd, Winghaven Country Club, O'Fallon, MO
Space Type
Mixed Use
1 space

84,942 SF
1 of 1
Price on request
12,000 SF Stand-Alone Industrial Building For Lease
1510 Progress W Ln, O'Fallon, MO
Space Type
Industrial
1 space

12,000 SF
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$30.00/SF/YR
7429 State Route N
7429 State Route N, Dardenne Prairie, MO
Space Type
Retail
1 space

1,579 SF
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$4,400,000
102-212 Crafton Drive
102-212 Crafton Drive, O'Fallon, MO
Property Type
Industrial
4,750 SF
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$16.00/SF/YR
1153 Bryan Rd
1153 Bryan Rd, O'Fallon, MO
Space Type
Retail
2 spaces

3,511 SF
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$16.00 - $18.00/SF/YR
Woodlawn Plaza
8610-8648 Mexico Road O’fallon, O'Fallon, MO
Space Type
Retail
3 spaces

1,400 - 5,250 SF
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Price on request

80 Twenty Studios
80 Twenty Studios
2528 State Highway K, O'Fallon, MO
Space Type
Private Offices
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2 of 2
Price on request

LifeWorks
LifeWorks - Business Center
1001 Boardwalk Springs Place #111, O'Fallon, MO
Space Type
Private Offices
$1,050,000
Hwy K & Crusher Dr
Hwy K & Crusher Dr, O'Fallon, MO
Property Type
VacantLand
2.41 Acre
$1,382,594
Hawk Ridge Trail & Highway N - Lot 3
Hawk Ridge Trail, Winghaven Country Club, Lake Saint Louis, MO
Property Type
VacantLand
1.38 Acre
$18.00/SF/YR
Hillmann Farm Plaza
1240 Bryan Road, O'Fallon, MO
Space Type
Retail
2 spaces

1,300 - 1,304 SF
Price on request
610 N Main St
608 N Main St, O'Fallon, MO
Space Type
Retail
2 spaces

1,480 SF
$1,907,492
Laboure Outlots - Lot D
4721 Hwy K, O'Fallon, MO
Property Type
VacantLand
65,776 SF
Price on request
Hwy 364 & Hwy K
Hwy 364 & Hwy K, O'Fallon, MO
Space Type
Land
1 space

1,089,000 SF
$288,585
1048 Cool Springs Industrial Drive
1048 Cool Springs Industrial Dr, O'Fallon, MO
Property Type
Other
Price on request
2601 State Highway K
2601 State Highway K, O'Fallon, MO
Space Type
Retail
1 space

38,685 SF
$28.00/SF/YR
O'Fallon Center
1224 Highway K, O'Fallon, MO
Space Type
Retail
1 space

3,612 SF
Price on request
29-39 O'Fallon Square
29-39 O'Fallon Square, O'Fallon, MO
Space Type
Retail
1 space

1,200 SF
$3.84 - $22.80/SF/YR
Peruque Crossing
1061 Peruque Crossing Court, O'Fallon, MO
Space Type
Office
2 spaces

2,185 - 2,700 SF
Price on request
Hwy. K & O’Fallon Road Lot 3
3701 Hwy K, O'Fallon, MO
Property Type
VacantLand
1.78 Acre
$2,139,667
Hawk Ridge Trail & Highway N - Lot 5
Hawk Ridge Trail, Winghaven Country Club, Lake Saint Louis, MO
Property Type
VacantLand
3.07 Acre
Price on request
3500 Hwy. K - Lot 2
3500 Hwy. K, O'Fallon, MO
Property Type
VacantLand
1.75 Acre
Price on request
1400 Grant Industrial Drive
1400 Grant Industrial Dr, O'Fallon, MO
Property Type
Industrial
Built in 2024

21,000 SF
Price on request
3500 Hwy. K - Lot 3
3500 Hwy. K, O'Fallon, MO
Property Type
VacantLand
$1,382,594
Hawk Ridge Trail & Highway N - Lot 2
Hawk Ridge Trail, Winghaven Country Club, Lake Saint Louis, MO
Property Type
VacantLand
1.38 Acre
$475,000
Lakeside Shoppes
3002 - 4002 Winghaven Boulevard, Winghaven Country Club, O'Fallon, MO
Property Type
VacantLand
1.09 Acre
$7.50/SF
West Terra Lane
West Terra Lane & Genteman Road, O'Fallon, MO
Property Type
VacantLand
8.47 Acre
$500,000
4249 Keaton Crossing Blvd
4249 Keaton Crossing Blvd, O Fallon, MO
Property Type
VacantLand
0.94 Acre
Price on request
4551 State Highway K
4551 State Highway K, O'Fallon, MO
Space Type
Retail
1 space

7,930 SF
$2,500,000
Waterbury Falls Drive, Lot 4
Waterbury Falls Drive, O'Fallon, MO
Property Type
VacantLand
3.79 Acre
Price on request
The Streets of Caledonia
Highway DD and I-64, Winghaven Country Club, O'Fallon, MO
Space Type
Land
11 spaces

41,817.6 - 1,932,321.6 SF
Price on request
Hwy. K & O’Fallon Road Lot 1
3701 Hwy. K, O'Fallon, MO
Property Type
VacantLand
Price on request
Bryan Rd. & Feise Rd.
Bryan Rd. & Feise Rd., Dardenne Prairie, MO
Property Type
VacantLand

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O'Fallon, MO Commercial Real Estate Market Overview: Key Trends & Insights

O'Fallon has 6.2 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 100 properties.

This overview provides a snapshot of the O'Fallon commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in O'Fallon, MO

Based on the latest estimates, O'Fallon, MO offers almost 100 commercial listings for lease, totaling about 6.2 million square feet.

Current leasing options comprise 7 office listings, which represent approximately 19.44% out of the total leasing inventory. There are also 4 industrial and warehouse listings, making up 11.11% of the total. Additionally, 25 retail listings make up 69.44% of the local leasing market. These types are supplemented by 14 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 7 200,517 N/A

Retail 25 512,077 $15.81

Industrial 4 164,557 N/A

Other 14 5,825,979 N/A

Commercial Real Estate for Sale in O'Fallon, MO

As of 2026, O'Fallon, MO has a total of 47 commercial real estate properties for sale.

This inventory includes 2 office assets, 3 industrial facilities and 2 retail properties available for purchase.

The largest share is held by Industrial, with 6.38% out of local properties for sale belonging to this asset type. Office has the next largest share at 4.26%, while Retail makes up 4.26% of commercial properties for sale in O'Fallon.

Property type No. of Listings Total Sq. Ft.

Office 2 200,517

Retail 2 512,077

Industrial 3 164,557

Other 40 10,942,983