Monroe County, FL Commercial Real Estate - 82 Listings
Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.
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7070 Overseas Hwy, Roosevelt Point, MARATHON, FLProperty Type- Other
For Sale- $1,450,000
Built in 1954 / Property size 4,168 SF -
101350 Overseas Highway, Key Largo Trailer Village, Key Largo, FLProperty Type
- Other
For Sale- $3,500,000
Built in 2016 / Property size 5,177 SF -
718-720 Caroline Street, Historic Seaport, Key West, FLProperty Type- Retail
For Sale- $2,095,000
Built in 1918 / Property size 3,424 SF -
1421 First Street, New Town Key West, Key West, FLProperty Type- Office
For Sale- $1,250,000
Property size 1,393 SF -

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9141 Overseas Highway, Gulfstream Shore, Marathon, FLSpace Type- Office
For Lease- $850.00/MO
1 space available / 83 SF -
22814 Overseas Hwy, Cudjoe Key, Cudjoe, FLProperty Type- Other
For Sale- $925,000
Built in 1976 / Property size 1,120 SF -
323 Overseas Hwy, Big Coppitt Key, Key West, FLProperty Type- Other
For Sale- $3,600,000
Built in 2020 / Property size 6,912 SF -
6950 Overseas Hwy, Roosevelt Point, MARATHON, FLProperty Type- Other
For Sale- $2,200,000
Built in 1984 / Property size 2,762 SF -
30582 5th Ave, Big Pine Key, FLProperty Type- VacantLand
For Sale- $895,000
Built in 1976 / Property size 2,192 SF -
951 Caroline St, Historic Seaport, Key West, FLSpace Type- Office
For Lease- $3,600.00/MO
1 space available / 1,200 SF -
5701 Overseas Hwy, Sombrero Beach, MARATHON, FLProperty Type- Other
For Sale- $275,000
Built in 1979 / Property size 947 SF -
3140 Northside Dr # F, New Town Key West, Key West, FLProperty Type- Office
For Sale- $1,200,000
Built in 1991 / Property size 2,045 SF -
1215 Duval St, Upper Duval, Key West, FLProperty Type- Other
For Sale- $3,675,000
Built in 1953 / Property size 2,244 SF -
38 Coco Plum Drive, Coco Plum, Marathon, FLProperty Type- Unassigned
For Sale- $4,950,000
Built in 1994 / Property size 5,439 SF -
68200 Overseas Hwy, Layton, LAYTON, FLProperty Type- Other
For Sale- $415,000
Built in 1978 / Property size 800 SF -
81900 Overseas Hwy, Stratton's, Islamorada, FLProperty Type- Retail
For Sale- $2,950,000
Built in 1975 / Property size 5,232 SF -
1111 12th Street, New Town Key West, Key West, FLSpace Type- Office
For Lease- $26,276.25/MO
1 space available / 7,007 SF -
74560 Overseas Hwy, Port Antigua, ISLAMORADA, FLProperty Type- Other
For Sale- $3,349,000
Built in 1983 / Property size 6,071 SF -
418 Eaton Street, Historic Seaport, Key West, FLSpace Type- Retail
For Lease- $4,450.00/MO
1 space available / 971 SF -
30330 Overseas Hwy, Big Pine Key, Big Pine, FLProperty Type- Other
For Sale- $3,100,000
Built in 1979 / Property size 5,250 SF -
421 - 423 Simonton Street, Historic Seaport, Key West, FLProperty Type- Other
For Sale- $5,850,000
Built in 2020 / Property size 3,010 SF -
532 Margaret Street, Old Town Key West, Key West, FLProperty Type- Other
For Sale- $2,950,000
Built in 1958 / Property size 2,490 SF -
823 Fleming Street, Historic Seaport, Key West, FLProperty Type- Other
For Sale- $19,550,000
Built in 1892 / Property size 14,161 SF -
218 Whitehead St, Truman Annex, Key West, FLProperty Type- Retail
For Sale- $4,400,000
Built in 1942 / Property size 7,755 SF -
607 Fleming St, Historic Seaport, Key West, FLSpace Type- Retail
For Lease- $4,656.00 - $4,750.00/MO
2 spaces available / 805 - 1,496 SF -
30200 Overseas Highway, Big Pine Key, FLProperty Type- Unassigned
For Sale- $999,000
Built in 1970 / Property size 3,200 SF -
431 Front Street, Historic Seaport, Key West, FLSpace Type- Retail
For Lease- $5,300.00 - $5,828.00/MO
2 spaces available / 326 - 657 SF -
1 Kyle Way S, Knights Key Village, Marathon, FLProperty Type
- Multi-Family
For Sale- $1,450,000
Built in 2026 / Property size 44,100 SF -
3706 North Roosevelt Boulevard #208, Key West, FL
RP Business Center - 3706 North Roosevelt Blvd
RP Business CenterSpace Type- Private Offices
For Lease-
From $950/month
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91200 Overseas Hwy, Camp Pleasant, Tavernier, FL
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0 Overseas Hwy, Camp Pleasant, Tavernier, FLProperty Type
- Retail
For Sale- $10,000,000
Built in 1958 / Property size 2,922 SF -
6495 Overseas Hwy, Puerta Del Sol, Marathon, FLSpace Type
- Land
For Lease- $175,000.00/YR
1 space available / 44,866.8 SF -
6011 Peninsular Ave, Stock Island, Key West, FL
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802 White Street, Old Town Key West, Key West, FLSpace Type
- Office
For Lease- $3,250.00/MO
1 space available / 994 SF -
89015 Overseas Hwy, Indian Waterways, Islamorada, FLProperty Type
- Industrial
For Sale- $149,000
Property size 1,948 SF -
86701 Overseas Hwy, Treasure Harbor, Islamorada, FLSpace Type
- Retail
For Lease- $2.00 - $2.50/SF/YR
1 space available / 1,000 SF -
Overseas Highway, Teatable Key, Islamorada, FLProperty Type
- Retail
For Sale- $10,000,000
Built in 1980 / Property size 5,421 SF -
1301 SW 2nd Ave, Mandalay, Key Largo, FL
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103400 Overseas Hwy, Cross Key Waterway Estates, Key Largo, FL
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218 Whitehead St, Truman Annex, Key West, FLSpace Type
- Mixed Use
For Lease- $2,750.00 - $5,500.00/MO
3 spaces available / 501 - 1,407 SF
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