Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

331 Listings

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$35.00/SF/YR
113 Orange Street
113 Orange St, Central Park, Durham, NC
Space Type
Retail
1 space

3,514 SF
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$26.50/SF/YR
Meridian Corporate Center - 2645 Meridian Pkwy
2645 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
6 spaces

2,166 - 5,597 SF
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Price on request
TBC | 4020
4020 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
1 space

9,566 SF
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$25.00 - $850.00/SF/YR
1904 Front St
1904 Front St, Croasdaile, Durham, NC
Space Type
Office
4 spaces

144 - 1,706 SF
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From $559/month

Spaces
Spaces - Durham - Mangum Street
555 South Mangum Street #100, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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2550 Durham-Chapel Hill Blvd
2550 Durham-Chapel Hill Blvd, Tuscaloosa - Lakewood, Durham, NC
Space Type
Land
1 space

78,408 SF
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From $359/month

Regus
Regus - Durham - Shannon Road
3511 Shannon Road 3rd Floor, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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Price on request
Westgate Office Center
3518 Westgate Dr, Chapel Hill Road, Durham, NC
Space Type
Office
3 spaces

2,895 - 15,530 SF
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Price on request
The Roxboro at Venable Center
380 East Pettigrew Street, Downtown Durham, Durham, NC
Space Type
Office
13 spaces

3,497 - 28,956 SF
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$25.00/SF/YR
3400 Croasdaile Dr
3400 Croasdaile Dr, Croasdaile, Durham, NC
Space Type
Office
1 space

3,574 SF
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Price on request
1011 Riddle Road
1011 Riddle Road, North Carolina Central University, Durham, NC
Space Type
Land
1 space

103,672 SF
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One City Center
101 Corcoran Street, Downtown Durham, Durham, NC
Space Type
Office
3 spaces

5,717 - 31,321 SF
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Roger's Alley
200 North Mangum Street, Downtown Durham, Durham, NC
Space Type
Retail
2 spaces

3,238 - 3,244 SF
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Price on request
2510 Meridian
2510 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
4 spaces

2,997 - 21,226 SF
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$19.00/SF/YR
Roxboro Road Professional Center
4210 N. Roxboro Street, Suite 140, Summer Meadow, Durham, NC
Space Type
Office
1 space

2,408 SF
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$1,600,000
1004 NC 54 Hwy E
1004 NC 54 Hwy E, Parkwood, Durham, NC
Property Type
VacantLand
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121 Hunt St.
121 Hunt St., Old North Durham, Durham, NC
Space Type
Mixed Use
1 space

23,657 SF
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$29.50/SF/YR
1000 W Main
1000 W Main St, Trinity Park, Durham, NC
Space Type
Office
1 space

4,100 SF
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$989,000
SW Durham Redevelopment Opportunity
1426 E. NC-54 Hwy, Parkwood, Durham, NC
Property Type
VacantLand
1,440 SF
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$14.00 - $22.00/SF/YR
Highgate Center
5316 Highgate Drive, Darby Glen, Durham, NC
Space Type
Office
11 spaces

800 - 1,528 SF
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Price on request
2520 Meridian
2520 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
7 spaces

5,638 - 23,335 SF
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$28.50/SF/YR
Park City
2222 NC 54, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

4,509 - 19,792 SF
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$22.00 - $31.11/SF/YR
Herald-Sun Building
2828 Pickett Road, Cameron Woods, Durham, NC
Space Type
Office
10 spaces

135 - 3,241 SF
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Price on request
Hope Valley Pointe
4810 Hope Valley Road, Suite 107, Valley Brook, Durham, NC
Space Type
Retail
1 space

2,653 SF
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Price on request
600 Frontier
600 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

1,033 - 3,559 SF
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2 of 2
From $700/month

Alexander Business Suites
Alexander Business Suites - Research Triangle Park
68 TW Alexander Drive, Durham, NC
Space Type
Private Offices
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2 of 2
Price on request

Recity
Recity - Network
112 Broadway Street #B, Durham, NC
Space Type
Private Offices
Space for 1 to 4 people
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2 of 2
Price on request

BioLabs
BioLabs - 701 West Main Street
701 West Main Street, Durham, NC
Space Type
Private Offices
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2 of 2
From $550/month

Orenge
Orenge - 3211 Shannon Road
3211 Shannon Road, Durham, NC
Space Type
Private Offices
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2 of 2
Price on request

American Underground
American Underground - Durham
201 West Main Street #100, Durham, NC
Space Type
Private Offices
Space for 1 to 25 people
Price on request
Brightleaf Square
905 West Main Street, Downtown Durham, Durham, NC
Space Type
Office, Retail
19 spaces

918 - 6,880 SF
Price on request
2714 South Miami Boulevard
2714 South Miami Boulevard, Taylor Estates, Durham, NC
Property Type
Industrial
Built in 1972

21,700 SF
Price on request
One Park Center
4018 Patriot Drive, Research Triangle Park, Durham, NC
Space Type
Industrial
1 space

14,420 SF
Price on request
5 Laboratory Drive - 14,259 SF lab & office for sublease
5 Laboratory Dr, Research Triangle Park, NC 27709, NC
Space Type
Office
1 space

14,259 SF
Price on request
Warehouse/Flex Showroom Available for Sublease
3140 Hillsborough Rd, Watts Hospital - Hillandale, Durham, NC
Space Type
Industrial
1 space

27,550 SF
1 of 1
Price on request
Duke Children's
3116 Duke Street, Stadium Heights, Durham, NC
Space Type
Office
Price on request
Regional Commerce Center - Building 5
857 South Briggs Avenue, North Carolina Central University, Durham, NC
Space Type
Industrial
1 space

56,000 SF
Price on request
Marketplace at Ellis Crossing Lot 10
NEC Ellis Rd & Watchorn St, Wynterfield, Durham, NC
Property Type
VacantLand
3.39 Acre
Price on request
Shops at Northgate
1620 Guess Rd, West Murray - Broad, Durham, NC
Space Type
Retail
6 spaces

1,034 - 7,800 SF
Price on request
Prologis Liberty Ridge
1953 TW Alexander Drive, Suite A, Stirrup Creek, Durham, NC
Space Type
Industrial
1 space

84,000 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 137 office listings, which represent approximately 57.56% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.49% of the total. Additionally, 57 retail listings make up 23.95% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 137 12,839,171 $33.69

Retail 57 4,565,886 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,067,864 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,839,171

Retail 7 4,565,886

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 151 office listings, totaling 2,339,980 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.