Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

343 Listings

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$4,600,000
602 N Mangum Street
602 N Mangum Street, Cleveland - Holloway, Durham, NC
Property Type
VacantLand
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Hope Valley Pointe
4810 Hope Valley Road, Suite 107, Valley Brook, Durham, NC
Space Type
Retail
1 space

2,653 SF
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Contact Broker
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Property Type
Industrial
Built in 1984

341,298 SF
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$27.50/SF/YR
Imperial Center - Cambridge Hall & Canterbury Hall
4815 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
6 spaces

1,747 - 15,769 SF
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Hock Plaza II
600 Douglas Street, Crest Street, Durham, NC
Space Type
Office
2 spaces

28,800 SF
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$3,000.00/SF/MO
5001 Pleasant Green Road #UT
5001 Pleasant Green Rd # Ut, Willow Ridge, Durham, NC
Space Type
Land
1 space

54,450 SF
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1212 Broad Street, Suite B
1212 Broad Street, Suite B, Walltown, Durham, NC
Space Type
Office
1 space

1,356 SF
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Central Park One
5001 S Miami Blvd, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

3,464 - 13,205 SF
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$989,000
SW Durham Redevelopment Opportunity
1426 E. NC-54 Hwy, Parkwood, Durham, NC
Property Type
VacantLand
1,440 SF
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$25.00/SF/YR
3400 Croasdaile Dr
3400 Croasdaile Dr, Croasdaile, Durham, NC
Space Type
Office
1 space

3,574 SF
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$13.60/SF/YR
RTP Industrial Flex Warehouse Distribution
2456 South Miami Boulevard, Taylor Estates, Durham, NC
Space Type
Industrial
1 space

32,000 SF
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433 W. Main Street
433 W. Main Street, Warehouse District, Durham, NC
Space Type
Office
2 spaces

2,376 - 5,676 SF
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$1,800,000
216-218 Rigsbee Avenue
216-218 Rigsbee Avenue, Central Park, Durham, NC
Property Type
Office
Built in 1936

10,461 SF
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$36.00/SF/YR
108 Morris Street
108 Morris Street, Central Park, Durham, NC
Space Type
Retail
1 space

1,606 SF
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Atlas
321 W Corporation St, Old North Durham, Durham, NC
Space Type
Retail
2 spaces

418 - 1,313 SF
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Meridian Corporate Center - 2700 Meridian Pkwy
2700 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

7,274 - 25,952 SF
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$6,500.00/MO
1707 Midland Terrace
1707 Midland Terrace, Colonial Village, Durham, NC
Space Type
Industrial
1 space

8,124 SF
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Price on request
351,030 SF Class A Industrial Facility for Lease
1716 Camden Ave, Colonial Village, Durham, NC
Space Type
Industrial
1 space

351,030 SF
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Price on request
3105 Colclough Avenue
3105 Colclough Avenue, Crown Point, Durham, NC
Property Type
Other
12.83 Acre
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5213 South Alston Avenue
5213 South Alston Avenue, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

41,998 - 42,000 SF
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$29.50/SF/YR
1000 W Main
1000 W Main St, Trinity Park, Durham, NC
Space Type
Office
1 space

4,100 SF
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$27.50/SF/YR
Imperial Center - Oxford Place
1005 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
7 spaces

1,476 - 5,099 SF
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Miami North Office Park
4426 South Miami Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,641 - 18,380 SF
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TBC Place II
4025 Stirrup Creek Drive, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

10,843 - 23,790 SF
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Price on request
105 W. Morgan Street
105 W. Morgan Street, Central Park, Durham, NC
Space Type
Retail
4 spaces

971 - 3,307 SF
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Price on request
100 Meredith Dr
100 Meredith Dr, Parkwood, Durham, NC
Space Type
Office
1 space

430 SF
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$960,000 or $11 PSF
Imperial Center Retail/Daycare/Hotel Site/Office
Slater Road at Parliament Court , Research Triangle Park, Durham, NC
Property Type
VacantLand
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400 Frontier
400 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

488 - 7,916 SF
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$28.00/SF/YR
2605 Meridian
2605 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
3 spaces

3,927 - 39,613 SF
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One City Center
101 Corcoran Street, Downtown Durham, Durham, NC
Space Type
Office
3 spaces

5,717 - 31,321 SF
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Greenwood Commons
5410 NC-55 Hwy, Parkwood, Durham, NC
Space Type
Retail
2 spaces

1,550 - 1,820 SF
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$28.00/SF/YR
Kitt Creek Commons
5125 NC-55 Hwy, Unit 103, Parkwood, Durham, NC
Space Type
Retail
1 space

1,168 SF
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$19.00 - $23.00/SF/YR
Westgate II Office Park
3622 Lyckan Pkwy, Chapel Hill Road, Durham, NC
Space Type
Office
4 spaces

303 - 750 SF
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$23.11/SF/YR
3821 Durham Chapel Hill Blvd
3821 Durham Chapel Hill Blvd, Chapel Hill Road, Durham, NC
Space Type
Industrial
1 space

18,176 SF
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Price on request
SouthPoint Crossing
202 NC Hwy 54, Folkestone, Durham, NC
Space Type
Retail
3 spaces

1,400 - 4,060 SF
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$1,350,000
1001, 1003 & 1005 Broad Street
1001, 1003 & 1005 Broad Street, Old West Durham, Durham, NC
Property Type
VacantLand
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$22.00 - $31.11/SF/YR
Herald-Sun Building
2828 Pickett Road, Cameron Woods, Durham, NC
Space Type
Office
10 spaces

135 - 3,241 SF
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RTI International Campus - Cox & Hobbs Buildings
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

5,304 - 15,781 SF
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Price on request

BioLabs
701 West Main Street
701 West Main Street, Durham, NC
Space Type
Private Offices
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From $700/month

Alexander Business Suites
Alexander Business Suites - Research Triangle Park
68 TW Alexander Drive, Durham, NC
Space Type
Private Offices

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.7 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.7 million square feet.

Current leasing options comprise 143 office listings, which represent approximately 58.13% out of the total leasing inventory. There are also 47 industrial and warehouse listings, making up 19.11% of the total. Additionally, 56 retail listings make up 22.76% of the local leasing market. These types are supplemented by 16 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 143 13,457,693 $33.69

Retail 56 4,349,055 $27.31

Industrial 47 5,119,397 $11.91

Other 16 974,507 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 62 commercial real estate properties for sale.

This inventory includes 14 office assets, 8 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 22.58% out of local properties for sale belonging to this asset type. Industrial has the next largest share at 12.90%, while Retail makes up 11.29% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 14 13,457,693

Retail 7 4,349,055

Industrial 8 5,119,397

Other 33 11,462,574

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 168 office listings, totaling 2,693,678 square feet.
Industrial: Research Triangle Park with 10 industrial listings, totaling 929,753 square feet.
Retail: Downtown Durham with 19 retail listings, totaling 48,021 square feet.