Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

328 Listings

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Price on request
The Tower at Mutual Plaza
411 West Chapel Hill Street, Downtown Durham, Durham, NC
Space Type
Office, Retail
7 spaces

1,489 - 14,357 SF
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Meridian Corporate Center - 2700 Meridian Pkwy
2700 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

7,274 - 25,952 SF
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Durham Summit
3414 Duke Street, Stadium Heights, Durham, NC
Space Type
Office
1 space

6,029 SF
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505 S Duke St
505 S Duke St, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

2,501 - 4,897 SF
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1 of 1
Price on request
Parkside 70
1020 S Miami Blvd, Pleasant Drive, Durham, NC
Property Type
Flex Space
Built in 1990

35,020 SF
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Diamond View III
359 Blackwell St, Downtown Durham, Durham, NC
Space Type
Office
4 spaces

27,259 - 97,611 SF
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Price on request
129,600 SF Industrial Building for Lease
1218 Stone Park Ct, Wynterfield, Durham, NC
Space Type
Industrial
1 space

129,600 SF
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Imperial Tower
4820 Emperor Boulevard, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

10,025 - 30,827 SF
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$2,650,745
5412 S Miami Blvd
5412 S Miami Blvd, Research Triangle Park, Durham, NC
Property Type
Retail
Built in 2004

6,534 SF
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From $459/month

HQ
HQ - Imperial Raleigh
4819 Emperor Blvd., Imperial Business Park Suite 400, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
1 of 1
Price on request
2520 Meridian
2520 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
5 spaces

1,520 - 9,096 SF
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$25.00/SF/YR
5234 North Roxboro Street
5234 North Roxboro Street, River Forest, Durham, NC
Space Type
Retail
1 space

1,000 SF
1 of 1
Price on request
2700 Meridian
2700 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
1 space

25,952 SF
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$27.50/SF/YR
Imperial Center - Chelsea Place
1007 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,494 - 20,588 SF
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Price on request
5213 South Alston Avenue
5213 South Alston Avenue, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

41,998 - 42,000 SF
1 of 1
Price on request
2525 Meridian
2525 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
14 spaces

12,882 SF
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$20.00/SF/YR
2919 Colony Road
2919 Colony Road, Colony Park, Durham, NC
Space Type
Office
1 space

3,867 SF
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$29.50/SF/YR
YORKSHIRE PLACE
4307 Emperor Boulevard, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

1,601 - 27,822 SF
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From $459/month

Regus
Regus - Durham - RTP Meridian
2530 Meridian Parkway Suite 300, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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$850,000
1715 Holloway St
1715 Holloway St, Wellons Village, Durham, NC
Property Type
Retail
Built in 1973

4,500 SF
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Price on request
SouthCourt Building
3211 Shannon Road, Valley Run, Durham, NC
Space Type
Office, Retail
11 spaces

1,007 - 19,351 SF
1 of 1
Price on request
2510 Meridian
2510 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
4 spaces

2,997 - 21,226 SF
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$28.50/SF/YR
Quadrangle III
6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
8 spaces

1,929 - 15,037 SF
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Royal at Imperial Center
4222 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
1 space

11,303 SF
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$989,000
SW Durham Redevelopment Opportunity
1426 E. NC-54 Hwy, Parkwood, Durham, NC
Property Type
VacantLand
1,440 SF
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Price on request

American Underground
American Underground - Durham
201 West Main Street #100, Durham, NC
Space Type
Private Offices
Space for 1 to 25 people
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2 of 2
Price on request

Recity
Recity - Network
112 Broadway Street #B, Durham, NC
Space Type
Private Offices
Space for 1 to 4 people
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2 of 2
From $550/month

Orenge
Orenge - 3211 Shannon Road
3211 Shannon Road, Durham, NC
Space Type
Private Offices
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2 of 2
From $700/month

Alexander Business Suites
Alexander Business Suites - Research Triangle Park
68 TW Alexander Drive, Durham, NC
Space Type
Private Offices
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2 of 2
Price on request

BioLabs
BioLabs - 701 West Main Street
701 West Main Street, Durham, NC
Space Type
Private Offices
Price on request
Research Tri-Center North IV
2710 Weck Drive, Taylor Estates, Durham, NC
Space Type
Industrial
1 space

108,750 SF
Price on request
Office Site E at Hub RTP
4170 Sancar Way, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

30,000 SF
$695,000
830 N Mangum St
830 N Mangum St, Old Five Points, Durham, NC
Property Type
Office
3,173 SF
$5,500.00/MO
2202 East Geer Street
2202 E Geer St, Gorman, Durham, NC
Space Type
Industrial
1 space

40,075.2 SF
Price on request
Research Tri-Center South II
2511 South Tricenter Blvd, Research Triangle Park, Durham, NC
Space Type
Industrial
1 space

31,243 SF
Price on request

First Flight
First Flight - Venture Center
2 Davis Drive, Durham, NC
Space Type
Desks
Price on request
Durham Gateway
4902 Leesville Rd, Ravenstone, Durham, NC
Space Type
Industrial
1 space

182,176 SF
Price on request
Marketplace at Ellis Crossing Lot 10
NEC Ellis Rd & Watchorn St, Wynterfield, Durham, NC
Property Type
VacantLand
3.39 Acre
Price on request
Homestead Market
105 West State Highway 54, Darby Glen, Durham, NC
Space Type
Retail
2 spaces

1,440 - 45,495 SF
$20.00/SF/YR
MIDWAY
921 Midway Avenue, Pleasant Drive, Durham, NC
Space Type
Retail
1 space

1,435 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 139 office listings, which represent approximately 57.92% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.33% of the total. Additionally, 57 retail listings make up 23.75% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 139 12,703,431 $33.69

Retail 57 4,647,213 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,056,974 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,703,431

Retail 7 4,647,213

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 159 office listings, totaling 2,387,279 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.