Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

329 Listings

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Price on request
RTI International Campus - Hill Building
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

30,808 - 32,745 SF
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Price on request
Welcome Venture Park - Building E
Welcome Venture Park - Building E, Glennstone, Durham, NC
Space Type
Industrial
1 space

23,000 SF
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1212 Broad Street, Suite B
1212 Broad Street, Suite B, Walltown, Durham, NC
Space Type
Office
1 space

1,356 SF
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$25.00/SF/YR
3400 Croasdaile Dr
3400 Croasdaile Dr, Croasdaile, Durham, NC
Space Type
Office
1 space

3,574 SF
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129,600 SF Industrial Building for Lease
1218 Stone Park Ct, Wynterfield, Durham, NC
Space Type
Industrial
1 space

129,600 SF
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$17.00 - $21.00/SF/YR
Hamilton Centre
1415 West State Highway 54, The Landing at Southpoint, Durham, NC
Space Type
Office
3 spaces

983 - 2,074 SF
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$16.00 - $21.00/SF/YR
New Haven Center
2310 South Miami Blvd, Taylor Estates, Durham, NC
Space Type
Office
7 spaces

1,002 - 1,870 SF
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$30.50/SF/YR
Winchester Place
4309 Emperor Blvd. , Research Triangle Park, Durham, NC
Space Type
Office
6 spaces

3,111 - 20,208 SF
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From $49/hour
$397/day

Venture X
Venture X Durham - RTP
600 Park Offices Drive, Durham, NC
Space Type
Meeting Rooms
Space for 4 to 14 people
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Garrett Road Assemblage
5314 Garrett Rd, 4200 & 4211 Old Chapel Hill Rd, 4309 Jean Ave, Bent Creek - Woodberry Forest, Durham, NC
Space Type
Land
1 space

66,211 SF
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$850,000
1715 Holloway St
1715 Holloway St, Wellons Village, Durham, NC
Property Type
Retail
Built in 1973

4,500 SF
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Price on request
Quadrangle IV
6340 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
2 spaces

5,366 - 19,925 SF
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121 Hunt St.
121 Hunt St., Old North Durham, Durham, NC
Space Type
Mixed Use
1 space

23,657 SF
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Price on request
Newcastle North
1035 Swabia Court, Research Triangle Park, Durham, NC
Space Type
Office
1 space

15,127 SF
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From $459/month

HQ
HQ - Imperial Raleigh
4819 Emperor Blvd., Imperial Business Park Suite 400, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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Price on request
Old Chapel Hill Road Assemblage
4138 & 4142 Old Chapel Hill Road, Westgate Townes, Durham, NC
Space Type
Land
1 space

77,101 SF
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Price on request
4430 Hillsborough Rd
4430 Hillsborough Rd, West Hills, Durham, NC
Space Type
Mixed Use
1 space

6,552 SF
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Price on request
RTI International Campus - Cox & Hobbs Buildings
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

5,304 - 15,781 SF
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Price on request
800 Frontier
800 Park Offices Dr, Research Triangle Park, Morrisville, NC
Space Type
Office
3 spaces

4,006 - 4,390 SF
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$36.00/SF/YR
108 Morris Street
108 Morris Street, Central Park, Durham, NC
Space Type
Retail
1 space

1,606 SF
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$2,200,000
2000, 2008 & 2014 Cheek Road
2000, 2008 & 2014 Cheek Road, Merrick Moore, Durham, NC
Property Type
VacantLand
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Price on request
700 Frontier
700 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
1 space

19,537 SF
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One City Center
101 Corcoran Street, Downtown Durham, Durham, NC
Space Type
Office
3 spaces

5,717 - 31,321 SF
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Price on request
Miami North Office Park
4426 South Miami Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,641 - 18,380 SF
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Price on request

American Underground
American Underground - Durham
201 West Main Street #100, Durham, NC
Space Type
Private Offices
Space for 1 to 25 people
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2 of 2
Price on request

BioLabs
BioLabs - 701 West Main Street
701 West Main Street, Durham, NC
Space Type
Private Offices
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2 of 2
From $700/month

Alexander Business Suites
Alexander Business Suites - Research Triangle Park
68 TW Alexander Drive, Durham, NC
Space Type
Private Offices
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2 of 2
From $550/month

Orenge
Orenge - 3211 Shannon Road
3211 Shannon Road, Durham, NC
Space Type
Private Offices
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2 of 2
Price on request

Recity
Recity - Network
112 Broadway Street #B, Durham, NC
Space Type
Private Offices
Space for 1 to 4 people
Price on request
5211 Summer Rose Ln
5211 Summer Rose Ln, Ravenstone, Durham, NC
Property Type
VacantLand
35.02 Acre
Price on request
Durham Gateway
5112 Leesville Rd, Ravenstone, Durham, NC
Space Type
Industrial
1 space

275,935 SF
Price on request
South Square
4120 University Dr, Chapel Hill Road, Durham, NC
Space Type
Retail
2 spaces

2,100 - 4,651 SF
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Price on request
Duke Children's
3116 Duke Street, Stadium Heights, Durham, NC
Space Type
Office
Price on request
Regional Commerce Center - Building 5
857 South Briggs Avenue, North Carolina Central University, Durham, NC
Space Type
Industrial
1 space

56,000 SF
Price on request
2714 South Miami Boulevard
2714 South Miami Boulevard, Taylor Estates, Durham, NC
Property Type
Industrial
Built in 1972

21,700 SF
Price on request
3300 North Duke Street
3300 North Duke Street, Stadium Heights, Durham, NC
Property Type
VacantLand
2.14 Acre
$22.00 - $23.00/SF/YR
5107 Southpark Dr
5107 Southpark Dr, Darby Glen, Durham, NC
Space Type
Office
2 spaces

490 - 1,657 SF
Price on request
Durham Gateway
4816 Leesville Rd, Ravenstone, Durham, NC
Space Type
Industrial
1 space

40,618 SF
Price on request

Alexandria LaunchLabs
Alexandria LaunchLabs - Alexandria Center for Advanced Technologies
Research Triangle Park #220, Durham, NC
Space Type
Private Offices
$422,000/SF
411 Andrews Rd
411 Andrews Rd, American Village, Durham, NC
Property Type
Office
2,080 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 137 office listings, which represent approximately 57.56% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.49% of the total. Additionally, 57 retail listings make up 23.95% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 137 12,839,171 $33.69

Retail 57 4,565,886 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,067,864 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,839,171

Retail 7 4,565,886

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 151 office listings, totaling 2,339,980 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.