Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

337 Listings

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$19.50 - $27.14/SF/YR
200 Meredith Drive
200 Meredith Drive, Parkwood, Durham, NC
Space Type
Office
3 spaces

597 - 1,628 SF
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Price on request
3105 Colclough Avenue
3105 Colclough Avenue, Crown Point, Durham, NC
Property Type
Other
12.83 Acre
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$28.50/SF/YR
Imperial Center - Stratford Hall
1009 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,800 - 18,993 SF
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From $359/month

Regus
NC, Durham - Shannon Road
3511 Shannon Road 3rd Floor, Durham, NC
Space Type
Private Offices
Space for 1 to 50 people
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$27.50/SF/YR
Imperial Center - Chelsea Place
1007 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,494 - 20,588 SF
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Price on request
Industrial Warehouse in West Durham
121 S. LaSalle Street, Old West Durham, Durham, NC
Space Type
Industrial
1 space

24,000 SF
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$14.00 - $27.00/SF/YR
1515 North Pointe Drive
1515 North Pointe Drive, Duke Homestead, Durham, NC
Space Type
Retail
2 spaces

2,247 - 7,300 SF
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$3,000.00/SF/MO
5001 Pleasant Green Road #UT
5001 Pleasant Green Rd # Ut, Willow Ridge, Durham, NC
Space Type
Land
1 space

54,450 SF
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$1,750,000
2322 So-Hi Drive
2322 So-Hi Drive, Research Triangle Park, Durham, NC
Property Type
VacantLand
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Price on request
RTI International Campus - Hill Building
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

30,808 - 32,745 SF
1 of 1
$22.00/SF/YR
201 E. Main Street
201 E. Main Street, Downtown Durham, Durham, NC
Space Type
Retail
1 space

3,057 SF
1 of 1
Price on request
2500 Meridian
2500 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
1 of 1
Price on request
2520 Meridian
2520 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
5 spaces

1,520 - 9,096 SF
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Price on request
Greenwood Commons
5410 NC-55 Hwy, Parkwood, Durham, NC
Space Type
Retail
2 spaces

1,550 - 1,820 SF
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$375,000
2404 Dearborn Drive
2404 Dearborn Drive, Crown Point, Durham, NC
Property Type
VacantLand
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$19.00 - $23.00/SF/YR
Westgate II Office Park
3622 Lyckan Pkwy, Chapel Hill Road, Durham, NC
Space Type
Office
4 spaces

303 - 750 SF
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$34.00/SF/YR
Imperial Tobacco Building
215 Morris Street, Warehouse District, Durham, NC
Space Type
Office
1 space

18,502 SF
1 of 1
Price on request
2605 Meridian
2605 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
3 spaces

2,772 - 39,613 SF
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Price on request
The Roxboro at Venable Center
380 East Pettigrew Street, Downtown Durham, Durham, NC
Space Type
Office
13 spaces

3,497 - 28,956 SF
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Price on request
505 S Duke St
505 S Duke St, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

2,501 - 4,897 SF
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$1,385,000
1015 Ellis Road
1015 Ellis Road, Wynterfield, Durham, NC
Property Type
Industrial
4,940 SF
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Price on request
3200 SF Retail/Office | Base Rent from $17/SF + NNN
1912 E NC 54 Hwy, Parkwood, Durham, NC
Space Type
Mixed Use
1 space

3,200 SF
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$24.50/SF/YR
Park Forty Plaza
1000 Park Forty Plaza, Parkwood, Durham, NC
Space Type
Office
13 spaces

1,411 - 26,309 SF
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Contact Broker
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Property Type
Industrial
Built in 1984

341,298 SF
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Price on request
Quadrangle V
6330 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
3 spaces

7,957 - 20,508 SF
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Price on request
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Space Type
Industrial
3 spaces

36,378 - 96,386 SF
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Price on request
400 Frontier
400 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

488 - 7,916 SF
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Price on request
The Imperial Center - Nottingham Hall
4505 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
6 spaces

1,224 - 28,079 SF
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$4,500.00/MO
5112 Neal Rd
5112 Neal Road, Bennet Place, Durham, NC
Space Type
Office
1 space

3,000 SF
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Price on request
Trust Building
212 West Main Street, Central Park, Durham, NC
Space Type
Office
5 spaces

999 - 7,642 SF
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$23.00/SF/YR
4321 Medical Park Dr
4321 Medical Park Dr, Summer Meadow, Durham, NC
Space Type
Office
3 spaces

4,257 - 10,056 SF
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$5,225,000
1426 & 1500 S. Miami Blvd, 1408 Marly Drive
1426 & 1500 S. Miami Blvd, 1408 Marly Drive, Pleasant Drive, Durham, NC
Property Type
Retail
22,998 SF
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$7.50 - $8.00/SF/YR
1500 E Club Blvd
1500 E Club Blvd, Crown Point, Durham, NC
Space Type
Industrial
1 space

31,710 SF
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From $459/month

HQ
Imperial Raleigh
4819 Emperor Blvd., Imperial Business Park Suite 400, Durham, NC
Space Type
Private Offices
Space for 1 to 50 people
1 of 1
$20.00/SF/YR
3825 S Roxboro St
3825 S Roxboro St, Stratford Lakes, Durham, NC
Space Type
Retail
5 spaces

1,600 - 1,840 SF
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$17.00 - $21.00/SF/YR
Hamilton Centre
1415 West State Highway 54, The Landing at Southpoint, Durham, NC
Space Type
Office
3 spaces

983 - 2,074 SF
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$450,000
4348 S. Alston Avenue
4348 S. Alston Avenue, Research Triangle Park, Durham, NC
Property Type
VacantLand
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$989,000
SW Durham Redevelopment Opportunity
1426 E. NC-54 Hwy, Parkwood, Durham, NC
Property Type
VacantLand
1,440 SF
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Price on request
Meridian Corporate Center - 2505 Meridian Pkwy
2505 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

4,604 - 6,450 SF
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$28.50/SF/YR
Quadrangle III
6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
8 spaces

1,929 - 15,037 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 12.0 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 12.0 million square feet.

Current leasing options comprise 139 office listings, which represent approximately 58.16% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.41% of the total. Additionally, 56 retail listings make up 23.43% of the local leasing market. These types are supplemented by 19 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 139 13,034,738 $33.69

Retail 56 4,514,055 $27.31

Industrial 44 4,959,155 $12.21

Other 19 1,128,258 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 11 office assets, 8 industrial facilities and 6 retail properties available for purchase.

The largest share is held by Office, with 18.97% out of local properties for sale belonging to this asset type. Industrial has the next largest share at 13.79%, while Retail makes up 10.34% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 11 13,034,738

Retail 6 4,514,055

Industrial 8 4,959,155

Other 33 11,842,017

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 160 office listings, totaling 2,529,624 square feet.
Industrial: Research Triangle Park with 10 industrial listings, totaling 918,141 square feet.
Retail: Downtown Durham with 17 retail listings, totaling 45,116 square feet.