Durham, NC Office Space

Search office properties for lease and view the Market Overview section below for local stats and insight.

457 Listings

Price on request

Locale321
Locale321 - 321 East Chapel Hill Street
321 East Chapel Hill Street, Durham, NC
Space Type
Private Offices
Space for 1 to 6 people
From $25/hour

Triangle Meeting & Studio Space
Triangle Meeting & Studio Space - 2603 South Miami Boulevard
2603 South Miami Boulevard, Durham, NC
Space Type
Meeting Rooms
Space for 1 to 75 people
Price on request
Triangle Biotechnology Center
323 Foster St, Central Park, Durham, NC
Space Type
Office
1 space

18,525 SF
From $450/month

Frontier RTP
800 Park Offices Drive
800 Park Offices Drive 1st floor, Durham, NC
Space Type
Private Offices
Space for 1 to 150 people
Narrow down your search by listing type
Price on request
Oakrige
4852 Durham-Chapel Hill Blvd, Garret Farms - Porchlight - Hartley, Durham, NC
Space Type
Office
2 spaces

12,600 SF
Price on request

Alexandria LaunchLabs
Alexandria LaunchLabs - Alexandria Center for Advanced Technologies
Research Triangle Park #220, Durham, NC
Space Type
Private Offices
Price on request

Mint Coworking
Mint Coworking - 500 West Morgan Street
500 West Morgan Street, Durham, NC
Space Type
Private Offices
1 of 26

2 of 26

3 of 26

4 of 26

5 of 26

6 of 26

7 of 26

8 of 26

9 of 26

10 of 26

11 of 26

12 of 26

13 of 26

14 of 26

15 of 26

16 of 26

17 of 26

18 of 26

19 of 26

20 of 26

21 of 26

22 of 26

23 of 26

24 of 26

25 of 26

26 of 26
Price on request
Quadrangle II, III, IV & V
6320-6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
1 of 1
Price on request
UNC Family Medicine
5704 Fayetteville Road, Folkestone, Durham, NC
Space Type
Office
Price on request

Alexandria LaunchLabs
Alexandria LaunchLabs - Alexandria Center for Agtech
9 Laboratory Drive #263, Durham, NC
Space Type
Private Offices
Price on request
One Park Center
4018 Patriot Drive, Research Triangle Park, Durham, NC
Space Type
Office
1 space

14,420 SF
Price on request

First Flight
First Flight - Venture Center
2 Davis Drive, Durham, NC
Space Type
Meeting Rooms
$30.00/SF/YR
West Village
700 W Main St, Warehouse District, Durham, NC
Space Type
Office
2 spaces

2,196 - 5,747 SF
$25.00/SF/YR
Kress Building
110 W Main St, Downtown Durham, Durham, NC
Space Type
Office
1 space

7,306 SF
Price on request

Durham Bottling Company
Durham Bottling Company - 506 Ramseur Street
506 Ramseur Street, Durham, NC
Space Type
Private Offices
$18.00 - $24.00/SF/YR
Bentley Ridge
5607 & 5611 NC 55, Audubon Park, Duham, NC
Space Type
Office
4 spaces

847 - 1,416 SF
$20.00/SF/YR
Brassfield IV
4528 Hillsborough Rd, West Hills, Durham, NC
Space Type
Office
1 space

750 SF
$22.00/SF/YR
4220 NC Hwy 55
4220 NC Hwy 55, Copper Creek, Durham, NC
Space Type
Office
1 space

2,860 SF
$22.00 - $23.00/SF/YR
5107 Southpark Dr
5107 Southpark Dr, Darby Glen, Durham, NC
Space Type
Office
2 spaces

490 - 1,657 SF
$18.00/SF/YR
411 Andrews Rd
411 Andrews Rd, American Village, Durham, NC
Space Type
Office
1 space

2,080 SF
Price on request
701 William Vickers Ave
701 William Vickers Ave, Downtown Durham, Durham, NC
Space Type
Office
1 space

4,806 SF
Price on request
Washington Building
324 Blackwell St, Downtown Durham, Durham, NC
Space Type
Office
1 space

4,541 SF
Price on request
One RTP Tower
4130 Sancar Way, Research Triangle Park, NC
Space Type
Office
9 spaces

30,000 SF
Price on request

North Carolina Biotechnology Center
North Carolina Biotechnology Center
15 TW Alexander Drive, Durham, NC
Space Type
Private Offices
Price on request
East of Broad
NC-55 & Old Powell Rd, Wynterfield, Durham, NC
Space Type
Office
1 space

40,000 SF
$21.00/SF/YR
3209 Guess Rd
3209 Guess Rd, Omah Street, Durham, NC
Space Type
Office
2 spaces

620 SF
Price on request
Brightleaf Square
905 West Main Street, Downtown Durham, Durham, NC
Space Type
Office
10 spaces

918 - 6,880 SF
Price on request
Peabody Place
112 S Duke St, Downtown Durham, Durham, NC
Space Type
Office
5 spaces

2,000 - 8,130 SF
1 of 1
Price on request
Duke Children's
3116 Duke Street, Stadium Heights, Durham, NC
Space Type
Office
Price on request
Durham Summit
3414 Duke Street, Stadium Heights, Durham, NC
Space Type
Office
1 space

6,029 SF
$16.00/SF/YR
Pine Ridge Office Centre
6015 & 6011 Fayetteville Rd, Crooked Creek, Durham, NC
Space Type
Office
1 space

800 SF
Price on request
3601 Hillsborough Rd
3601 Hillsborough Rd, Waterford, Durham, NC
Space Type
Office
1 space

22,286 SF
from $15.00

Switchyards
Switchyards - 733 Foster Street
733 Foster Street, Durham, NC
Space Type
Meeting Rooms
From $525/month

Orenge
Orenge - 119 Orange Street
119 Orange Street, Durham, NC
Space Type
Private Offices
$38.00/SF/YR
Cobb Building
614 W Main St, Warehouse District, Durham, NC
Space Type
Office
1 space

20,126 SF
$18.00/SF/YR
2810 Hillsborough Rd
2810 Hillsborough Rd, Old West Durham, Durham, NC
Space Type
Office
1 space

2,978 SF
$17.25 - $18.00/SF/YR
4324 S Alston Ave
4324 S Alston Ave, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

926 - 1,833 SF
Price on request

American Underground
American Underground - 324 Blackwell Street
324 Blackwell Street #900, Durham, NC
Space Type
Private Offices
$29.50/SF/YR
4000 Sancar Way
4000 Sancar Way, Research Triangle Park, Durham, NC
Space Type
Office
7 spaces

1,332 - 3,846 SF
Price on request
Office Site E at Hub RTP
4170 Sancar Way, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

30,000 SF

Other Popular Searches

Raleigh Office Space

242 listings
Greensboro Office Space

95 listings
Winston - Salem Office Space

83 listings
Cary Office Space

73 listings
Morrisville Office Space

62 listings
Chapel Hill Office Space

24 listings
Wake Forest Office Space

5 listings

Raleigh Commercial Real Estate

487 listings
Winston - Salem Commercial Real Estate

338 listings
Greensboro Commercial Real Estate

311 listings
Durham Commercial Real Estate

300 listings
Cary Commercial Real Estate

132 listings
Morrisville Commercial Real Estate

95 listings
Chapel Hill Commercial Real Estate

50 listings
Wake Forest Commercial Real Estate

39 listings
Hillsborough Commercial Real Estate

10 listings
Siler City Commercial Real Estate

7 listings

Creedmoor Commercial Real Estate

7 listings
Carrboro Commercial Real Estate

3 listings

Average Rent for Office Space in Durham, NC

Rents for offices in Durham range between $11 and $70.83 per square foot, with the market-wide average currently at $26.67 per square foot according to the latest listing data.

Learn More About Office Spaces for Rent in Durham, NC

The Durham, NC market currently features 457 distinct office spaces available for lease, totaling approximately 4.4 million square feet.

Local inventory includes subtypes such as General Office with 250 listings, as well as other property types such as Life Sciences and Creative Office.

Available office spaces range from 135 square feet to 260,000 square feet, with an average size of 9,914 square feet, accommodating businesses across various growth stages and operational requirements.

Range Total Square Feet Share of Total Office

25k to 50k Sq. Ft. 2,504,455 8.96%

50k to 100k Sq. Ft. 5,840,910 20.9%

100k to 500k Sq. Ft. 13,745,358 49.17%

500k to 1M Sq. Ft. 1,198,809 4.29%

> 1M Sq. Ft. 4,664,066 16.69%

Of the office inventory in Durham, 68 properties were constructed since 2000, typically offering up-to-date amenities. An additional 143 buildings were developed between 1975 and 2000, while the remaining 31 date prior to 1975.

Durham, NC Office Property By Year Built

1

Before 1900

10

1900 - 1925

6

1925 - 1950

14

1950 - 1975

143

1975 - 2000

68

After 2000

Durham, NC Office Market Breakdown

The office market in Durham, NC comprises 147 buildings totaling 28.0 million square feet.

Class A and A+ properties make up 56.23% of the office market in Durham, while Class B properties total 35.07% of the market and Class C properties take up the remaining 8.7%.

Range Total Square Feet Share of Total Office

Class A 14,473,755 51.78%

Class B 12,134,028 43.41%

Class C 1,345,815 4.81%

The market offers substantial flexibility in space configuration, with spaces reaching up to 260,000 square feet and an average square footage of 9,914 across all spaces located here.

Best Neighborhoods for Office Space in Durham, NC

Durham’s neighborhood with the most office spaces is Research Triangle Park, offering 151 listings currently available.

The neighborhoods with the next largest offerings include Copper Creek with 73 listings, as well as Downtown Durham, which offers a total of 57 listings.

Neighborhood No. of Listings Total Sq. Ft.

Research Triangle Park 151 2,339,980

Copper Creek 73 580,769

Downtown Durham 57 613,427

Central Park 23 204,876

The Landing at Southpoint 21 129,262