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For Lease

300 Massachusetts Avenue

300 Massachusetts Avenue, Cambridge, MA 02139

213,092

SF Available
Now fully permitted, 300 Mass Ave is moving into the construction phase, with completion and occupancy anticipated in early 2016. The research and office portions of the building – all but 15,000 square feet that has been designated for retail uses – will be occupied by Millennium/Takeda, a life science company that is currently in University Park at MIT and will be expanding its footprint to support a more extensive research program. Retail shops and restaurants will occupy nearly the entire frontage of the building along Massachusetts Avenue, and will be identified when construction of the project is further along.

Rental Details

  • Number of spaces 6
  • Total square feet available 213,092 SF
  • For Lease Contact for pricing
  • Space Types Unassigned
  • Lease Type NNN
  • Date Updated May 25, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

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For Lease 6 Spaces Available

Partial 1 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,517 SF
  • Floor 1
  • Divisible Space 35,517 - 35,517 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Partial 2 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,515 SF
  • Floor 2
  • Divisible Space 35,515 - 35,515 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Partial 3 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,515 SF
  • Floor 3
  • Divisible Space 35,515 - 35,515 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Partial 4 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,515 SF
  • Floor 4
  • Divisible Space 35,515 - 35,515 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Partial 5 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,515 SF
  • Floor 5
  • Divisible Space 35,515 - 35,515 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Partial 6 Floor

  • Space Type Unassigned
  • Lease Rate Negotiable
  • Total Space Available 35,515 SF
  • Floor 6
  • Divisible Space 35,515 - 35,515 SF
  • Available Date Jul 1, 2026
  • Lease Type NNN
  • Sublease Yes
  • Build Type Full build out
broker
Julia Ryan

Cushman & Wakefield

Contacts

broker
Julia Ryan

Cushman & Wakefield

Building Details

  • For Lease Contact for pricing
  • Property Type Unassigned
  • Property Size 245,937 SF
  • # of Floors 6
  • Parking Ratio 1.00 / 1,000 SF
  • Year Built 2016
  • Date Updated May 25, 2026

Getting Around

  • Walk Score ®

    Walker's Paradise (97)
  • Transit Score ®

    Good Transit (68)
  • Bike Score ®

    Biker's Paradise (99)
Powered by Walk Score ®

Location

  • City Cambridge, MA
  • Neighborhood Cambridgeport
  • Zip Code 02139
  • Market Boston
  • Map
  • Street

Points of Interest

Kendall/MIT

0.68 miles

Kenmore

0.93 miles

Lansdowne

1.02 miles

Union Square

1.06 miles

Hynes

1.13 miles

Saint Mary's Street

1.20 miles

Harvard Square

1.28 miles

Church Street - Johnston Gate

1.32 miles

Church Street - West

1.32 miles

Speedway

0.72 miles

Shell

0.80 miles

Magazine Beach Shell

0.87 miles

Mobil

1.09 miles

Tesla Supercharger

1.19 miles

Sunoco

1.20 miles

Tesla Destination Charger

1.32 miles

The Colonnade Hotel

1.47 miles

Gulf

1.60 miles

University Park at MIT Parking Garage

0.15 miles

158 Mass Ave Lot

0.19 miles

N10 Lot

0.22 miles

MIT Visitor Lot

0.25 miles

City Of Cambridge Parking Lot 5

0.26 miles

Green Street Garage

0.28 miles

N4 Albany Garage

0.34 miles

Ensemble Therapeutics

0.39 miles

MIT Main Lot

0.40 miles

Zipcar

0.76 miles

Somerville No Touch Car Wash

1.61 miles

Avis

1.61 miles

Prestige

1.71 miles

Somerville Car Wash

1.74 miles

Landbird

1.81 miles

Allston Car Wash

1.90 miles

Shield System Car Wash

1.99 miles

ScrubaDub Brookline

2.04 miles

Roxy’s Grilled Cheese

0.02 miles

Naco Taco

0.05 miles

Sydney's Grille

0.06 miles

Beantown Taqueria

0.10 miles

The Dial

0.10 miles

Cambridge Pizza

0.10 miles

Desi Dhaba

0.11 miles

Salts

0.11 miles

Shōjō Cambridge

0.13 miles

H Mart

0.27 miles

Cleenland

0.31 miles

Daily Table

0.37 miles

Whole Foods Market

0.44 miles

Tropical Dimension Food Store

0.77 miles

Brothers Marketplace

0.80 miles

Trader Joe's

0.82 miles

Broadway Market

1.08 miles

Marshalls

1.11 miles

Concilio Hispano

0.17 miles

CVS Pharmacy

0.31 miles

Cambridge Police Reporting Station

0.32 miles

Walgreens

0.32 miles

Mass General Brigham Urgent Care

0.36 miles

River Street Firehouse

0.57 miles

MIT Police Station

0.60 miles

Cambridge Police Department

0.75 miles

Boston Acne Specialists

0.77 miles

300 Massachusetts Avenue Listing Summary

  • What is the total size of 300 Massachusetts Avenue?

    300 Massachusetts Avenue has a total of 245,937 square feet.

  • What is the year built for 300 Massachusetts Avenue?

    The year built for 300 Massachusetts Avenue is 2016.

Contact Listing Broker
broker
Julia Ryan

Cushman & Wakefield

  1. 1Main information
  2. 2Extra information
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