For Lease

301 Broadway

301 Broadway St, Cape Girardeau, MO 63701

3,600

SF Available
Situated in the heart of downtown Cape Girardeau, 301 Broadway anchors one of the city’s most architecturally significant and walkable blocks. The property is surrounded by a strong mix of local restaurants, retail shops, and entertainment venues, creating consistent foot traffic throughout the day and evening. The building itself is a local landmark with over a century of history and was fully revitalized in 2005 as a modern mixed-use environment. It is home to the Southeast Missourian and other dynamic tenants, drawing daily visitors and reinforcing its role as a central hub of activity. Just steps from some of the region’s most popular dining and nightlife destinations—and positioned between St. Louis and Memphis—this location offers both local engagement and regional appeal. Ample nearby parking and multiple access points further enhance convenience for customers and employees alike.Position your business in one of downtown Cape Girardeau’s most iconic and high-visibility locations. This ±3,600 SF street-level space at 301 Broadway offers a rare opportunity to join a vibrant retail corridor, directly adjacent to Magnolia Bridal—one of the area’s premier destination boutiques. The space is currently configured as professional office space, providing an easy, cost-effective transition for office or service users, while offering a highly adaptable layout for retail conversion. With dual storefront entrances along Broadway, the space can be easily reimagined to create an inviting, customer-focused retail presence. Tenants will benefit from a full-service lease structure, sprinklered space, and access to shared restroom and breakroom facilities—with the option to build out private amenities if desired. Existing furniture is available, allowing for immediate occupancy and minimal upfront investment. Located within the historic Missourian Building, this space blends timeless architecture with modern functionality—ideal for retailers, boutiques, showrooms, or experiential concepts seeking a distinctive downtown presence.

Key features

  • ±3,600 SF street-level retail opportunity
  • Access to shared restroom & breakroom (or ability to add private facilities)
  • Ample nearby parking with multiple access points
  • Existing office buildout allows for quick occupancy
  • Flexible layout: retail, showroom, or office use
  • Full-service lease structure
  • Furniture available for immediate use
  • Located directly next to Magnolia Bridal (strong destination traffic driver)
  • Located in the historic Missourian Building – a true local landmark
  • Prime downtown Broadway frontage with excellent visibility
  • Sprinklered space
  • Surrounded by restaurants, retail, and entertainment
  • Two storefront entrances – ideal for retail conversion

Rental Details

  • Number of spaces 1
  • Total square feet available 3,600 SF
  • For Lease $26.00/SF/YR
  • Space Types Street Retail
  • Lease Type Full Service
  • Date Updated Apr 24, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

For Lease 1 Space Available

Contacts

Matt Huber

Lorimont Commercial Real Estate

Building Details

  • For Lease $26.00/SF/YR
  • Property Type Retail - Street Retail
  • Property Size 21,507 SF
  • Building Class A
  • Date Updated Apr 24, 2026

Attachments

Getting Around

  • Walk Score ®

    Very Walkable (76)

  • Bike Score ®

    Somewhat Bikeable (48)
Powered by Walk Score ®

Location

  • City Cape Girardeau, MO
  • Zip Code 63701

Points of Interest

Jackson

9.40 miles

Iron Moountain Junction

9.71 miles

Rhodes

3.01 miles

Mobil

3.42 miles

Rhodes Travel Center

5.07 miles

Church overflow parking

5.90 miles

ALDI

1.62 miles

Kmart

1.82 miles

Schnucks

1.82 miles

West Park Mall

2.78 miles

TJ Maxx

3.24 miles

Target

3.27 miles

Walmart Supercenter

3.58 miles

Kohl's

3.61 miles

Bob's Food Liner

6.28 miles

301 Broadway St Listing Summary

  • The Price for Retail Space at 301 Broadway St

    The cost of renting retail space in a property highly depends on features such as its location, parking availability and type of retail space, or advantages and features that might be unique to it. When it comes to 301 Broadway St, asking rent starts at $$26.00/SF/YR per square foot.

    Reach out to the listing broker for information on best parking and other access options at or near the property.

  • Retail Space Options Available at 301 Broadway St

    The property exclusively contains Street Retail space totaling 3,600 square feet. The leasing opportunity here is available under Full Service lease terms.

    In addition to retail space type, you will also need to consider the space size that you need for your business to operate at its best. You will find 1 retail space(s) ranging from 1,000 square feet to 10,000 square feet at 301 Broadway St, which can serve small or medium retail businesses that are planning to accommodate growth throughout the duration of their lease at this address. For more information or to schedule a tour of the property, reach out using the contact form on this page to get in touch with a broker.

Contact Listing Broker
Matt Huber

Lorimont Commercial Real Estate

  1. 1Main information
  2. 2Extra information
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