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  1. Office Space
  2. MO
  3. Cape Girardeau

301 Broadway St

For Lease 1,250 SF

301 Broadway St, Cape Girardeau, MO 63701

301 Broadway sits in the core of downtown Cape Girardeau, surrounded by a vibrant mix of local restaurants, boutiques, and entertainment venues. This walkable district provides an energetic setting that enhances both employee experience and client engagement. The Missourian Building is one of the city’s most recognizable landmarks, blending historic charm with modern office and retail users. Its central location ensures convenient access to daily amenities, while nearby parking options make commuting simple. Strategically located between St. Louis and Memphis, Cape Girardeau offers strong regional connectivity along with a growing business community—making it an ideal place for companies to establish or expand their presence.Position your business in a professional, character-rich environment with this well-appointed second-floor 1,250 sf office suite at 301 Broadway in downtown Cape Girardeau. Designed for flexibility and efficiency, this space is ideal for small teams, startups, or satellite offices seeking a polished presence without excess space. The suite features a welcoming reception area, one private office, and a large conference room that can easily function as a second private office if needed. A spacious open area provides additional flexibility for cubicles, collaborative workspace, or creative use—allowing tenants to tailor the layout to fit their operations. With both stair and elevator access, the suite offers convenient entry for employees and clients. Tenants also benefit from access to shared restroom facilities, helping maximize usable square footage within the suite. Located within the historic Missourian Building, this space combines timeless architecture with modern functionality—offering a unique and professional setting in the heart of downtown.

Key features

  • 1 private office + large conference room (or second office)
  • Access to shared restrooms
  • Adaptable layout to fit a variety of business needs
  • Ample parking
  • Efficient second-floor 1,250 sf office suite
  • Elevator and stair access
  • Ideal for small businesses, startups, or satellite offices
  • Located in the historic Missourian Building
  • Open workspace for cubicles or flexible use
  • Reception area for professional first impressions
  • Walkable to downtown restaurants, retail, and amenities

Rental Details

  • Number of spaces 1
  • Total square feet available 1,250 SF
  • For Lease $25.00/SF/YR
  • Space Type Office
  • Lease Type Full Service
  • Latest Update Apr 24, 2026
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1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
Suite 2B Office $25.00/SF/YR 1,250 SF - Full Service

Suite 2B

Space Type

Office

Lease Rate

$25.00/SF/YR

Additional Rent

Price on request

Total Space Available

1,250 SF

Divisible Space

1,250 - 1,250 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

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Suite 2B

Space Type
Office
Lease Rate
$25.00/SF/YR
Total Space
1,250 SF
Lease Type
Full Service
Space Type

Office

Lease Rate

$25.00/SF/YR

Additional Rent

Price on request

Total Space Available

1,250 SF

Divisible Space

1,250 - 1,250 SF

Available Date

Immediate

Lease Type

Full Service

Renewal Option

Yes

Sublease

No

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Contacts

broker
Matt Huber

Lorimont Commercial Real Estate

Building Details

  • For Lease $25.00/SF/YR
  • Property Type Office - General Office
  • Property Size 21,507 SF
  • Additional Rent Price on request
  • Building Class A
  • Date Updated Apr 24, 2026

Location

  • City Cape Girardeau, MO
  • Zip Code 63701
  • Map
  • Street
  • Walk score 76/100 Very Walkable
  • Bike score 48/100 Somewhat Bikeable
Powered by Walk Score ®

Points of Interest

Gordonville

9.11 miles

Jackson

9.40 miles

Iron Moountain Junction

9.71 miles

Kidd's gas station

1.75 miles

Rhodes

3.01 miles

Mobil

3.42 miles

Rhodes Travel Center

5.07 miles

Over the road truck parking

5.00 miles

Church overflow parking

5.90 miles

Ram's Car Wash

6.10 miles

Kenny's Flippin Burgers

0.10 miles

Port Cape Girardeau Restaurant and Lounge

0.19 miles

McDonald's

1.44 miles

Hardee's

1.57 miles

Arby's

1.64 miles

Fazoli's

1.72 miles

Long John Silver's

1.75 miles

Wendy's

1.76 miles

Watami Sushi & Hibachi Steakhouse

1.76 miles

Burger King

1.77 miles

Walmart Neighborhood Market

1.56 miles

ALDI

1.62 miles

Kmart

1.82 miles

Schnucks

1.82 miles

West Park Mall

2.78 miles

TJ Maxx

3.24 miles

Target

3.27 miles

Walmart Supercenter

3.58 miles

Kohl's

3.61 miles

Bob's Food Liner

6.28 miles

Cape Girardeau Police Department

0.38 miles

Southeast Hospital

1.16 miles

Walgreens

1.73 miles

Saint Francis Medical Center

2.75 miles

Southeast Behavioral Hospital

2.79 miles

MediCenter Pharmacy

3.01 miles

Cape Girardeau Station 4

3.30 miles

Autism Support Now

3.32 miles

Scott City Police Department

6.00 miles

Scott City Fire Department Station 1

6.00 miles

Listing Summary

  • Office Space Available at 301 Broadway St

    Office space currently available at 301 Broadway St adds up to a total of 1,250 square feet across 1 listing(s). The largest individual space listed offers 1,250 square feet. Property use types available for lease at this property include: office.

  • Learn More about 301 Broadway St

    The property incorporates a total of 1,250 square feet of space.

    Interested in researching more about this property? Access in-depth research on 301 Broadway St, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

Contact Matt Huber
broker
Matt Huber

Lorimont Commercial Real Estate

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