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  1. Office Space
  2. MO
  3. Cape Girardeau
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For Lease

301 Broadway St

301 Broadway St, Cape Girardeau, MO 63701

1,250

SF Available
301 Broadway sits in the core of downtown Cape Girardeau, surrounded by a vibrant mix of local restaurants, boutiques, and entertainment venues. This walkable district provides an energetic setting that enhances both employee experience and client engagement. The Missourian Building is one of the city’s most recognizable landmarks, blending historic charm with modern office and retail users. Its central location ensures convenient access to daily amenities, while nearby parking options make commuting simple. Strategically located between St. Louis and Memphis, Cape Girardeau offers strong regional connectivity along with a growing business community—making it an ideal place for companies to establish or expand their presence.Position your business in a professional, character-rich environment with this well-appointed second-floor 1,250 sf office suite at 301 Broadway in downtown Cape Girardeau. Designed for flexibility and efficiency, this space is ideal for small teams, startups, or satellite offices seeking a polished presence without excess space. The suite features a welcoming reception area, one private office, and a large conference room that can easily function as a second private office if needed. A spacious open area provides additional flexibility for cubicles, collaborative workspace, or creative use—allowing tenants to tailor the layout to fit their operations. With both stair and elevator access, the suite offers convenient entry for employees and clients. Tenants also benefit from access to shared restroom facilities, helping maximize usable square footage within the suite. Located within the historic Missourian Building, this space combines timeless architecture with modern functionality—offering a unique and professional setting in the heart of downtown.

Key features

  • 1 private office + large conference room (or second office)
  • Access to shared restrooms
  • Adaptable layout to fit a variety of business needs
  • Ample parking
  • Efficient second-floor 1,250 sf office suite
  • Elevator and stair access
  • Ideal for small businesses, startups, or satellite offices
  • Located in the historic Missourian Building
  • Open workspace for cubicles or flexible use
  • Reception area for professional first impressions
  • Walkable to downtown restaurants, retail, and amenities

Rental Details

  • Number of spaces 1
  • Total square feet available 1,250 SF
  • For Lease $25.00/SF/YR
  • Space Types Office
  • Lease Type Full Service
  • Date Updated Apr 24, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

Suite 2B

  • Space Type Office
  • Lease Rate $25.00/SF/YR
  • Total Space Available 1,250 SF
  • Photos
  • Divisible Space 1,250 - 1,250 SF
  • Available Date Immediate
  • Lease Type Full Service
  • Renewal Option Yes
  • Sublease No
broker
Matt Huber

Lorimont Commercial Real Estate

Contacts

broker
Matt Huber

Lorimont Commercial Real Estate

Building Details

  • For Lease $25.00/SF/YR
  • Property Type Office - General Office
  • Property Size 21,507 SF
  • Building Class A
  • Date Updated Apr 24, 2026

Attachments

  • Property Brochure 1 ()opens in new window

Getting Around

  • Walk Score ®

    Very Walkable (76)
  • Bike Score ®

    Somewhat Bikeable (48)
Powered by Walk Score ®

Location

  • City Cape Girardeau, MO
  • Zip Code 63701
  • Map
  • Street

Points of Interest

Jackson

9.40 miles

Iron Moountain Junction

9.71 miles

Rhodes

3.01 miles

Mobil

3.42 miles

Rhodes Travel Center

5.07 miles

Church overflow parking

5.90 miles

Port Cape Girardeau Restaurant and Lounge

0.19 miles

McDonald's

1.44 miles

Hardee's

1.57 miles

Arby's

1.64 miles

Fazoli's

1.72 miles

Long John Silver's

1.75 miles

Wendy's

1.76 miles

Watami Sushi & Hibachi Steakhouse

1.76 miles

Burger King

1.77 miles

ALDI

1.62 miles

Kmart

1.82 miles

Schnucks

1.82 miles

West Park Mall

2.78 miles

TJ Maxx

3.24 miles

Target

3.27 miles

Walmart Supercenter

3.58 miles

Kohl's

3.61 miles

Bob's Food Liner

6.28 miles

Southeast Hospital

1.16 miles

Walgreens

1.73 miles

Saint Francis Medical Center

2.75 miles

Southeast Behavioral Hospital

2.79 miles

MediCenter Pharmacy

3.01 miles

Cape Girardeau Station 4

3.30 miles

Autism Support Now

3.32 miles

Scott City Police Department

6.00 miles

Scott City Fire Department Station 1

6.00 miles

301 Broadway St Listing Summary

  • Office Space Available at 301 Broadway St

    Office space currently available at 301 Broadway St adds up to a total of 1,250 square feet across 1 listing(s). The largest individual space listed offers 1,250 square feet. Property use types available for lease at this property include: office.

  • Learn More about 301 Broadway St

    The property incorporates a total of 1,250 square feet of space.

    Interested in researching more about this property? Access in-depth research on 301 Broadway St, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

Contact Listing Broker
broker
Matt Huber

Lorimont Commercial Real Estate

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