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  1. Office Space
  2. MO
  3. Saint Louis

754 S 4th St

For Lease 2,802 SF

754 S 4th Street, St Louis, MO 63102

Experience the vibrant energy of downtown St. Louis at 754 S 4th St! This historical district is animated by an array of trendy restaurants and bars. Busch Stadium is nearby, along with the BPV, and is also located within the heart of the music quarter of STL. The property is within walking distance to the iconic Gateway Arch, offering stunning views of the Mississippi River. Home to a diverse mix of office, creative, and loft spaces, the area is an ideal investment opportunity for those seeking a dynamic urban hub. Residents and professionals alike can enjoy cultural attractions such as the National Blues Museum and the City Museum, creating an unmatched work-life balance in this thriving neighborhood.Introducing 754 S 4th Street, a premier commercial space available for lease in St. Louis, MO. This meticulously designed property offers a prime location, excellent visibility, and an elegant modern aesthetic. Boasting spacious open layouts, high ceilings, and abundant natural light, this versatile space is perfectly suited for retail, creative space, or restaurant use. With its convenient amenities and sophisticated charm, this property presents an unparalleled opportunity for businesses seeking to establish a commanding presence in the heart of St. Louis. Experience the epitome of contemporary commercial space at 754 S 4th Street.

Key features

  • 1st Floor Retail Space with Prime Visibility
  • Abundant natural light throughout the space
  • Build-to-Suit space means your space can be custom-designed
  • Convenient amenities for tenants and clients
  • High visibility for maximum exposure
  • Lease prime real estate with the opportunity for a design-build retail space in the heart of the St Louis Music Quarter.
  • Modern and elegant interior design
  • Prime location in St. Louis city center
  • Prime Location Near Busch Stadium and the Arch Grounds
  • Sophisticated charm and contemporary appeal
  • Spacious open layouts with high ceilings
  • Versatile for retail, office, or restaurant use

Rental Details

  • Number of spaces 3
  • Total square feet available 2,802 SF
  • For Lease $1,250.00 - $4,000.00/MO
  • Space Type Street Retail, General Office, Creative Office
  • Lease Type Modified Gross
  • Latest Update Aug 31, 2026
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3 Spaces Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
First Floor Street Retail $4,000.00/MO 1,213 SF 1 Modified Gross

First Floor

Space Type

Street Retail

Lease Rate

$4,000.00/MO

Additional Rent

Price on request

Total Space Available

1,213 SF

Floor

1

Divisible Space

1,213 - 1,213 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Second Floor General Office $2,500.00/MO 1,213 SF 2 Modified Gross

Second Floor

Space Type

General Office

Lease Rate

$2,500.00/MO

Additional Rent

Price on request

Total Space Available

1,213 SF

Floor

2

Divisible Space

1,213 - 1,213 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Third Floor Creative Office $1,250.00/MO 376 SF 3 Modified Gross

Third Floor

Space Type

Creative Office

Lease Rate

$1,250.00/MO

Additional Rent

Price on request

Total Space Available

376 SF

Floor

3

Divisible Space

376 - 376 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

First Floor

Space Type
Street Retail
Lease Rate
$4,000.00/MO
Total Space
1,213 SF
Floor
1
Lease Type
Modified Gross
Space Type

Street Retail

Lease Rate

$4,000.00/MO

Additional Rent

Price on request

Total Space Available

1,213 SF

Floor

1

Divisible Space

1,213 - 1,213 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Second Floor

Space Type
General Office
Lease Rate
$2,500.00/MO
Total Space
1,213 SF
Floor
2
Lease Type
Modified Gross
Space Type

General Office

Lease Rate

$2,500.00/MO

Additional Rent

Price on request

Total Space Available

1,213 SF

Floor

2

Divisible Space

1,213 - 1,213 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Third Floor

Space Type
Creative Office
Lease Rate
$1,250.00/MO
Total Space
376 SF
Floor
3
Lease Type
Modified Gross
Space Type

Creative Office

Lease Rate

$1,250.00/MO

Additional Rent

Price on request

Total Space Available

376 SF

Floor

3

Divisible Space

376 - 376 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Contacts

broker
Alexander Zvibleman

SVN | Infinity Commercial Group

Building Details

  • For Lease $1,250.00 - $4,000.00/MO
  • Property Type Office - Creative Office
  • Property Size 2,802 SF
  • Lot Size 0.09 Acre
  • Additional Rent Price on request
  • Property Tenancy Multi-Tenant
  • Building Class A
  • Year Built 1900
  • Year Renovated 2010
  • Date Updated Aug 31, 2026

Location

  • City St Louis, MO
  • Neighborhood Downtown Saint Louis
  • Zip Code 63102
  • Market St Louis
  • Map
  • Street
  • Walk score 65/100 Somewhat Walkable
  • Transit score 57/100 Good Transit
  • Bike score 70/100 Very Bikeable
Powered by Walk Score ®

Points of Interest

8th & Pine

0.64 miles

St. Louis - Gateway Station

0.76 miles

Union Station - Stair Access

0.97 miles

Union Station

1.00 miles

Union Station - Elevator Access

1.02 miles

Missouri History Museum/Forest Park

5.38 miles

The Wild Station

5.40 miles

Forest Park - DeBaliviere Metrolink

5.46 miles

Discovery Corner Station

5.51 miles

Delmar Loop Metrolink

6.09 miles

BP

0.08 miles

Phillips 66

0.16 miles

EV Connect

0.53 miles

ChargePoint

0.88 miles

Shell

1.05 miles

Zephyr Xpress

1.21 miles

Conoco

1.27 miles

EVgo Charging Station

2.96 miles

Tesla Supercharger

3.72 miles

Electric Car Charging Station

6.94 miles

7th Cerre lot

0.16 miles

Lot B

0.25 miles

Starr Lot

0.30 miles

Stan the Man Public Parking Lot

0.36 miles

Stadium East Garage

0.37 miles

Old Cathedral Parking Lot

0.42 miles

Cupples Station Lot

0.43 miles

10th & Spruce Lot

0.43 miles

City Block 426 Lot

0.44 miles

Enterprise

0.60 miles

Custom Car Rental

1.72 miles

Jefferson Avenue Car Wash

1.87 miles

Swish Wash

3.04 miles

Sho-Off Car Wash

3.79 miles

Waterway Express

4.16 miles

The Neighborhood Car Wash

4.41 miles

Circle K

5.17 miles

Splish Splash Car Wash

5.31 miles

Saint Louis Hills Car Wash

6.33 miles

White Castle

0.04 miles

Taco Bell

0.13 miles

Rally's

0.18 miles

Eat Rite

0.22 miles

Salt + Smoke

0.34 miles

Budweiser Brew House

0.36 miles

Cardinals Nation

0.37 miles

Condado Tacos

0.39 miles

Katie's Pizza & Pasta

0.39 miles

Koibito Poké

0.39 miles

Schnucks

0.75 miles

James Henry Provisions

0.79 miles

Copia Wine Mart and Bodega

0.91 miles

The Cobblestone STL

0.92 miles

Fields Foods

1.04 miles

St. Louis Union Station

1.12 miles

Vincent's Market

1.46 miles

Save-A-Lot

1.64 miles

Midwest Pasta Company

2.39 miles

Target

2.46 miles

Saint Louis FD Engine House 2 and Repair Shop

0.57 miles

St. Louis Metropolitan Police Academy

0.61 miles

Board of Police Commissioners

0.64 miles

St Louis Metro Police

0.65 miles

St. Louis Metropolitan Police Department Downtown Police Unit

0.71 miles

Saint Louis Fire Department Station 11

1.18 miles

St. Louis Police Department Headquarters

1.27 miles

Police Substation

1.45 miles

Saint Louis City Engine House Number 7 Fire Station

1.50 miles

VA Clinic

1.81 miles

Listing Summary

  • Office Space Available at 754 S 4th Street

    Office space currently available at 754 S 4th Street adds up to a total of 2,802 square feet across 3 listing(s). The largest individual space listed offers 1,213 square feet. Property use types available for lease at this property include: street retail, general office and creative office.

  • Learn More about 754 S 4th Street

    754 S 4th Street is located in the St Louis market and pertains to the 63102 zip code. The property incorporates a total of 2,802 square feet of space. 754 S 4th Street was built in 1900. The most recent renovation work at this property was completed in 2010.

    Interested in researching more about this property? Access in-depth research on 754 S 4th Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Downtown Saint Louis neighborhood, where 754 S 4th Street is located, you can currently find 221 office space(s) for rent. In total, this amounts to 2,799,773 square feet of available office space for lease opportunities.

Contact Alexander Zvibleman
broker
Alexander Zvibleman

SVN | Infinity Commercial Group

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