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  1. Office Space
  2. MO
  3. Saint Louis

Cortex 1 - Office/Lab Space For Lease

For Lease 36,682 SF

4320 Forest Park Ave, St. Louis, MO 63110

Cortex is more than just buildings. Cortex is an innovation district that believes, “Together we can do more!” Cortex is a catalyst for innovation by bringing together big-thinking problem solvers with state-of-the-art resources, facilities, and innovative programming to inspire and drive collaboration.

Key features

  • Adjacent surface parking
  • Building signage opportunity
  • Close proximity to the new Aloft Hotel, Cortex Commons, several restaurants, including Vicia and Park Avenue Caf, and additional amenities
  • Surrounded by activated public spaces
  • Up to 36,682 SF available

Rental Details

  • Number of spaces 1
  • Total square feet available 36,682 SF
  • For Lease Price on request
  • Space Type General Office
  • Latest Update Aug 16, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
Space Available General Office Price on request 36,682 SF - -

Space Available

Space Type

General Office

Lease Rate

Price on request

Additional Rent

Price on request

Total Space Available

36,682 SF

Attachments

View Attachments

Divisible Space

9,634 - 36,682 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Build Type

Full build out

Space Available

Space Type
General Office
Lease Rate
Price on request
Total Space
36,682 SF
Space Type

General Office

Lease Rate

Price on request

Additional Rent

Price on request

Total Space Available

36,682 SF

Attachments

View Attachments

Divisible Space

9,634 - 36,682 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Build Type

Full build out

Contacts

broker
Tony Kennedy

Colliers

broker
Rebekah Bahn Kingston

Colliers

Building Details

  • For Lease Price on request
  • Property Type Office - General Office
  • Additional Rent Price on request
  • Date Updated Aug 16, 2026

Location

  • City St. Louis, MO
  • Neighborhood Central West End Saint Louis
  • Zip Code 63110
  • Market St Louis
  • Map
  • Street
  • Walk score 76/100 Very Walkable
  • Transit score 58/100 Good Transit
  • Bike score 63/100 Bikeable
Powered by Walk Score ®

Points of Interest

Missouri History Museum/Forest Park

1.85 miles

Forest Park - DeBaliviere Metrolink

1.93 miles

The Wild Station

1.94 miles

Discovery Corner Station

2.06 miles

Union Station - Elevator Access

2.55 miles

Delmar Loop Metrolink

2.57 miles

Union Station

2.58 miles

Delmar Loop

2.61 miles

Union Station - Stair Access

2.61 miles

Skinker

2.71 miles

BP

0.22 miles

QuikTrip

0.66 miles

Mobil

1.21 miles

Tesla Supercharger

1.21 miles

Crown

1.48 miles

ChargePoint

1.49 miles

Shell

1.92 miles

EVgo Charging Station

2.51 miles

EV Connect

3.10 miles

Electric Car Charging Station

3.95 miles

Cortex lot

0.03 miles

4240 and Tech Shop Parking

0.17 miles

4220 Duncan Garage

0.25 miles

Duncan/Taylor Parking Garage

0.33 miles

Clayton Avenue Parking Garage

0.40 miles

Children's Place Parking Garage

0.43 miles

Euclid Garage

0.49 miles

American Red Cross Parking Garage

0.50 miles

IKEA Parking Lot

0.50 miles

Chroma Apartments Garage

0.59 miles

Sho-Off Car Wash

0.72 miles

Swish Wash

1.17 miles

Waterway Express

1.84 miles

Circle K

2.06 miles

The Neighborhood Car Wash

2.60 miles

Jefferson Avenue Car Wash

2.61 miles

Enterprise

2.64 miles

Splish Splash Car Wash

2.69 miles

Custom Car Rental

2.74 miles

Saint Louis Hills Car Wash

4.16 miles

Vicia

0.08 miles

Taqueria Morita

0.11 miles

Subway

0.34 miles

Thai Bowl

0.35 miles

Global Quesadilla Company

0.36 miles

Five Guys

0.41 miles

Pizza Hut

0.42 miles

Jack in the Box

0.44 miles

Chick-fil-A

0.48 miles

Qdoba

0.50 miles

Schnucks

0.48 miles

Whole Foods Market

0.59 miles

N & M Food Market

0.64 miles

Fresh Thyme

0.81 miles

Straub's Market

0.86 miles

Target

1.13 miles

ALDI

1.18 miles

Save-A-Lot

1.49 miles

Soll's Gateway Market

1.56 miles

John Viviano and Sons

1.65 miles

Rehabilitation Institute of Saint Louis

0.28 miles

Walgreens

0.32 miles

Shriners Hospital for Children

0.40 miles

Grant Medical Clinic

0.44 miles

Barnes-Jewish Center for Outpatient Health

0.56 miles

Siteman Cancer Center

0.58 miles

Saint Louis City Engine House #29 Fire Station

0.61 miles

CVS Pharmacy

0.61 miles

Barnes-Jewish Hospital

0.65 miles

Saint Louis Children's Hospital

0.66 miles

Listing Summary

  • Office Space Available at 4320 Forest Park Ave

    Office space currently available at 4320 Forest Park Ave adds up to a total of 36,682 square feet across 1 listing(s). The largest individual space listed offers 36,682 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 4320 Forest Park Ave

    4320 Forest Park Ave is located in the St Louis market and pertains to the 63110 zip code. The property incorporates a total of 36,682 square feet of space.

    Interested in researching more about this property? Access in-depth research on 4320 Forest Park Ave, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the Central West End Saint Louis neighborhood, where 4320 Forest Park Ave is located, you can currently find 15 office space(s) for rent. In total, this amounts to 200,910 square feet of available office space for lease opportunities.

Contact Cortex 1 - Office/Lab Space For Lease
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