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  1. Commercial Spaces
  2. MO
  3. Saint Louis

The 22

For Lease 3,420 SF

2200 Locust Street, St. Louis, MO 63103

3,420 S.F. Ground Floor Retail Space now available for lease in "The 22" building.

The space is presently in wide-open and in gray box condition, ready for finishing touches. The 22 is a mixed-use property featuring 29 fully-renovated apartments and is located just 2 blocks from the new St. Louis CITYPARK stadium. The space is ideal for a variety of small business uses that can benefit from strong foot traffic and a significant number of residents that live in the building and immediate vicinity.

Key features

  • Located 2 blocks from St. Louis City Park MLS Stadium.
  • Ground floor below 29 fully-renovated apartments.
  • Street-level retail space.
  • Originally constructed in 1916 as a perfume factory.
  • Become part of the Downtown West resurgence.
  • Wide-Open space in grey box condition – Ready for finishes!

Rental Details

  • Number of spaces 1
  • Total square feet available 3,420 SF
  • For Lease $18.00/SF/YR
  • Space Type Mixed Use
  • Lease Type NNN
  • Latest Update Jun 19, 2025
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand

1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
2206 Mixed Use $18.00/SF/YR 3,420 SF - NNN

2206

Space Type

Mixed Use

Lease Rate

$18.00/SF/YR

Additional Rent

Price on request

Total Space Available

3,420 SF

Available Date

Immediate

Lease Type

NNN

Sublease

No

2206

Space Type
Mixed Use
Lease Rate
$18.00/SF/YR
Total Space
3,420 SF
Lease Type
NNN
Space Type

Mixed Use

Lease Rate

$18.00/SF/YR

Additional Rent

Price on request

Total Space Available

3,420 SF

Available Date

Immediate

Lease Type

NNN

Sublease

No

Contacts

broker
Ben Cherry

Manor Real Estate

CA
Caleb Anthonis

Manor Real Estate

EC
Eddie Cherry

Manor Real Estate

Building Details

  • For Lease $18.00/SF/YR
  • Property Type Mixed Use
  • Property Size 38,750 SF
  • Lot Size 7,750 SF
  • Zoning I - Central Business District
  • Additional Rent Price on request
  • # of Floors 5
  • Property Tenancy Multi-Tenant
  • Year Built 1916
  • Year Renovated 2020
  • Date Updated Jun 19, 2025

Location

  • City St. Louis, MO
  • Neighborhood Downtown West Saint Louis
  • Zip Code 63103
  • Market St Louis
  • Map
  • Street
  • Walk score 82/100 Very Walkable
  • Transit score 47/100 Some Transit
  • Bike score 60/100 Bikeable
Powered by Walk Score ®

Points of Interest

Union Station - Elevator Access

0.49 miles

Union Station

0.51 miles

Union Station - Stair Access

0.52 miles

St. Louis - Gateway Station

0.74 miles

8th & Pine

1.06 miles

Missouri History Museum/Forest Park

4.10 miles

Forest Park - DeBaliviere Metrolink

4.14 miles

The Wild Station

4.21 miles

Discovery Corner Station

4.33 miles

Delmar Loop Metrolink

4.74 miles

BP

0.46 miles

Shell

0.77 miles

Zephyr Xpress

0.86 miles

ChargePoint

0.89 miles

EV Connect

0.94 miles

Phillips 66

1.37 miles

Crown

1.65 miles

EVgo Charging Station

2.76 miles

Tesla Supercharger

2.82 miles

Electric Car Charging Station

6.03 miles

Schlafly Tap Room Lot

0.04 miles

Olive Street Parking Garage

0.23 miles

Lot 4

0.25 miles

Lot 3

0.31 miles

Lot 5

0.33 miles

Lot 6

0.36 miles

Lot 22

0.36 miles

18th & Chestnut Garage

0.37 miles

Lot 7

0.39 miles

Butler Die CO lot

0.40 miles

Enterprise

1.18 miles

Swish Wash

1.59 miles

Custom Car Rental

1.89 miles

Jefferson Avenue Car Wash

1.92 miles

Sho-Off Car Wash

2.38 miles

Waterway Express

3.40 miles

The Neighborhood Car Wash

3.88 miles

Circle K

4.16 miles

Splish Splash Car Wash

4.53 miles

Saint Louis Hills Car Wash

5.78 miles

Schlafly Tap room

0.07 miles

Syberg's Restaurant

0.17 miles

Harry's Restaurant & Bar

0.25 miles

The Pitch

0.28 miles

Kain Tayo

0.30 miles

Station Grille

0.31 miles

White Knight Diner

0.31 miles

Landry's Seafood House

0.39 miles

St. Louis Union Station Soda Fountain

0.43 miles

Medina Grill

0.64 miles

St. Louis Union Station

0.37 miles

Fields Foods

0.38 miles

Copia Wine Mart and Bodega

0.85 miles

Schnucks

0.98 miles

Save-A-Lot

1.33 miles

James Henry Provisions

1.33 miles

Target

1.40 miles

Fresh Thyme

1.47 miles

The Cobblestone STL

1.51 miles

ALDI

1.95 miles

St. Louis Police Department Headquarters

0.21 miles

VA Clinic

0.35 miles

St. Louis Metropolitan Police Department

0.38 miles

Boca Pharmacy

0.50 miles

Homer G. Phillips Memorial Hospital

0.70 miles

Saint Louis Fire Department Headquarters

0.80 miles

St Louis Metro Police

0.82 miles

Board of Police Commissioners

0.82 miles

St. Louis Metropolitan Police Academy

0.85 miles

Saint Louis FD Engine House 2 and Repair Shop

0.90 miles

Listing Summary

  • Asking Price

    The minimum asking price for spaces at 2200 Locust Street is $18.00/SF/YR.

  • Available Spaces

    The property currently has 1 space listed for lease, totaling 3,420 square feet of available space.

    This includes 1 Mixed Use space.

  • Property Characteristics

    2200 Locust Street is a Mixed Use property incorporating 38,750 square feet in total, being completed in 1916. The most recent renovations were completed in 2020.

Contact The 22
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