Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

339 Listings

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5213 South Alston Avenue
5213 South Alston Avenue, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

41,998 - 42,000 SF
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2810 Meridian
2810 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

2,851 - 19,687 SF
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$989,000
SW Durham Redevelopment Opportunity
1426 E. NC-54 Hwy, Parkwood, Durham, NC
Property Type
VacantLand
1,440 SF
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$450,000
4348 S. Alston Avenue
4348 S. Alston Avenue, Research Triangle Park, Durham, NC
Property Type
VacantLand
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$350.00 - $650.00/MO
Western Business Park
4307 Western Park Place, Bennet Place, Durham, NC
Space Type
Office
2 spaces

164 - 361 SF
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Atlas
321 W Corporation St, Old North Durham, Durham, NC
Space Type
Retail
2 spaces

418 - 1,313 SF
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$14.00 - $27.00/SF/YR
1515 North Pointe Drive
1515 North Pointe Drive, Duke Homestead, Durham, NC
Space Type
Retail
2 spaces

2,247 - 7,300 SF
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433 W. Main Street
433 W. Main Street, Warehouse District, Durham, NC
Space Type
Office
2 spaces

2,376 - 5,676 SF
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$27.00/SF/YR
2510 Meridian
2510 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
3 spaces

8,178 - 21,226 SF
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$875,000
921 Midway Avenue
921 Midway Avenue, Pleasant Drive, Durham, NC
Property Type
Retail
Built in 1989

3,895 SF
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$29.50/SF/YR
Imperial Center - Carlisle Place
4721 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

3,666 - 9,354 SF
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$16.00 - $21.00/SF/YR
New Haven Center
2310 South Miami Blvd, Taylor Estates, Durham, NC
Space Type
Office
6 spaces

1,002 - 1,870 SF
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From $25/day

Apt CoWork
Apt CoWork - Heights at Meridian
2543 Meridian Parkway, Durham, NC
Space Type
Desks
Space for up to 10 people
1 of 1
$30.50/SF/YR
Bristol Place
4819 Emperor Blvd., Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

5,388 - 17,331 SF
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Miami North Office Park
4426 South Miami Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,641 - 18,380 SF
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TBC | 4021
4021 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

5,028 - 5,957 SF
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2520 Meridian
2520 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
7 spaces

5,638 - 23,335 SF
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Price on request
949 Washington Street
949 Washington Street, Duke Park, Durham, NC
Space Type
Office
2 spaces

7,392 - 30,100 SF
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$36.00/SF/YR
Churchill Hall
5425 Page Rd, Research Triangle Park, Durham, NC
Space Type
Office
1 space

8,681 SF
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Price on request
Quadrangle V
6330 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
3 spaces

7,957 - 20,508 SF
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Price on request
RTI International Campus - Haynes Building
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

32,036 - 33,767 SF
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$27.50/SF/YR
Imperial Center - Cambridge Hall & Canterbury Hall
4815 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
6 spaces

1,747 - 15,769 SF
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From $359/month

Regus
NC, Durham - Shannon Road
3511 Shannon Road 3rd Floor, Durham, NC
Space Type
Private Offices
Space for 1 to 50 people
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$1,350,000
1001, 1003 & 1005 Broad Street
1001, 1003 & 1005 Broad Street, Old West Durham, Durham, NC
Property Type
VacantLand
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Meridian Corporate Center - 2800 Meridian Pkwy
2800 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

3,574 - 8,295 SF
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From $559/month

Spaces
Spaces - Durham - Mangum Street
555 South Mangum Street #100, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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$36.00/SF/YR
108 Morris Street
108 Morris Street, Central Park, Durham, NC
Space Type
Retail
1 space

1,606 SF
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Greenwood Commons
5410 NC-55 Hwy, Parkwood, Durham, NC
Space Type
Retail
2 spaces

1,550 - 1,820 SF
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$550,000
3719 University Dr, Suite A
3719 University Drive, Valley Run, Durham, NC
Property Type
Office
Built in 1994

1,677 SF
1 of 1
$20.00/SF/YR
3825 S Roxboro St
3825 S Roxboro St, Stratford Lakes, Durham, NC
Space Type
Retail
5 spaces

1,600 - 1,840 SF
1 of 1
Price on request
Welcome Venture Park - Building H
Welcome Venture Park - Building H, Falls Lake, Durham, NC
Space Type
Industrial
1 space

100,450 SF
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608 S Hoover Rd
608 S Hoover Rd, Wellons Village, Durham, NC
Space Type
Mixed Use
1 space

6,600 SF
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$30.50/SF/YR
Brighton Hall
1101 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

2,338 - 18,831 SF
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Price on request
2525 Meridian
2525 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
13 spaces

5,110 SF
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Price on request
Hock Plaza II
600 Douglas Street, Crest Street, Durham, NC
Space Type
Office
2 spaces

28,800 SF
1 of 1
$960,000 or $11 PSF
Imperial Center Retail/Daycare/Hotel Site/Office
Slater Road at Parliament Court , Research Triangle Park, Durham, NC
Property Type
VacantLand
1 of 1
$1,375,000
Imperial Corners Hotel Site
5422 Page Road, Research Triangle Park, Durham, NC
Property Type
VacantLand
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$19.50 - $27.14/SF/YR
200 Meredith Drive
200 Meredith Drive, Parkwood, Durham, NC
Space Type
Office
3 spaces

597 - 1,628 SF
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Price on request
Newcastle North
1035 Swabia Court, Research Triangle Park, Durham, NC
Space Type
Office
1 space

15,127 SF
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Price on request
Quintiles Plaza
4820 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
1 space

260,000 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 12.0 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 12.0 million square feet.

Current leasing options comprise 139 office listings, which represent approximately 58.16% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.41% of the total. Additionally, 56 retail listings make up 23.43% of the local leasing market. These types are supplemented by 19 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 139 13,034,738 $33.69

Retail 56 4,514,055 $27.31

Industrial 44 4,959,155 $12.21

Other 19 1,128,258 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 11 office assets, 8 industrial facilities and 6 retail properties available for purchase.

The largest share is held by Office, with 18.97% out of local properties for sale belonging to this asset type. Industrial has the next largest share at 13.79%, while Retail makes up 10.34% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 11 13,034,738

Retail 6 4,514,055

Industrial 8 4,959,155

Other 33 11,842,017

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 160 office listings, totaling 2,529,624 square feet.
Industrial: Research Triangle Park with 10 industrial listings, totaling 918,141 square feet.
Retail: Downtown Durham with 17 retail listings, totaling 45,116 square feet.