Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

329 Listings

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$28.50/SF/YR
Imperial Center - Stratford Hall
1009 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,800 - 18,993 SF
1 of 1
Price on request
One City Center
110 Corcoran St. , Central Park, Durham, NC
Space Type
Retail
3 spaces

1,789 - 6,828 SF
1 of 1
Price on request
4020 North Roxboro Street
4020 North Roxboro Street, Summer Meadow, Durham, NC
Space Type
Office
1 space

2,142 SF
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Price on request
3200 SF Retail/Office | Base Rent from $17/SF + NNN
1912 E NC 54 Hwy, Parkwood, Durham, NC
Space Type
Mixed Use
1 space

3,200 SF
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$28.50/SF/YR
Quadrangle III
6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
8 spaces

1,929 - 15,037 SF
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$375,000
2404 Dearborn Drive
2404 Dearborn Drive, Crown Point, Durham, NC
Property Type
VacantLand
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From $530/month

WeWork
WeWork - One City Center
110 Corcoran St, Durham, NC
Space Type
Private Offices
Space for 1 to 100 people
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Price on request
TBC | 4025
4025 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

13,818 - 21,984 SF
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Price on request
The Imperial Center - Nottingham Hall
4505 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,224 - 28,079 SF
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$27.50/SF/YR
The Boulevard
4125 Durham-Chapel Hill Blvd, Chapel Hill Road, Durham, NC
Space Type
Retail
2 spaces

4,056 - 5,564 SF
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Price on request
105 W. Morgan Street
105 W. Morgan Street, Central Park, Durham, NC
Space Type
Retail
4 spaces

971 - 3,307 SF
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Price on request
Quintiles Plaza
4820 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
1 space

260,000 SF
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3 of 3
Price on request
Quadrangle IV
6340 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
2 spaces

5,366 - 19,925 SF
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From $20/day

Provident1898
Provident1898
411 W. Chapel Hill St, Suite C2, Durham, NC
Space Type
Desks
Space for up to 50 people
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Price on request
600 Frontier
600 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

1,033 - 3,559 SF
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Price on request
Welcome Venture Park - Building I | Delivering Q4 2027
Welcome Venture Park - Building I, Falls Lake, Durham, NC
Space Type
Industrial
1 space

188,160 SF
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$38.00 - $44.00/SF/YR
555 Mangum
555 S Mangum St, Downtown Durham, Durham, NC
Space Type
Retail
2 spaces

1,675 - 11,760 SF
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Price on request
Boxyard RTP
900 Park Offices Drive, Research Triangle Park, Durham, NC
Space Type
Retail
1 space

960 SF
1 of 1
Price on request
2800 Meridian
2800 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
1 space

3,574 SF
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From $459/month

HQ
HQ - Imperial Raleigh
4819 Emperor Blvd., Imperial Business Park Suite 400, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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Price on request
The Village
1000-1100 N. Miami Blvd, Wellons Village, Durham, NC
Space Type
Retail
2 spaces

4,066 - 6,135 SF
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Price on request
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Space Type
Industrial
3 spaces

36,378 - 96,386 SF
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Price on request
Trust Building
212 West Main Street, Central Park, Durham, NC
Space Type
Office
5 spaces

999 - 7,642 SF
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Price on request
Welcome Venture Park
Welcome Venture Park, Glennstone, Durham, NC
Space Type
Industrial
1 space

846,010 SF
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$36.50/SF/YR
Venable Center
303 South Roxboro Street, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

4,552 - 11,446 SF
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Price on request
Hope Valley Pointe
4810 Hope Valley Road, Suite 107, Valley Brook, Durham, NC
Space Type
Retail
1 space

2,653 SF
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Price on request
Miami North Office Park
4426 South Miami Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,641 - 18,380 SF
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Price on request
Industrial Warehouse in West Durham
121 S. LaSalle Street, Old West Durham, Durham, NC
Space Type
Industrial
1 space

24,000 SF
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Price on request
Research Triangle Park - North Campus
5 Moore Drive, Research Triangle Park, Durham, NC
Space Type
Office
12 spaces

1,358 - 89,965 SF
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Price on request
433 W. Main Street
433 W. Main Street, Warehouse District, Durham, NC
Space Type
Office
2 spaces

2,376 - 5,676 SF
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Price on request
RTI International Campus - Cox & Hobbs Buildings
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

5,304 - 15,781 SF
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$29.50/SF/YR
1000 W Main
1000 W Main St, Trinity Park, Durham, NC
Space Type
Office
1 space

4,100 SF
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Price on request
Royal at Imperial Center
4222 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

8,887 - 11,303 SF
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$29.50/SF/YR
Imperial Center - Carlisle Place
4721 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

3,666 - 9,354 SF
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608 S Hoover Rd
608 S Hoover Rd, Wellons Village, Durham, NC
Space Type
Mixed Use
1 space

6,600 SF
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Price on request
Durham ID - 200 Morris Street
200 Morris Street, Central Park, Durham, NC
Space Type
Retail
1 space

2,698 SF
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Price on request
400 Park Offices
400 Park Offices Drive, Research Triangle Park, Durham, NC
Space Type
Office
1 space

959 SF
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Price on request
800 Frontier
800 Park Offices Dr, Research Triangle Park, Morrisville, NC
Space Type
Office
3 spaces

4,006 - 4,390 SF
1 of 1
$20.00/SF/YR
3825 S Roxboro St
3825 S Roxboro St, Stratford Lakes, Durham, NC
Space Type
Retail
5 spaces

1,600 - 1,840 SF
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3 of 3
Price on request
100 Meredith Dr
100 Meredith Dr, Parkwood, Durham, NC
Space Type
Office
1 space

430 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 137 office listings, which represent approximately 57.56% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.49% of the total. Additionally, 57 retail listings make up 23.95% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 137 12,839,171 $33.69

Retail 57 4,565,886 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,067,864 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,839,171

Retail 7 4,565,886

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 151 office listings, totaling 2,339,980 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.