Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

333 Listings

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Price on request
Meridian Corporate Center - 2700 Meridian Pkwy
2700 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

7,274 - 25,952 SF
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Trust Building
212 West Main Street, Central Park, Durham, NC
Space Type
Office
5 spaces

999 - 7,642 SF
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Hope Valley Pointe
4810 Hope Valley Road, Suite 107, Valley Brook, Durham, NC
Space Type
Retail
1 space

2,653 SF
1 of 1
$30.00/SF/YR
Patterson Place
3616 Witherspoon Blvd, Westgate Townes, Durham, NC
Space Type
Retail
2 spaces

2,950 - 4,593 SF
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3710 University Dr
3710 University Dr, Chapel Hill Road, Durham, NC
Space Type
Office
1 space

1,335 SF
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Price on request
2405 & 2419 E Cornwallis Rd
2405 & 2419 E Cornwallis Rd, Research Triangle Park, Durham, NC
Space Type
Land
1 space

119,790 SF
1 of 1
$20.00/SF/YR
3825 S Roxboro St
3825 S Roxboro St, Stratford Lakes, Durham, NC
Space Type
Retail
5 spaces

1,600 - 1,840 SF
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Roger's Alley
200 North Mangum Street, Downtown Durham, Durham, NC
Space Type
Retail
2 spaces

3,238 - 3,244 SF
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TBC Place II
4025 Stirrup Creek Drive, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

10,843 - 23,790 SF
1 of 1
Price on request
2525 Meridian
2525 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
14 spaces

12,882 SF
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$875,000
921 Midway Avenue
921 Midway Avenue, Pleasant Drive, Durham, NC
Property Type
Retail
Built in 1989

3,895 SF
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Price on request
SouthCourt Building
3211 Shannon Road, Valley Run, Durham, NC
Space Type
Office, Retail
10 spaces

1,007 - 19,351 SF
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Contact Broker
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Property Type
Industrial
Built in 1984

341,298 SF
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$375,000
2404 Dearborn Drive
2404 Dearborn Drive, Crown Point, Durham, NC
Property Type
VacantLand
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$18.75/SF/YR
Croasdaile Office Park
1816 Front Street, Suite 220, Croasdaile, Durham, NC
Space Type
Office
1 space

3,000 SF
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$14.00 - $27.00/SF/YR
1515 North Pointe Drive
1515 North Pointe Drive, Duke Homestead, Durham, NC
Space Type
Retail
2 spaces

2,247 - 7,300 SF
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608 S Hoover Rd
608 S Hoover Rd, Wellons Village, Durham, NC
Space Type
Mixed Use
1 space

6,600 SF
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$49.50/SF/YR
Horseshoe at Hub RTP
3151 Elion Drive, Research Triangle Park, Durham, NC
Space Type
Office, Retail
9 spaces

1,895 - 32,492 SF
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1030 & 1040 Swabia Court
1040 Swabia Court, Research Triangle Park, Durham, NC
Space Type
Office
1 space

9,630 SF
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2 of 2
$7.50 - $8.00/SF/YR
1500 E Club Blvd
1500 E Club Blvd, Crown Point, Durham, NC
Space Type
Industrial
1 space

31,710 SF
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Greenwood Commons
5410 NC-55 Hwy, Parkwood, Durham, NC
Space Type
Retail
2 spaces

1,550 - 1,820 SF
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3105 Colclough Avenue
3105 Colclough Avenue, Crown Point, Durham, NC
Property Type
Other
12.83 Acre
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RTI International Campus - Haynes Building
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

32,036 - 33,767 SF
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121 Hunt St.
121 Hunt St., Old North Durham, Durham, NC
Space Type
Mixed Use
1 space

23,657 SF
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$28.50/SF/YR
Park City
2222 NC 54, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

4,509 - 19,792 SF
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$1,490,000
Holloway Street Assemblage
2003-2013 Holloway Street, Wellons Village, Durham, NC
Property Type
VacantLand
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$28.50/SF/YR
Quadrangle III
6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
8 spaces

1,929 - 15,037 SF
1 of 1
Price on request
2500 Meridian
2500 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
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$17.00 - $21.00/SF/YR
Hamilton Centre
1415 West State Highway 54, The Landing at Southpoint, Durham, NC
Space Type
Office
3 spaces

983 - 2,074 SF
1 of 1
$18.00/SF/YR
Parkside 70
1020 S Miami Blvd, Pleasant Drive, Durham, NC
Space Type
Retail
2 spaces

6,204 - 7,905 SF
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Price on request
Woodcroft Shopping Center
4711 Hope Valley Road, Woodcroft, Durham, NC
Space Type
Retail
1 space

1,435 SF
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$2,200,000
2000, 2008 & 2014 Cheek Road
2000, 2008 & 2014 Cheek Road, Merrick Moore, Durham, NC
Property Type
VacantLand
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400 Park Offices
400 Park Offices Drive, Research Triangle Park, Durham, NC
Space Type
Office
1 space

959 SF
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$36.50/SF/YR
Venable Center
303 South Roxboro Street, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

4,552 - 11,446 SF
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1212 Broad Street, Suite B
1212 Broad Street, Suite B, Walltown, Durham, NC
Space Type
Office
1 space

1,356 SF
1 of 1
Price on request
4020 North Roxboro Street
4020 North Roxboro Street, Summer Meadow, Durham, NC
Space Type
Office
1 space

2,142 SF
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100 Meredith Dr
100 Meredith Dr, Parkwood, Durham, NC
Space Type
Office
1 space

430 SF
1 of 1
Price on request
2605 Meridian
2605 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
3 spaces

2,772 - 39,613 SF
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Renaissance Village
8128 Renaissance Parkway, Eagle's Pointe, Durham, NC
Space Type
Retail
3 spaces

1,447 - 2,185 SF
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$350.00 - $650.00/MO
Western Business Park
4307 Western Park Place, Bennet Place, Durham, NC
Space Type
Office
2 spaces

164 - 361 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 137 office listings, which represent approximately 57.56% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.49% of the total. Additionally, 57 retail listings make up 23.95% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 137 12,839,171 $33.69

Retail 57 4,565,886 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,067,864 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,839,171

Retail 7 4,565,886

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 151 office listings, totaling 2,339,980 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.