Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

331 Listings

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Price on request
2510 Meridian
2510 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
4 spaces

2,997 - 21,226 SF
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Price on request
RTI International Campus - Hill Building
3040 East Cornwallis Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

30,808 - 32,745 SF
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2 of 3

3 of 3
$1,600,000
1004 NC 54 Hwy E
1004 NC 54 Hwy E, Parkwood, Durham, NC
Property Type
VacantLand
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Price on request
800 Frontier
800 Park Offices Dr, Research Triangle Park, Morrisville, NC
Space Type
Office
3 spaces

4,006 - 4,390 SF
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4430 Hillsborough Rd
4430 Hillsborough Rd, West Hills, Durham, NC
Space Type
Mixed Use
1 space

6,552 SF
1 of 1
Price on request
2505 Meridian
2505 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
3 spaces

2,005 - 4,604 SF
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Price on request
TBC | 4020
4020 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
1 space

9,566 SF
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Price on request
129,600 SF Industrial Building for Lease
1218 Stone Park Ct, Wynterfield, Durham, NC
Space Type
Industrial
1 space

129,600 SF
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Price on request
Park Point - Edge West
4001 North Carolina 54, Research Triangle Park, Morrisville, NC
Space Type
Office
1 space

10,946 SF
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3 of 3
Price on request
Quadrangle V
6330 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Space Type
Office
3 spaces

7,957 - 20,508 SF
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$1,800,000
216-218 Rigsbee Avenue
216-218 Rigsbee Avenue, Central Park, Durham, NC
Property Type
Office
Built in 1936

10,461 SF
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$17.00 - $21.00/SF/YR
Hamilton Centre
1415 West State Highway 54, The Landing at Southpoint, Durham, NC
Space Type
Office
3 spaces

983 - 2,074 SF
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2 of 4

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4 of 4
$24.50/SF/YR
Park Forty Plaza
1000 Park Forty Plaza, Parkwood, Durham, NC
Space Type
Office
12 spaces

1,411 - 26,309 SF
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Roger's Alley
200 North Mangum Street, Downtown Durham, Durham, NC
Space Type
Retail
2 spaces

3,238 - 3,244 SF
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5 of 5
Price on request
The Tower at Mutual Plaza
411 West Chapel Hill Street, Downtown Durham, Durham, NC
Space Type
Office, Retail
7 spaces

1,489 - 14,357 SF
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4 of 4
Price on request
Quintiles Plaza
4820 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
1 space

260,000 SF
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$36.50/SF/YR
Venable Center
303 South Roxboro Street, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

4,552 - 11,446 SF
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Price on request
Old Chapel Hill Road Assemblage
4138 & 4142 Old Chapel Hill Road, Westgate Townes, Durham, NC
Space Type
Land
1 space

77,101 SF
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Price on request
2520 Meridian
2520 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
7 spaces

5,638 - 23,335 SF
1 of 2

2 of 2
Price on request
Welcome Venture Park - Building E
Welcome Venture Park - Building E, Glennstone, Durham, NC
Space Type
Industrial
1 space

23,000 SF
1 of 1
Price on request
1023 S Miami Blvd
1023 S Miami Blvd, Pleasant Drive, Durham, NC
Space Type
Flex Space
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Price on request
Renaissance Village
8128 Renaissance Parkway, Eagle's Pointe, Durham, NC
Space Type
Retail
3 spaces

1,447 - 2,185 SF
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5 of 5
$30.50/SF/YR
Brighton Hall
1101 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

2,298 - 7,519 SF
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$19.00 - $23.00/SF/YR
Westgate II Office Park
3622 Lyckan Pkwy, Chapel Hill Road, Durham, NC
Space Type
Office
3 spaces

303 - 750 SF
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Price on request
Parkway Plaza
4215 University Drive, Valley Run, Durham, NC
Space Type
Retail
1 space

3,173 SF
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5 of 5
Price on request
TBC | 4021
4021 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

5,028 - 5,957 SF
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2 of 4

3 of 4

4 of 4
$28.50/SF/YR
Imperial Center - Stratford Hall
1009 Slater Road, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

1,800 - 18,993 SF
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2 of 2
Price on request
Welcome Venture Park - Building J | Delivering Q4 2027
Welcome Venture Park - Building J, Ravenstone, Durham, NC
Space Type
Industrial
1 space

252,117 SF
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$20.00/SF/YR
2919 Colony Road
2919 Colony Road, Colony Park, Durham, NC
Space Type
Office
1 space

3,867 SF
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$4,500.00/MO
5112 Neal Rd
5112 Neal Road, Bennet Place, Durham, NC
Space Type
Office
1 space

3,000 SF
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Price on request
Greenwood Commons
5410 NC-55 Hwy, Parkwood, Durham, NC
Space Type
Retail
2 spaces

1,550 - 1,820 SF
1 of 1
$2,650,745
5412 S Miami Blvd
5412 S Miami Blvd, Research Triangle Park, Durham, NC
Property Type
Retail
Built in 2004

6,534 SF
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Price on request
3200 SF Retail/Office | Base Rent from $17/SF + NNN
1912 E NC 54 Hwy, Parkwood, Durham, NC
Space Type
Mixed Use
1 space

3,200 SF
1 of 3

2 of 3

3 of 3
Price on request
555 Mangum
555 South Mangum Street, Downtown Durham, Durham, NC
Space Type
Office
7 spaces

1,832 - 24,190 SF
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From $359/month

Regus
Regus - Durham - Shannon Road
3511 Shannon Road 3rd Floor, Durham, NC
Space Type
Private Offices
Space for 1 to 15 people
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Kittcreek Commons
5125 NC-55 Hwy, Unit 103, Parkwood, Durham, NC
Space Type
Retail
1 space

1,168 SF
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Price on request
3105 Colclough Avenue
3105 Colclough Avenue, Crown Point, Durham, NC
Property Type
Other
12.83 Acre
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Price on request
TBC | 4022
4022 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
1 space

6,832 SF
1 of 1
Price on request
2700 Meridian
2700 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
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Price on request
600 Frontier
600 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

1,033 - 3,559 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 11.8 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 11.8 million square feet.

Current leasing options comprise 137 office listings, which represent approximately 57.56% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.49% of the total. Additionally, 57 retail listings make up 23.95% of the local leasing market. These types are supplemented by 18 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 137 12,839,171 $33.69

Retail 57 4,565,886 $27.22

Industrial 44 4,710,214 $14.9

Other 18 1,067,864 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 10 office assets, 7 industrial facilities and 7 retail properties available for purchase.

The largest share is held by Office, with 17.24% out of local properties for sale belonging to this asset type. Retail has the next largest share at 12.07%, while Industrial makes up 12.07% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 10 12,839,171

Retail 7 4,565,886

Industrial 7 4,710,214

Other 34 11,870,668

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 151 office listings, totaling 2,339,980 square feet.
Industrial: Research Triangle Park with 11 industrial listings, totaling 1,016,964 square feet.
Retail: Downtown Durham with 18 retail listings, totaling 71,391 square feet.