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For Lease

46 Second Street

46 Second Street, Cambridge, MA 02141

1,584

SF Available
Located between Otis St and Thorndike St off of 2nd St in the heart of East Cambridge. Just a block from the Charles River and Lechmere Canal.Discover 46 2nd St, 1,584 SqFt of office space in the heart of East Cambridge. This two level office space is on the 2nd and 3rd floors of a quaint Cambridge building. The building features central air cooling and hardwood floors. Its location features nearby urban amenities in a walkable neighborhood while also being nestled on a calmer side street. Versatile office space suitable for various businesses.

Key features

  • Central Air Cooling
  • Hardwood Floors
  • Nearby transit
  • Prime location in East Cambridge, MA
  • Street Parking
  • Versatile office space suitable for various businesses
  • Walkable neighborhood

Rental Details

  • Number of spaces 1
  • Total square feet available 1,584 SF
  • For Lease $29.00/SF/YR
  • Space Types General Office
  • Lease Type Modified Gross
  • Date Updated May 17, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

46 2nd St

  • Space Type General Office
  • Lease Rate $29.00/SF/YR
  • Total Space Available 1,584 SF
  • Floor 2 & 3
  • Divisible Space 1,584 - 1,584 SF
  • Available Date Immediate
  • Lease Type Modified Gross
  • Renewal Option Yes
  • Sublease No

Modified gross lease with escalation for real estate taxes, insurance, and operating expenses.

broker
Albert Bouchie

Gibson Commercial

Contacts

broker
Albert Bouchie

Gibson Commercial

Building Details

  • For Lease $29.00/SF/YR
  • Property Type Office - General Office
  • Property Size 3,222 SF
  • Lot Size 0.05 Acre
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1826
  • Date Updated May 17, 2026

Attachments

  • Property Brochure 1 ()opens in new window

Getting Around

  • Walk Score ®

    Walker's Paradise (96)
  • Transit Score ®

    Excellent Transit (85)
  • Bike Score ®

    Biker's Paradise (98)
Powered by Walk Score ®

Location

  • City Cambridge, MA
  • Neighborhood East Cambridge
  • Zip Code 02141
  • Market Boston
  • Map
  • Street

Points of Interest

Union Square

0.93 miles

Sullivan Square

1.01 miles

North Station

1.03 miles

Park Street

1.23 miles

Green Line (Inbound) | Red Line (All Trains)

1.26 miles

Central

1.31 miles

Boylston

1.35 miles

Downtown Crossing

1.36 miles

Back Bay

1.55 miles

Shell

0.29 miles

ChargePoint

0.84 miles

JuiceBar

0.84 miles

Speedway

0.88 miles

Pearl Street Auto Sales

1.32 miles

Tesla Destination Charger

1.41 miles

Gulf

1.44 miles

Tesla Supercharging Station

1.49 miles

Sunoco

1.57 miles

Museum of Science Parking Garage

0.34 miles

84 Athenaeum St Garage

0.42 miles

Kendall Square Garage

0.46 miles

Kendall Square Parking

0.47 miles

One Kendall Square Garage

0.57 miles

One Memorial Garage

0.58 miles

Cambridge Center Garage

0.67 miles

Ford Lot

0.70 miles

E51 Lot

0.70 miles

Somerville No Touch Car Wash

0.88 miles

Avis

1.21 miles

Enterprise

1.45 miles

Alamo

1.62 miles

Prestige

2.02 miles

Somerville Car Wash

2.05 miles

Hertz Rent a Car Returns

2.42 miles

Enterprise Rent-a-Car Returns

2.45 miles

Alamo Car Rental Return

2.45 miles

Taco Bell

0.13 miles

Au Bon Pain

0.14 miles

Olive Cafe

0.15 miles

Dunkin'

0.19 miles

Desfina

0.19 miles

Kendall House of Pizza

0.20 miles

Aram's #2 House of Pizza

0.20 miles

The Cheesecake Factory

0.22 miles

The Lexington

0.23 miles

Star Market

0.39 miles

Marshalls

0.47 miles

Brothers Marketplace

0.56 miles

Whole Foods Market

0.75 miles

Target

0.76 miles

Vinal General Store

0.87 miles

getir: groceries in minutes

0.87 miles

DeLuca's Market

1.03 miles

Tropical Dimension Food Store

1.05 miles

CVS Pharmacy

0.19 miles

Cambridge Medical Supply

0.21 miles

East Cambridge Care Center

0.41 miles

Cambridge Police Department

0.42 miles

Rite Aid

0.45 miles

Passport Health Cambridge Travel Clinic

0.53 miles

State Police Boston Barracks

0.53 miles

Massachusetts Eye and Ear

0.65 miles

Massachusetts General Hospital

0.69 miles

46 Second Street Listing Summary

  • Office Space Available at 46 Second Street

    Office space currently available at 46 Second Street adds up to a total of 1,584 square feet across 1 listing(s). The largest individual space listed offers 1,584 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 46 Second Street

    46 Second Street is located in the Boston market and pertains to the 02141 zip code. The property incorporates a total of 1,584 square feet of space. 46 Second Street was built in 1826.

    Interested in researching more about this property? Access in-depth research on 46 Second Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the East Cambridge neighborhood, where 46 Second Street is located, you can currently find 39 office space(s) for rent. In total, this amounts to 597,921 square feet of available office space for lease opportunities.

Contact Listing Broker
broker
Albert Bouchie

Gibson Commercial

  1. 1Main information
  2. 2Extra information
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