• Property Lists
  • Listings
    • Commercial Real Estate
  • Comparables
  • Owners
  • Maps
  • Resources
    • Learning Center
    • Blog
Add a Listing Advertise
  1. Office Space
  2. MA
  3. Medford - Waltham
  4. Cambridge

46 Second Street

For Lease 1,584 SF

46 Second Street, Cambridge, MA 02141

Located between Otis St and Thorndike St off of 2nd St in the heart of East Cambridge. Just a block from the Charles River and Lechmere Canal.Discover 46 2nd St, 1,584 SqFt of office space in the heart of East Cambridge. This two level office space is on the 2nd and 3rd floors of a quaint Cambridge building. The building features central air cooling and hardwood floors. Its location features nearby urban amenities in a walkable neighborhood while also being nestled on a calmer side street. Versatile office space suitable for various businesses.

Key features

  • Central Air Cooling
  • Hardwood Floors
  • Nearby transit
  • Prime location in East Cambridge, MA
  • Street Parking
  • Versatile office space suitable for various businesses
  • Walkable neighborhood

Rental Details

  • Number of spaces 1
  • Total square feet available 1,584 SF
  • For Lease $29.00/SF/YR
  • Space Type General Office
  • Lease Type Modified Gross
  • Latest Update Sep 23, 2026
View Attachment
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
46 2nd St General Office $29.00/SF/YR 1,584 SF 2 & 3 Modified Gross

46 2nd St

Space Type

General Office

Lease Rate

$29.00/SF/YR

Additional Rent

Price on request

Total Space Available

1,584 SF

Floor

2 & 3

Divisible Space

1,584 - 1,584 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Modified gross lease with escalation for real estate taxes, insurance, and operating expenses.

46 2nd St

Space Type
General Office
Lease Rate
$29.00/SF/YR
Total Space
1,584 SF
Floor
2 & 3
Lease Type
Modified Gross
Space Type

General Office

Lease Rate

$29.00/SF/YR

Additional Rent

Price on request

Total Space Available

1,584 SF

Floor

2 & 3

Divisible Space

1,584 - 1,584 SF

Available Date

Immediate

Lease Type

Modified Gross

Renewal Option

Yes

Sublease

No

Modified gross lease with escalation for real estate taxes, insurance, and operating expenses.

Contacts

broker
Albert Bouchie

Gibson Commercial

Building Details

  • For Lease $29.00/SF/YR
  • Property Type Office - General Office
  • Property Size 3,222 SF
  • Lot Size 0.05 Acre
  • Additional Rent Price on request
  • Property Tenancy Multi-Tenant
  • Building Class B
  • Year Built 1826
  • Date Updated Sep 23, 2026

Location

  • City Cambridge, MA
  • Neighborhood East Cambridge
  • Zip Code 02141
  • Market Boston
  • Map
  • Street
  • Walk score 96/100 Walker's Paradise
  • Transit score 85/100 Excellent Transit
  • Bike score 98/100 Biker's Paradise
Powered by Walk Score ®

Points of Interest

Kendall/MIT

0.62 miles

Union Square

0.93 miles

Sullivan Square

1.01 miles

North Station

1.03 miles

Park Street

1.23 miles

Green Line (Inbound) | Red Line (All Trains)

1.26 miles

Central

1.31 miles

Boylston

1.35 miles

Downtown Crossing

1.36 miles

Back Bay

1.55 miles

Tesla Supercharger

0.13 miles

Shell

0.29 miles

ChargePoint

0.84 miles

JuiceBar

0.84 miles

Speedway

0.88 miles

Pearl Street Auto Sales

1.32 miles

Tesla Destination Charger

1.41 miles

Gulf

1.44 miles

Tesla Supercharging Station

1.49 miles

Sunoco

1.57 miles

First Street Garage

0.05 miles

Museum of Science Parking Garage

0.34 miles

84 Athenaeum St Garage

0.42 miles

Kendall Square Garage

0.46 miles

Kendall Square Parking

0.47 miles

One Kendall Square Garage

0.57 miles

One Memorial Garage

0.58 miles

Cambridge Center Garage

0.67 miles

Ford Lot

0.70 miles

E51 Lot

0.70 miles

Zipcar

0.71 miles

Somerville No Touch Car Wash

0.88 miles

Avis

1.21 miles

Enterprise

1.45 miles

Alamo

1.62 miles

Prestige

2.02 miles

Somerville Car Wash

2.05 miles

Hertz Rent a Car Returns

2.42 miles

Enterprise Rent-a-Car Returns

2.45 miles

Alamo Car Rental Return

2.45 miles

Blaze Pizza

0.09 miles

Taco Bell

0.13 miles

Au Bon Pain

0.14 miles

Olive Cafe

0.15 miles

Dunkin'

0.19 miles

Desfina

0.19 miles

Kendall House of Pizza

0.20 miles

Aram's #2 House of Pizza

0.20 miles

The Cheesecake Factory

0.22 miles

The Lexington

0.23 miles

Cambridgeside

0.15 miles

Star Market

0.39 miles

Marshalls

0.47 miles

Brothers Marketplace

0.56 miles

Whole Foods Market

0.75 miles

Target

0.76 miles

Vinal General Store

0.87 miles

getir: groceries in minutes

0.87 miles

DeLuca's Market

1.03 miles

Tropical Dimension Food Store

1.05 miles

Cambridge Fire Department

0.10 miles

CVS Pharmacy

0.19 miles

Cambridge Medical Supply

0.21 miles

East Cambridge Care Center

0.41 miles

Cambridge Police Department

0.42 miles

Rite Aid

0.45 miles

Passport Health Cambridge Travel Clinic

0.53 miles

State Police Boston Barracks

0.53 miles

Massachusetts Eye and Ear

0.65 miles

Massachusetts General Hospital

0.69 miles

Listing Summary

  • Office Space Available at 46 Second Street

    Office space currently available at 46 Second Street adds up to a total of 1,584 square feet across 1 listing(s). The largest individual space listed offers 1,584 square feet. Property use types available for lease at this property include: general office.

  • Learn More about 46 Second Street

    46 Second Street is located in the Boston market and pertains to the 02141 zip code. The property incorporates a total of 1,584 square feet of space. 46 Second Street was built in 1826.

    Interested in researching more about this property? Access in-depth research on 46 Second Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the East Cambridge neighborhood, where 46 Second Street is located, you can currently find 46 office space(s) for rent. In total, this amounts to 621,748 square feet of available office space for lease opportunities.

Contact Albert Bouchie
broker
Albert Bouchie

Gibson Commercial

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Nearby Listings

24 Thorndike

24 Thorndike

24 Thorndike Street, Cambridge, MA
$32.00 - $40.00/SF/YR
Property
  • Office
  • 15,750 SF
Availability
  • 2 Spaces
  • 5,050 SF
Bulfinch Square

Bulfinch Square

43-47 Thorndike Street, Cambridge, MA
Price on request
Property
  • Office
  • 59,805 SF
Availability
  • 8 Spaces
  • 25,360 SF
Forty Thorndike

Forty Thorndike

40 Thorndike Street, Cambridge, MA
Price on request
Property
  • Office
  • 500,000 SF
Availability
  • 24 Spaces
  • 452,974 SF
1 Canal Park

1 Canal Park

1 Canal Park, Cambridge, MA
$103.00 - $106.00/SF/YR
Property
  • Office
  • 104,910 SF
Availability
  • 3 Spaces
  • 61,660 SF
CambridgeSide - 100 Cambridgeside Place

CambridgeSide - 100 Cambridgeside Place

100 Cambridgeside Place, Cambridge, MA
Price on request
Property
  • Office
  • 162,000 SF
Availability
  • 1 Space
  • 165,000 SF

Popular Searches

  • Boston Office Space for Rent
  • Cambridge Office Space for Rent
  • Waltham Office Space for Rent
  • Providence Office Space for Rent
  • Woburn Office Space for Rent
  • Worcester Office Space for Rent
  • Lowell Office Space for Rent
  • Norwood Office Space for Rent
  • Newton Office Space for Rent
  • Wellesley Office Space for Rent
  • Boston Commercial Real Estate
  • Providence Commercial Real Estate
  • Worcester Commercial Real Estate
  • Lowell Commercial Real Estate
  • Manchester Commercial Real Estate
  • Waltham Commercial Real Estate
  • Lawrence Commercial Real Estate
  • Brockton Commercial Real Estate
  • Somerville Commercial Real Estate
  • Lynn Commercial Real Estate
  • Blog
  • X
  • Facebook
  • Instagram
  • LinkedIn
  • About
  • Our Services
  • Contact Us
  • Sitemaps
  • Privacy Policy
  • Your CA Privacy Rights
  • Terms Of Service
  • FAQ

Customer Service

  • (718)715-1758
  • Contact us
Copyright 2003-2026, PropertyShark.com