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  1. Office Space
  2. MA
  3. Medford - Waltham
  4. Waltham

283-293 Second Avenue

For Lease 18,050 SF

283-293 Second Avenue, Waltham, MA 02451

The flexible layout accommodates a wide range of industrial, flex, medical, and service uses. Located within Waltham’s established commercial and lab corridor, the site offers excellent access to I-95/Route 128, Route 2, and Route 20, along with proximity to Main Street amenities. 

Rental Details

  • Number of spaces 1
  • Total square feet available 18,050 SF
  • For Lease Price on request
  • Space Type Medical Office
  • Latest Update Sep 1, 2026
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True

1 Space Available

Space Name Space Type Lease Rate Total Space Floor Lease Type Expand
Full Building Medical Office Price on request 18,050 SF - -

Full Building

Space Type

Medical Office

Lease Rate

Price on request

Additional Rent

Price on request

Total Space Available

18,050 SF

Divisible Space

18,050 - 18,050 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Turnkey

No

128 CRE is pleased to offer 283–293 Second Avenue in Waltham, MA, an 18,050 SF single-story flex building situated on a 1.03-acre (45,000 SF) lot, available for purchase or lease. The property is currently fully leased to an animal hospital that plans to vacate at lease expiration, creating a near-term opportunity for an owner-user to acquire and occupy the asset within two years. 

Full Building

Space Type
Medical Office
Lease Rate
Price on request
Total Space
18,050 SF
Space Type

Medical Office

Lease Rate

Price on request

Additional Rent

Price on request

Total Space Available

18,050 SF

Divisible Space

18,050 - 18,050 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Turnkey

No

128 CRE is pleased to offer 283–293 Second Avenue in Waltham, MA, an 18,050 SF single-story flex building situated on a 1.03-acre (45,000 SF) lot, available for purchase or lease. The property is currently fully leased to an animal hospital that plans to vacate at lease expiration, creating a near-term opportunity for an owner-user to acquire and occupy the asset within two years. 

Contacts

1L
128 CRE Centralized Leasing

128 CRE

Building Details

  • For Lease Price on request
  • Property Type Office
  • Property Size 18,050 SF
  • Lot Size 1.03 Acre
  • Additional Rent Price on request
  • Date Updated Sep 1, 2026

Location

  • City Waltham, MA
  • Neighborhood West End Waltham
  • Zip Code 02451
  • Market Boston
  • Map
  • Street
  • Walk score 29/100 Car-Dependent
  • Transit score 32/100 Some Transit
  • Bike score 24/100 Somewhat Bikeable
Powered by Walk Score ®

Points of Interest

Waltham

1.79 miles

Wellesley Farms

4.59 miles

Eliot

5.40 miles

Wellesley Hills

5.41 miles

Needham Heights

6.72 miles

Cleveland Circle

6.94 miles

Reservoir

7.01 miles

Davis

7.30 miles

Elevator to Harvard MBTA station

7.45 miles

Brattle Square - Bus Tunnel

7.45 miles

Shell

0.70 miles

Sunoco

1.02 miles

Gulf

1.37 miles

Speedway

1.39 miles

Mobil

1.40 miles

Watch City Petro

1.45 miles

Central Parking Lot Charging Station

1.65 miles

Crescent Street Lot Charging Station

1.83 miles

Walnut Street Lot Charging Station

1.85 miles

JuiceBar

2.16 miles

230 CityPoint

0.24 miles

Courtyard Marriott

0.76 miles

Prospect Hill Lot

0.94 miles

Tower Lot

1.28 miles

Heller Lot

1.37 miles

Kutz Lot

1.42 miles

Hassenfeld Lot - Brandeis University

1.51 miles

East Lot

1.55 miles

Bernstein-Marcus Lot

1.63 miles

Admissions Lot

1.67 miles

Quick & Clean Car Wash

1.54 miles

Enterprise

1.78 miles

Waltham Car Wash

1.91 miles

Perfection Car Wash

3.40 miles

Enterprise rent-a-car

3.40 miles

Belmont Car Wash and Detailing

3.82 miles

Mass Ave Car Wash

4.52 miles

AAFES Car Wash

5.23 miles

Zipcar

5.42 miles

Wellesley Car Wash

6.04 miles

Osteria Posto

0.42 miles

Bonefish Grill

0.45 miles

Dunkin' Donuts

0.51 miles

D'Angelo

0.52 miles

Jake & Joe's

0.59 miles

The Federal

0.63 miles

Not Your Average Joe's

0.64 miles

Ruth's Chris Steak House

0.64 miles

HonesT

0.69 miles

Jimmy John's

0.69 miles

Marshalls

0.47 miles

Market Basket

0.52 miles

Kev's Kwik Market

1.20 miles

Hannaford

1.35 miles

Brothers Marketplace

1.65 miles

Waltham India Market

1.86 miles

Patel Brothers

1.94 miles

Star Market

2.30 miles

Shaw's

2.60 miles

Ocean State Job Lot

2.70 miles

Boston IVF Fertility Clinic

0.29 miles

Mass General Waltham

0.58 miles

AFC Urgent Care

1.05 miles

Walgreens

1.16 miles

Watch City Pharmacy

1.18 miles

Waltham Fire Department

1.32 miles

Hannaford Pharmacy

1.34 miles

CVS Pharmacy

1.40 miles

Waltham Police Department

1.55 miles

Boston Children's at Waltham

1.56 miles

Listing Summary

  • Office Space Available at 283-293 Second Avenue

    Office space currently available at 283-293 Second Avenue adds up to a total of 18,050 square feet across 1 listing(s). The largest individual space listed offers 18,050 square feet. Property use types available for lease at this property include: medical office.

  • Learn More about 283-293 Second Avenue

    283-293 Second Avenue is located in the Boston market and pertains to the 02451 zip code. The property incorporates a total of 18,050 square feet of space.

    Interested in researching more about this property? Access in-depth research on 283-293 Second Avenue, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the West End Waltham neighborhood, where 283-293 Second Avenue is located, you can currently find 29 office space(s) for rent. In total, this amounts to 1,114,925 square feet of available office space for lease opportunities.

Contact 128 CRE Centralized Leasing
1L
128 CRE Centralized Leasing

128 CRE

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