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For Lease

283-293 Second Avenue

283-293 Second Avenue, Waltham, MA 02451

18,050

SF Available

The flexible layout accommodates a wide range of industrial, flex, medical, and service uses. Located within Waltham’s established commercial and lab corridor, the site offers excellent access to I-95/Route 128, Route 2, and Route 20, along with proximity to Main Street amenities. 

Rental Details

  • Number of spaces 1
  • Total square feet available 18,050 SF
  • For Lease Contact for pricing
  • Space Types Medical Office
  • Date Updated Apr 29, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

True

For Lease 1 Space Available

Full Building

  • Space Type Medical Office
  • Lease Rate Contact for pricing
  • Total Space Available 18,050 SF
  • Divisible Space 18,050 - 18,050 SF
  • Available Date Immediate
  • Renewal Option Yes
  • Sublease No

128 CRE is pleased to offer 283–293 Second Avenue in Waltham, MA, an 18,050 SF single-story flex building situated on a 1.03-acre (45,000 SF) lot, available for purchase or lease. The property is currently fully leased to an animal hospital that plans to vacate at lease expiration, creating a near-term opportunity for an owner-user to acquire and occupy the asset within two years. 

broker
128 CRE Centralized Leasing

128 CRE

Contacts

broker
128 CRE Centralized Leasing

128 CRE

Building Details

  • For Lease Contact for pricing
  • Property Type Office
  • Property Size 18,050 SF
  • Lot Size 1.03 Acre
  • Date Updated Apr 29, 2026

Getting Around

  • Walk Score ®

    Car-Dependent (29)
  • Transit Score ®

    Some Transit (32)
  • Bike Score ®

    Somewhat Bikeable (24)
Powered by Walk Score ®

Location

  • City Waltham, MA
  • Neighborhood West End Waltham
  • Zip Code 02451
  • Market Boston

Points of Interest

Wellesley Farms

4.59 miles

Eliot

5.40 miles

Wellesley Hills

5.41 miles

Needham Heights

6.72 miles

Cleveland Circle

6.94 miles

Reservoir

7.01 miles

Davis

7.30 miles

Elevator to Harvard MBTA station

7.45 miles

Brattle Square - Bus Tunnel

7.45 miles

Sunoco

1.02 miles

Gulf

1.37 miles

Speedway

1.39 miles

Mobil

1.40 miles

Watch City Petro

1.45 miles

Central Parking Lot Charging Station

1.65 miles

Crescent Street Lot Charging Station

1.83 miles

Walnut Street Lot Charging Station

1.85 miles

JuiceBar

2.16 miles

Courtyard Marriott

0.76 miles

Prospect Hill Lot

0.94 miles

Tower Lot

1.28 miles

Heller Lot

1.37 miles

Kutz Lot

1.42 miles

Hassenfeld Lot - Brandeis University

1.51 miles

East Lot

1.55 miles

Bernstein-Marcus Lot

1.63 miles

Admissions Lot

1.67 miles

Enterprise

1.78 miles

Waltham Car Wash

1.91 miles

Perfection Car Wash

3.40 miles

Enterprise rent-a-car

3.40 miles

Belmont Car Wash and Detailing

3.82 miles

Mass Ave Car Wash

4.52 miles

AAFES Car Wash

5.23 miles

Zipcar

5.42 miles

Wellesley Car Wash

6.04 miles

Bonefish Grill

0.45 miles

Dunkin' Donuts

0.51 miles

D'Angelo

0.52 miles

Jake & Joe's

0.59 miles

The Federal

0.63 miles

Not Your Average Joe's

0.64 miles

Ruth's Chris Steak House

0.64 miles

HonesT

0.69 miles

Jimmy John's

0.69 miles

Market Basket

0.52 miles

Kev's Kwik Market

1.20 miles

Hannaford

1.35 miles

Brothers Marketplace

1.65 miles

Waltham India Market

1.86 miles

Patel Brothers

1.94 miles

Star Market

2.30 miles

Shaw's

2.60 miles

Ocean State Job Lot

2.70 miles

Mass General Waltham

0.58 miles

AFC Urgent Care

1.05 miles

Walgreens

1.16 miles

Watch City Pharmacy

1.18 miles

Waltham Fire Department

1.32 miles

Hannaford Pharmacy

1.34 miles

CVS Pharmacy

1.40 miles

Waltham Police Department

1.55 miles

Boston Children's at Waltham

1.56 miles

283-293 Second Avenue Listing Summary

  • Office Space Available at 283-293 Second Avenue

    Office space currently available at 283-293 Second Avenue adds up to a total of 18,050 square feet across 1 listing(s). The largest individual space listed offers 18,050 square feet. Property use types available for lease at this property include: medical office.

  • Learn More about 283-293 Second Avenue

    283-293 Second Avenue is located in the Boston market and pertains to the 02451 zip code. The property incorporates a total of 18,050 square feet of space.

    Interested in researching more about this property? Access in-depth research on 283-293 Second Avenue, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

  • Get to Know the Neighborhood

    In the West End Waltham neighborhood, where 283-293 Second Avenue is located, you can currently find 14 office space(s) for rent. In total, this amounts to 149,678 square feet of available office space for lease opportunities.

Contact Listing Broker
broker
128 CRE Centralized Leasing

128 CRE

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