Durham, NC Commercial Real Estate

Search commercial property for lease or for sale and view the Market Overview section below for local stats and insights.

335 Listings

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Durham ID - 300 Morris Street
300 Morris Street, Central Park, Durham, NC
Space Type
Office
5 spaces

1,529 - 51,444 SF
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$425,000
100 E Parrish St Suite 150
100 E Parrish St Suite 150, Downtown Durham, Durham, NC
Property Type
Office
Built in 1984

1,516 SF
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TBC | 4021
4021 Stirrup Creek Dr, Research Triangle Park, Durham, NC
Space Type
Office
3 spaces

5,028 - 5,957 SF
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Atlas
321 W Corporation St, Old North Durham, Durham, NC
Space Type
Retail
2 spaces

418 - 1,313 SF
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One City Center
110 Corcoran St. , Central Park, Durham, NC
Space Type
Retail
3 spaces

1,789 - 6,828 SF
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$1,750,000
2322 So-Hi Drive
2322 So-Hi Drive, Research Triangle Park, Durham, NC
Property Type
VacantLand
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The Tower at Mutual Plaza
411 West Chapel Hill Street, Downtown Durham, Durham, NC
Space Type
Office, Retail
6 spaces

1,489 - 14,357 SF
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Park Point - Edge West
4001 North Carolina 54, Research Triangle Park, Morrisville, NC
Space Type
Office
1 space

10,946 SF
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$1,700.00/MO
5102 Durham-Chapel Hill Blvd, Suite 203
5102 Durham-Chapel Hill Blvd, Suite 203, Garret Farms - Porchlight - Hartley, Durham, NC
Space Type
Office
1 space

850 SF
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$28.50/SF/YR
Park City
2222 NC 54, Research Triangle Park, Durham, NC
Space Type
Office
5 spaces

4,509 - 19,792 SF
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Price on request
1023 S Miami Blvd
1023 S Miami Blvd, Pleasant Drive, Durham, NC
Space Type
Flex Space
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From $359/month

Regus
NC, Durham - Shannon Road
3511 Shannon Road 3rd Floor, Durham, NC
Space Type
Private Offices
Space for 1 to 50 people
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Roger's Alley
200 North Mangum Street, Downtown Durham, Durham, NC
Space Type
Retail
3 spaces

2,905 - 3,244 SF
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$28.50/SF/YR
2525 Meridian
2525 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
6 spaces

2,302 - 15,151 SF
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$1,600,000
1004 NC 54 Hwy E
1004 NC 54 Hwy E, Parkwood, Durham, NC
Property Type
VacantLand
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Meridian Corporate Center - 2800 Meridian Pkwy
2800 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
2 spaces

3,574 - 8,295 SF
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Diamond View III
359 Blackwell St, Downtown Durham, Durham, NC
Space Type
Office
5 spaces

4,552 - 87,180 SF
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Price on request
3710 University Dr
3710 University Dr, Chapel Hill Road, Durham, NC
Space Type
Office
1 space

1,335 SF
1 of 1
Price on request
2510 Meridian
2510 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
4 spaces

2,997 - 21,226 SF
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Price on request
American Tobacco Campus
318 Blackwell Street, Downtown Durham, Durham, NC
Space Type
Office
2 spaces

12,574 - 15,149 SF
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Price on request
400 Frontier
400 Park Offices Dr, Research Triangle Park, Durham, NC
Space Type
Office
4 spaces

488 - 7,916 SF
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Price on request
Royal at Imperial Center
4222 Emperor Blvd, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

8,887 - 11,303 SF
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$24.50/SF/YR
Park Forty Plaza
1000 Park Forty Plaza, Parkwood, Durham, NC
Space Type
Office
13 spaces

1,411 - 26,309 SF
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$22.00/SF/YR
201 E. Main Street
201 E. Main Street, Downtown Durham, Durham, NC
Space Type
Retail
1 space

3,057 SF
1 of 1
Price on request
2520 Meridian
2520 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
5 spaces

1,520 - 9,096 SF
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$1,350,000
1001, 1003 & 1005 Broad Street
1001, 1003 & 1005 Broad Street, Old West Durham, Durham, NC
Property Type
VacantLand
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$27.50/SF/YR
The Boulevard
4125 Durham-Chapel Hill Blvd, Chapel Hill Road, Durham, NC
Space Type
Retail
2 spaces

4,056 - 5,564 SF
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$30.50/SF/YR
Winchester Place
4309 Emperor Blvd. , Research Triangle Park, Durham, NC
Space Type
Office
6 spaces

2,870 - 17,365 SF
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$24.00/SF/YR
Meridian Corporate Center - 2530 Meridian Pkwy
2530 Meridian Pkwy, Copper Creek, Durham, NC
Space Type
Office
6 spaces

1,883 - 6,629 SF
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$30.00/SF/YR
YORKSHIRE PLACE
4307 Emperor Boulevard, Research Triangle Park, Durham, NC
Space Type
Office
2 spaces

3,780 - 27,822 SF
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Price on request
2700 Meridian
2700 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
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Hope Valley Pointe
4810 Hope Valley Road, Suite 107, Valley Brook, Durham, NC
Space Type
Retail
1 space

2,653 SF
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$30.00/SF/YR
Patterson Place
3616 Witherspoon Blvd, Westgate Townes, Durham, NC
Space Type
Retail
2 spaces

2,950 - 4,593 SF
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Parkway Plaza
4215 University Drive, Valley Run, Durham, NC
Space Type
Retail
1 space

3,173 SF
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$7.50 - $8.00/SF/YR
1500 E Club Blvd
1500 E Club Blvd, Crown Point, Durham, NC
Space Type
Industrial
1 space

31,710 SF
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Central Professional Park
2609 North Duke Street, West Murray - Broad, Durham, NC
Space Type
Office
1 space

5,371 SF
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Price on request
2505 Meridian
2505 Meridian Parkway, Copper Creek, Durham, NC
Space Type
Office
3 spaces

2,005 - 4,604 SF
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$23.00/SF/YR
4321 Medical Park Dr
4321 Medical Park Dr, Summer Meadow, Durham, NC
Space Type
Office
3 spaces

4,257 - 10,056 SF
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Price on request
1101 Hamlin Road
1101 Hamlin Road, Falls Lake, Durham, NC
Space Type
Industrial
3 spaces

36,378 - 96,386 SF
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$550,000
3719 University Dr, Suite A
3719 University Drive, Valley Run, Durham, NC
Property Type
Office
Built in 1994

1,677 SF

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Durham, NC Commercial Real Estate Market Overview: Key Trends & Insights

Durham has 12.0 million square feet of commercial real estate inventory as of 2026. This inventory is distributed across nearly 300 properties.

This overview provides a snapshot of the Durham commercial sector, highlighting the most important aspects and trends to guide you through the local landscape, whether you are looking to lease or invest in local CRE assets.

Commercial Space for Rent in Durham, NC

Based on the latest estimates, Durham, NC offers almost 300 commercial listings for lease, totaling about 12.0 million square feet.

Current leasing options comprise 139 office listings, which represent approximately 58.16% out of the total leasing inventory. There are also 44 industrial and warehouse listings, making up 18.41% of the total. Additionally, 56 retail listings make up 23.43% of the local leasing market. These types are supplemented by 19 listings for lease belonging to other commercial types.

Property type No. of Listings Total Sq. Ft. Avg. Asking Rent

Office 139 13,034,738 $33.69

Retail 56 4,514,055 $27.31

Industrial 44 4,959,155 $12.21

Other 19 1,128,258 N/A

Commercial Real Estate for Sale in Durham, NC

As of 2026, Durham, NC has a total of 58 commercial real estate properties for sale.

This inventory includes 11 office assets, 8 industrial facilities and 6 retail properties available for purchase.

The largest share is held by Office, with 18.97% out of local properties for sale belonging to this asset type. Industrial has the next largest share at 13.79%, while Retail makes up 10.34% of commercial properties for sale in Durham.

Property type No. of Listings Total Sq. Ft.

Office 11 13,034,738

Retail 6 4,514,055

Industrial 8 4,959,155

Other 33 11,842,017

Leading Commercial Real Estate Submarkets by Property Type in Durham, NC

The leading commercial real estate submarkets for different property types in Durham are:

Office: Research Triangle Park with 160 office listings, totaling 2,529,624 square feet.
Industrial: Research Triangle Park with 10 industrial listings, totaling 918,141 square feet.
Retail: Downtown Durham with 17 retail listings, totaling 45,116 square feet.