Map of Property

For Lease

Snyder Commons

4600 Main Street, Buffalo, NY 14226

6,205

SF Available

Multi-tenant office building at Snyder Commons. Flexible sale or lease opportunity. Two suites currently available. Move-in ready office space with efficient floor plans and quality existing finishes. Convenient, accessible Main Street location. Close proximity to NYS I-90 and I-290 Thruways. Surrounded by established residential neighborhoods and businesses. Near restaurants, retail, and Daemen College. Ample on-site parking. Bus line access and signage opportunities. Ideal For: investors, owner-occupiers, medical and professional office users.   

Rental Details

  • Number of spaces 2
  • Total square feet available 6,205 SF
  • For Lease $22.00/SF/YR
  • Space Types Medical Office
  • Lease Type NNN
  • Date Updated Feb 16, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

For Lease 2 Spaces Available

Contacts

Lucian Issa

Cushman & Wakefield | Pyramid Brokerage

John Ticco III

Cushman & Wakefield | Pyramid Brokerage

Robert Stewart

Cushman & Wakefield | Pyramid Brokerage

Building Details

  • For Lease $22.00/SF/YR
  • Property Type Office
  • Property Size 10,120 SF
  • Lot Size 0.58 Acre
  • Year Built 1988
  • Date Updated Feb 16, 2026

Getting Around

  • Walk Score ®

    Very Walkable (73)

  • Bike Score ®

    Bikeable (53)
Powered by Walk Score ®

Location

  • City Buffalo, NY
  • Zip Code 14226
  • Market Buffalo

Points of Interest

Hertel & Voorhees

3.27 miles

Hertel & Vorrhees

3.29 miles

Hertel & Starin

3.39 miles

Hertel & Wellington

3.76 miles

Humboldt–Hospital

4.36 miles

Metro Rail Station

6.30 miles

Marina Vista Apartments

6.65 miles

Lafayette Square

7.10 miles

Buffalo–Exchange Street Station

7.52 miles

Valero

0.65 miles

Marathon

1.10 miles

ChargePoint

1.17 miles

Mobil

1.23 miles

Kwik-Fill

1.43 miles

Tesla Destination Charger

3.42 miles

Tesla Supercharger

3.95 miles

Main St. and Union St. Park and Ride Lot

1.25 miles

Michael-Farber Lot (f/s,st)

1.84 miles

Main-Bailey Lot (f/s,st)

1.86 miles

Goodyear Lot (f/s)

1.87 miles

Tower Lot (Clinic Patient Parking)

1.91 miles

VA Parking

1.92 miles

Sherman Lot (f/s,st)

1.92 miles

Squire Lot (Dental Patient Parking)

1.94 miles

Allen Lot (f/s,st)

1.95 miles

Hertz

1.34 miles

Budget

1.36 miles

Avis

1.36 miles

Enterprise

1.55 miles

Schmitt's Robo Carwash

2.20 miles

Better Vision Car Spa

2.82 miles

Classy Classy Car Wash

2.85 miles

Delta Sonic Car Wash

2.89 miles

Alamo

3.18 miles

Siena

0.14 miles

Adam's Rib

0.16 miles

Bruegger's Bagels

0.18 miles

Denny's

0.25 miles

Rin Thai Bistro

0.26 miles

Jazzboline Restaurant & Bar

0.57 miles

Concession Stand

0.61 miles

Kumiko Sushi & Thai

0.70 miles

Salt Cuisine

0.71 miles

Tops

1.00 miles

Pacillo's Fitness Gear

1.67 miles

Sheridan Market

1.91 miles

Bailey Express Market

2.05 miles

Fair Price Halal Meat, Grocery & Food

2.07 miles

Walmart Supercenter

2.08 miles

An Chau Asian Market

2.11 miles

Ni Hoowa Supermarket

2.14 miles

Super Bazaar

2.15 miles

Snyder Fire District

0.12 miles

Buffalo Infertility & IVF Associates

0.16 miles

Orthosports Physical Therapy

0.79 miles

WellNow Urgent Care

0.87 miles

Walgreens

0.91 miles

CVS Pharmacy

1.03 miles

WNY Immediate Care

1.06 miles

Cleveland Hill Fire Department No.6

1.22 miles

Walgreens Drive-Thru

1.31 miles

4600 Main Street Listing Summary

  • Office Space Available at 4600 Main Street

    Office space currently available at 4600 Main Street adds up to a total of 6,205 square feet across 2 listing(s). The largest individual space listed offers 3,177 square feet. Property use types available for lease at this property include: medical office.

  • Learn More about 4600 Main Street

    4600 Main Street is located in the Buffalo market and pertains to the 14226 zip code. The property incorporates a total of 6,205 square feet of space. Within the same building, there are 3,177 square feet of space. 4600 Main Street was built in 1988.

    Interested in researching more about this property? Access in-depth research on 4600 Main Street, including ownership details, transaction history, property characteristics, taxes, mortgage data, violations and more by creating a free account and viewing the full property report.

Contact Snyder Commons
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  2. 2Extra information
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